Biobased Materials for Tissue Engineering
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 4574
Special Issue Editor
Interests: tissue engineering; scaffolds; chitosan; biopolymers; nanotechnology; biomedical applications; bone tissue engineering; wound healing; antimicrobial properties
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Globally, there is a growing demand for more environmentally friendly materials due to the concern generated by the excessive use of plastic and other recalcitrant materials derived from fossil fuels, whose environmental impact has become evident and seems irreversible. Biopolymers are a part of these environmentally friendly materials, especially those that come from renewable natural sources, and their production is increasing year after year thanks to their attractive properties for the food, cosmetic, and pharmaceutical industries. On the other hand, tissue engineering and regenerative medicine remain a challenge for humanity. The development of new, more controlled, and adaptable preparation techniques for a design much closer to natural tissues, such as electrospinning and 3D printing, has allowed publications to continue to increase in this field. Traditionally, tissue engineering has been based on the use of tissue fragments from the patient himself (autografts) or from a donor (allografts) or also from external origin (xenografts) such as animals, which on many occasions has generated complications due to rejection or infection in the patient, even leading to death. Many scaffolds are developed from biocompatible synthetic polymers such as polylactic acid, polyvinyl alcohol, and polycaprolactone due to their easy availability, synthetic adaptability, and excellent mechanical and strength properties. However, they often present limitations that do not allow their exclusive use for the design of scaffolds that support cell adhesion and proliferation for the renewal of tissue architecture. Therefore, scaffolds based on natural polymers such as chitosan, collagen, cellulose, polyhydroxyalkanoates, starch, and alginate, among others, have also been used.
In general, an appropriate strategy to mitigate the drawbacks in the design and development of biopolymer-based scaffolds is to develop physical mixtures between polymers, chemically functionalize the components, or incorporate nanomaterials that help to reinforce the mechanical properties of the material and other additional properties that allow a better performance of the material such as antimicrobial activity, immunomodulation, stimulation of angiogenesis, etc.
In this Special Issue, we have focused on using biobased materials for tissue engineering and several strategies for their fabrication and applications. This Special Issue represents an excellent opportunity for researchers to present their latest work addressing fundamental aspects and applied research within this field. This Special Issue will also highlight new challenges in developing more efficiently producing or designing films for specific applications.
Dr. Carlos David Grande Tovar
Guest Editor
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Keywords
- biobased materials
- biopolymers
- scaffold development
- tissue engineering
- regenerative therapy
- cell culture
- stem cell therapy
- drug delivery
- hydrogels
- wound dressing
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