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Fluorescent Probes in Biomedical Detection and Imaging

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 599

Special Issue Editor


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Guest Editor
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
Interests: fluorescent probes; nano drug delivery systems; disease theranostic; targeted drug development; clinical translation

Special Issue Information

Dear Colleagues,

Fluorescent probes have emerged as valuable tools for visualizing and studying biological processes at the molecular level, enabling researchers to gain deeper insights into various biological phenomena. This Special Issue invites contributions from researchers, scientists, and experts, working interdisciplinarily and in the areas of chemistry, biology, medicine, and materials science. The goal is to showcase cutting-edge research on the development, design, synthesis, and characterization of fluorescent probes, as well as their uses in biological detection and imaging.

This Special Issue aims to foster collaboration, the exchange of ideas, and the dissemination of novel findings in the field of fluorescent probes for biomedical detection and imaging. Both original research articles and review articles that provide a comprehensive and critical analysis of this exciting area of research are encouraged. Researchers are invited to contribute their high-quality papers to this Special Issue, to enhance our understanding and utilization of fluorescent probes in cutting-edge biomedical research, and further their potential applications.

Dr. Haihao Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fluorescent probes
  • fluorescent sensors
  • chemosensors
  • organic fluorescent molecules
  • detecting
  • bioimaging
  • theranostics
  • biomedicine
  • in vitro imaging
  • in vivo imaging

Published Papers (1 paper)

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Research

13 pages, 4521 KiB  
Communication
Synthesis and Characterization of Sulfonamide-Containing Naphthalimides as Fluorescent Probes
by Zhi-Wei Liu, Fan Liu, Chun-Tao Shao, Guo-Ping Yan and Jiang-Yu Wu
Molecules 2024, 29(12), 2774; https://doi.org/10.3390/molecules29122774 - 11 Jun 2024
Viewed by 420
Abstract
A tumor-targeting fluorescent probe has attracted increasing interest in fluorescent imaging for the noninvasive detection of cancers in recent years. Sulfonamide-containing naphthalimide derivatives (SN-2NI, SD-NI) were synthesized by the incorporation of N-butyl-4-ethyldiamino-1,8-naphthalene imide (NI) into sulfonamide (SN) and sulfadiazine (SD) as the tumor-targeting [...] Read more.
A tumor-targeting fluorescent probe has attracted increasing interest in fluorescent imaging for the noninvasive detection of cancers in recent years. Sulfonamide-containing naphthalimide derivatives (SN-2NI, SD-NI) were synthesized by the incorporation of N-butyl-4-ethyldiamino-1,8-naphthalene imide (NI) into sulfonamide (SN) and sulfadiazine (SD) as the tumor-targeting groups, respectively. These derivatives were further characterized by mass spectrometry (MS), nuclear magnetic resonance spectroscopy (1H NMR), Fourier transform infrared spectroscopy (FT-IR), ultraviolet–visible spectroscopy (UV), and a fluorescence assay. In vitro properties, including cell cytotoxicity and the cell uptake of tumor cells, were also evaluated. Sulfonamide-containing naphthalimide derivatives possessed low cell cytotoxicity to B16F10 melanoma cells. Moreover, SN-2NI and SD-NI can be taken up highly by B16F10 cells and then achieve good green fluorescent images in B16F10 cells. Therefore, sulfonamide-containing naphthalimide derivatives can be considered to be the potential probes used to target fluorescent imaging in tumors. Full article
(This article belongs to the Special Issue Fluorescent Probes in Biomedical Detection and Imaging)
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