Strengthening Mucosal Immunity and the Intestinal Microbiome with Probiotics and Prebiotics
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: closed (20 November 2019) | Viewed by 37034
Special Issue Editor
Interests: clinical epidemiology; the human microbiome; probiotics and prebiotics and mood disorders; cellular redox potential and pro-oxidant signaling systems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The commensal microbial cohort functions to develop and establish the host’s mucosal and cell-mediated immune systems in order to promote immunological and metabolic tolerance. Probiotics and prebiotics have been advanced to have immunomodulating properties by positively influencing the intestinal microbial cohort while simultaneously diminishing the influence and activity of pathogenic intestinal bacteria such as Klebsiella pneumoniae and Clostridia perfringens. Specifically, probiotics and prebiotics are reported to have positive immuno-equilibrium restorative effects. An increasingly supported posit is that bacteria such as those from the probiotic genera Bifidobacteria and Lactobacilli can participate in immune regulation, and do so by inducing regulatory T cells. Reports of beneficial immune-modulatory effects by probiotic bacteria are elicited across several molecules, which include microbial cell walls, peptidoglycan, and exopolysaccharides, through interactions with specific host cell receptors. Whereas relative to prebiotics, these are compounds portrayed to encourage the intestinal microbiome’s production of short-chain fatty acids such as butyrate, which have a central role in intestinal immunogenicity. Moreover, bacteriophages may display an additional effective local protective control mechanism for the intestinal barrier against commensal pathogenic bacteria.
Prof. Luis Vitetta
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Mucosal Immunity
- Cell Mediated Immunity
- Immunological Tolerance
- Probiotics
- Prebiotics
- Lactobacilli
- Bifidobacteria
- Intestinal Microbiome
- Bacteriophages
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.