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Chemical Analysis of Functional Foods

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 2032

Special Issue Editors


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Guest Editor
Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy
Interests: NMR; food chemistry; functional foods; food authentication; metabolomics; analytical chemistry; chromatography; chemometrics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy
Interests: NMR; food chemistry; functional foods; food authentication; metabolomics; analytical chemistry; chromatography; chemometrics; drug delivery systems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nowadays, more and more consumers are aware of the benefits associated with a balanced and healthy diet. As a consequence, consumer interest in functional foods that are high in bioactive/nutraceutical compounds is growing. Functional foods are defined as foods or food ingredients that provide health benefits besides basic nutrition. The role of scientists is essential for discovering, designing, and characterizing new functional foods. Experts in the field of chemical analysis play a central role in this context as chemical analysis ensures the safety and quality of functional foods, protecting consumers from any risk. Moreover, chemical analysis allows the complete characterization of foods in terms of the identification and quantification of bioactive compounds.

This Special Issue, entitled “Chemical Analysis of Functional Foods”, will showcase high-quality contributions both in the form of original and innovative research and review articles. The main objective is to cover studies focused on the chemical characterization of functional foods and the development of analytical methods for the quality control of functional foods. The employment of multivariate statistical analyses for chemical data interpretation is encouraged, as are multidisciplinary approaches where food chemistry, biology, and nutrition are interconnected.

Dr. Davide Bertelli
Dr. Eleonora Truzzi
Guest Editors

Manuscript Submission Information

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Keywords

  • functional foods
  • nutraceuticals
  • metabolomics
  • advanced analytical techniques
  • chemometrics

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Published Papers (3 papers)

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Research

19 pages, 2713 KiB  
Article
Chemical Characterization and Beneficial Effects of Walnut Oil on a Drosophila melanogaster Model of Parkinson’s Disease
by Rossella Avallone, Cecilia Rustichelli, Monica Filaferro and Giovanni Vitale
Molecules 2024, 29(17), 4190; https://doi.org/10.3390/molecules29174190 - 4 Sep 2024
Viewed by 319
Abstract
A nutritional approach could be a promising strategy to prevent or decrease the progression of neurodegenerative disorders such as Parkinson’s disease (PD). The neuroprotective role of walnut oil (WO) was investigated in Drosophila melanogaster treated with rotenone (Rot), as a PD model, WO, [...] Read more.
A nutritional approach could be a promising strategy to prevent or decrease the progression of neurodegenerative disorders such as Parkinson’s disease (PD). The neuroprotective role of walnut oil (WO) was investigated in Drosophila melanogaster treated with rotenone (Rot), as a PD model, WO, or their combination, and compared to controls. WO reduced mortality and improved locomotor activity impairment after 3 and 7 days, induced by Rot. LC-MS analyses of fatty acid levels in Drosophila heads showed a significant increase in linolenic (ALA) and linoleic acid (LA) both in flies fed with the WO-enriched diet and in those treated with the association of WO with Rot. Flies supplemented with the WO diet showed an increase in brain dopamine (DA) level, while Rot treatment significantly depleted dopamine content; conversely, the association of Rot with WO did not modify DA content compared to controls. The greater intake of ALA and LA in the enriched diet enhanced their levels in Drosophila brain, suggesting a neuroprotective role of polyunsaturated fatty acids against Rot-induced neurotoxicity. The involvement of the dopaminergic system in the improvement of behavioral and biochemical parameters in Drosophila fed with WO is also suggested. Full article
(This article belongs to the Special Issue Chemical Analysis of Functional Foods)
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18 pages, 738 KiB  
Article
Phytochemical Characterization of Two New Olive Oil Genotypes Growing in Southern Tunisia
by Mbarka Ben Mohamed, Sihem Ben Ali, Gabriele Rocchetti, Samir Tlahig, Leila Bennani and Ferdaous Guasmi
Molecules 2024, 29(17), 3997; https://doi.org/10.3390/molecules29173997 - 23 Aug 2024
Viewed by 422
Abstract
This research can be considered as the first complete survey for the valorization of new olive genotypes cultivated in the South-East of Tunisia as well as their oils. The study aimed to characterize the phytochemical composition of virgin olive oil produced from two [...] Read more.
This research can be considered as the first complete survey for the valorization of new olive genotypes cultivated in the South-East of Tunisia as well as their oils. The study aimed to characterize the phytochemical composition of virgin olive oil produced from two olive cultivars, namely Nourgou and Gousalani. The pomological characterization of fruits, the quality criteria and the phytochemical profile were quantified. Additionally, antioxidant activity was evaluated using Ferric reducing antioxidant power (FRAP) and Oxygen radical absorbance capacity (ORAC) tests to also obtain a bioactive characterization of these monovarietal olive oils. The obtained results revealed that the analyzed olive oils samples can be classified into Extra Virgin category (EVOO) according to the regulated physicochemical characteristics. Our findings showed a significant variability in the chemical parameters of the analyzed EVOO likely associated with the genetic potential, mainly for chlorophylls contents (1.37–1.64 mg/kg), in carotenoids pigments (3.97–10.86 mg/kg), in α-tocopherol (175.59–186.87 mg/kg), in sterols (1036.4–1931.4 mg/kg) in oleic acid (65.33–68.73%), in palmitic acid (C16:0) (13.32–17.48%), in linoleic acid (C18:2) (11.06–13.47%). Additionally, the HPLC-MS/MS analysis showed that the two EVOOs analyzed contained appreciable amounts of total polyphenols, ranging from 348.03 up to 516.16 mg/kg, in Nourgou and Gousalani oils, respectively. Regarding the individual phenolic compounds, the EVOO samples were mainly characterized by phenolic alcohols, phenolic acids, secoiridoids, verbascoside, flavonoids and phenolic aldehydes. The prevalent simple phenolics detected were secoiridoids with the dominance of the oleuropein aglycone in Gousalani oil. In addition, findings from in vitro antioxidant assays (FRAP and ORAC) revealed that the two studied oils possessed a powerful antiradical activity and a good reducing power capacity. In conclusion, these new EVOOs exhibited a superior quality compared to other Tunisian varieties, considering their antiradical activity and reducing power capacity. Full article
(This article belongs to the Special Issue Chemical Analysis of Functional Foods)
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14 pages, 5483 KiB  
Article
Widely Targeted Metabolomics Analysis Reveals Metabolites Important for Antioxidant Properties and Quality Traits in Different Fruit Parts of Aurantii Fructus Immatures
by Shuo Zhang, Ze Liu, Xinyu Xu, Ruihua Zhao, Shujiang Zhang and Rong Luo
Molecules 2024, 29(8), 1733; https://doi.org/10.3390/molecules29081733 - 11 Apr 2024
Viewed by 803
Abstract
In traditional Chinese medicine, Aurantii Fructus Immatures (AFIs) have been utilized for more than 2000 years. The proportions of different fruit parts are crucial for evaluating AFI quality in China. However, the basis for this statement’s substance is unclear. Differences in quality are [...] Read more.
In traditional Chinese medicine, Aurantii Fructus Immatures (AFIs) have been utilized for more than 2000 years. The proportions of different fruit parts are crucial for evaluating AFI quality in China. However, the basis for this statement’s substance is unclear. Differences in quality are intimately correlated with a plant’s metabolite composition. On the basis of a widely targeted metabolome, this study intended to investigate the metabolite composition and evaluate the antioxidant capacity of the peel and pulp of an AFI. Metabolites were identified and quantified by UHPLC-QqQ-MS. To assess their antioxidant ability, DPPH and ABTS assays were carried out. There were 1327 chemical compounds identified by UHPLC-QqQ-MS. After screening the differential metabolites using a multivariate statistical analysis, it was found that there were 695 significant differences in the metabolites between the peel and the pulp. Among them, it was discovered that the content of active ingredients in the peel group was higher than that in the pulp group. Furthermore, the aqueous extracts from the peel showed stronger antioxidant capacities than those from the pulp. The metabolites and antioxidant capacities were significantly different between the peel and the pulp. This study of different fruit parts might provide a guide for AFI quality assessments. Full article
(This article belongs to the Special Issue Chemical Analysis of Functional Foods)
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