Immunopathology of Toxoplasma gondii Infection
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Parasitology".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 4374
Special Issue Editors
Interests: toxoplasmosis; immunopathology; drug discovery; vaccines; maternal-fetal
Special Issues, Collections and Topics in MDPI journals
Interests: toxoplasmosis; neosporosis; immunopathology; vaccines; pregnancy
Special Issue Information
Dear Colleagues,
Toxoplasma gondii is an apicomplexan parasite found throughout the world and the etiologic agent of toxoplasmosis. This parasite is of major human clinical importance since it causes serious complications from the fetus to adulthood, namely when primary infection or reactivation occurs in pregnant women and immunocompromised individuals. Its pathology varies according to several factors, including the genotype and immunological status of the host, parasite genotype, and virulence factors. A lack of knowledge exists concerning the unique host cell-mediated mechanisms and parasite molecular targets involved in parasite persistence and the induction of pathology. There still no human vaccines available and the current chemotherapy lacks efficacy against tissue cysts, with safety concerns due to the induction of adverse side effects associated with poor compliance within patients.
This Special Issue of Microorganisms aims to present a collection of articles that highlight research in the field of toxoplasmosis. Manuscripts covering all aspects of research relating to toxoplasmosis are welcome, including work from applied areas, such as novel drug targets and respective promising compounds, vaccines avoiding parasite invasion, proliferation and persistence and, thus, pathogenesis.
Dr. Margarida Borges
Dr. Valeria Sander
Guest Editors
Manuscript Submission Information
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Keywords
- Drug discovery
- Immunopathology
- Toxoplasmosis
- Vaccines
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