Latest Research on Clostridioides difficile
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 1357
Special Issue Editor
Interests: microbiology; epidemiology; pathology; treatmen; diagnostics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The pathology of diseases caused by Clostridioides difficile (CD) has been augmented over time by changing population dynamics, healthcare, and agriculture practices and the varied genetics of the organism. Among these changes are the introduction of broad-spectrum antibiotics; the emergence of an outbreak-related strain, NAP1/027; and the consequences of the COVID-19 pandemic. During the pandemic, improved infection control methods decreased the incidence of hospital-acquired CD infection (CDI) but research on the biology, epidemiology, and treatment of CDI stagnated.
Recently, there has been renewed interest in previously developed methods of controlling this infection, including therapy with fecal microbiota transplants; using a mix of beneficial bacteria, therapeutic proteins, antibiotics; and the development of toxoid-based vaccines. The efficiency of these methods and newly developed approaches is also continually affected by the changing characteristics of CDI; its features have changed due to the replacement of hospital-acquired infections with community-acquired cases and more efficient infection control in hospitals.
This Special Issue aims to present new information on various aspects of this pathogen: its biology, the pathology of the disease, existing methods of detection, epidemiology, treatment options and approaches, and the healthcare costs of the disease.
As the Guest Editor of this Special Issue, I invite you to submit research articles, reviews, and short communications related to Clostridioides difficile.
Prof. Dr. George Broukhanski
Guest Editor
Manuscript Submission Information
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Keywords
- Clostridioides difficile
- biology
- epidemiology
- pathogenicity
- detection
- treatment
- infection control
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