Antimicrobial Stewardship: Strategies for Optimizing Antimicrobial Use and Combating Resistance

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 265

Special Issue Editor


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Interdisciplinary Center for Modern Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland
Interests: microorganisms (isolation, identification); antimicrobial activity/cytotoxicity (clasical methods, e.g., well diffusion method, fluorescence microscope as well as modern techniques such as flow cytometry); use of microorganisms for searching of innovative agents (e.g., Me/MeO nanoparticles, nanocomposites) and their application in medicine, veterinary, cosmetics and food industry
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Special Issue Information

Dear Colleagues,

Antimicrobial stewardship is a critical strategy for optimizing the use of antimicrobial agents and combating the global threat of antimicrobial resistance. As the overuse and misuse of antibiotics and other antimicrobial drugs have contributed to the rise of drug-resistant pathogens, healthcare providers and institutions are implementing comprehensive stewardship programs to ensure the appropriate, safe, and effective utilization of these vital medical resources. Optimizing antimicrobial therapy is a critical component of antimicrobial stewardship programs. By carefully selecting the appropriate antimicrobial agent, dosage, and duration of treatment, healthcare providers can help improve patient (human and animals) outcomes, minimize the development of antimicrobial resistance, and reduce the risk of adverse drug events.

In this Special Issue, we will discuss how maintaining the long-term success and effectiveness of an antimicrobial stewardship program (ASP) requires a commitment to continuous quality improvement and sustainability. This involves regularly evaluating the program's impact, identifying areas for optimization, and implementing data-driven changes to ensure the program continues to meet the evolving needs of the healthcare facility and patient population.

Key strategies for continuous quality improvement and sustainability include the following:

Implementing Stewardship Programs: This includes implementing guidelines, policies, and protocols to standardize antimicrobial prescribing practices, as well as education and training for healthcare providers on appropriate antimicrobial use. Ongoing monitoring and surveillance of antimicrobial utilization and resistance patterns are also crucial elements of a successful ASP.

Strategic Stewardship Interventions: These interventions aim to promote the optimal selection, dosing, duration, and route of antimicrobial administration. Effective implementation of these strategies can lead to improved patient outcomes, reduced antimicrobial resistance, and cost savings for healthcare systems.

Multidisciplinary Collaboration: Successful antimicrobial stewardship requires a collaborative, multidisciplinary approach involving a variety of specialists as well as scientific researchers and other healthcare professionals. By leveraging the expertise of this team, ASPs can effectively implement evidence-based interventions, provide tailored education, and foster a culture of responsible antimicrobial use within the healthcare organization.

Dr. Viorica Railean
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial stewardship
  • antimicrobial agent
  • antimicrobial therapy
  • dosing optimization
  • healthcare
  • antimicrobial surveillance and monitoring
  • human medicine
  • veterinary medicine
  • multidisciplinary
  • stewardship programs

Published Papers (1 paper)

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Research

12 pages, 281 KiB  
Article
Evaluation of the Impact of Antibiogram Availability and Utilization on Antibiotic Use among Healthcare Providers in Saudi Arabia: A Cross-Sectional Study
by Haytham A. Wali, Hassan Ali Alhajji, Ridha Alsaeed, Abdullah Aldughaim, Rakan Almutairi and Amira S. Radwan
Microorganisms 2024, 12(7), 1444; https://doi.org/10.3390/microorganisms12071444 - 16 Jul 2024
Viewed by 197
Abstract
Antibiotic resistance is a significant global health issue, exacerbated by the indiscriminate use of antibiotics without antibiograms. Implementing appropriate stewardship programs that monitor and control antibiotic use is essential to minimize resistance development and ensure optimal patient outcomes. This study aims to assess [...] Read more.
Antibiotic resistance is a significant global health issue, exacerbated by the indiscriminate use of antibiotics without antibiograms. Implementing appropriate stewardship programs that monitor and control antibiotic use is essential to minimize resistance development and ensure optimal patient outcomes. This study aims to assess the impact of antibiogram availability and utilization on antibiotic use among healthcare providers in Saudi Arabia, focusing on whether antibiogram data and utilization influence the appropriateness of antibiotic prescribing practices. A cross-sectional study design was employed, utilizing a self-administered online survey distributed to physicians, pharmacists, and other healthcare providers across various healthcare settings in Saudi Arabia. Data were collected over a 90-day period, from December 1, 2023, to February 29, 2024. Descriptive statistics were used to summarize participants’ characteristics, and data were analyzed based on geographical region, participants’ positions, and other predetermined differences. Out of 23,860 contacted individuals, 333 responded, and 283 were included in the analysis. The majority (62.2%) reported the availability of antibiograms at their facilities, with 84.1% utilizing them in clinical practice. The frequency of consulting antibiograms varied, with only 21.6% doing so daily. Key barriers to antibiogram availability included lack of expertise, technological infrastructure, and funding. Most participants (68.8%) observed changes in antibiotic prescription practices post-antibiogram introduction, and 86.9% believed antibiograms could shorten patients’ length of stay and improve outcomes. However, only 40.9% had received training on antibiogram use. While healthcare providers in Saudi Arabia have a relatively high level of antibiogram availability and utilization, several barriers hinder their consistent use. Enhancing accessibility, promoting frequent use, and providing targeted training could strengthen the impact of antibiograms on antibiotic prescribing practices and antimicrobial stewardship efforts. Full article
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