Bacteriophage-Host Cell Interactions: From Biology to the Control of Bacterial Infection
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: closed (30 October 2023) | Viewed by 2751
Special Issue Editor
Interests: bacteriophage; endolysin; holin; lysin; bacterial cell wall; bacterial receptor; receptor-binding protein; antibiotic resistance; phage therapy; phage-based bacterial detection
Special Issue Information
Dear Colleagues,
Bacteriophages (phages) were first described more than a century ago, and it was immediately discovered that their bactericidal activity could be used to treat bacterial infections (phage therapy). Research on understanding how phages infect and interact with bacterial hosts in different environments has provided answers to fundamental questions in biology and this research is linked to the very foundations of molecular biology. Phage research maintained its relevance over the years, being at the forefront of fundamental discoveries and major technological revolutions, with the CRISPR-Cas systems being one of the most recent and famous examples.
This Special Issue of Microorganisms intends to collate both reviews and original research articles that help to understand any aspect of phage–host cell interactions and ultimately how this knowledge can be utilized for certain applications. In the context of alternative approaches to respond to the escalating problem of antibiotic resistance, articles describing phage-based strategies (phages or their proteins) applied to the control of bacterial infection in different settings are particularly welcome. Some focal areas include, but are not limited to, the following:
- Understanding phage interaction with the host cell envelope and how phages cope with the bacterial cell barriers;
- Use of phages and their derived proteins in the design of strategies to detect and/or fight bacteria in different contexts;
- Bacterial response and defense mechanisms to phage infection and phage countermeasures.
Dr. Carlos São-José
Guest Editor
Manuscript Submission Information
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Keywords
- bacteriophages
- phage therapy
- bacterial infections
- bacteriophage–host interactions
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