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Applied Analytical Chemistry: Second Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 1036

Special Issue Editor


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Guest Editor
Dept Analyt Chem, Reg Ctr Adv Technol & Mat, Fac Sci, Palacky University, 17 Listopadu 12, 77146 Olomouc, Czech Republic
Interests: analytical chemistry; liquid chromatography; hyphenation of separation techniques (LC, CE) with mass spectrometry; natural compounds analysis; study of metabolism; analysis of archaeological samples; chiral separation; desorption/ionization mass spectrometry; ion mobility mass spectrometry; study of equilibrium reactions using retention and migration data
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Special Issue Information

Dear Colleagues,

Analytical Chemistry as a scientific field is a good example of the connection of fundamental research in chemical, physical, and biological branches to demands of practice. The mutual stimulation of fundamental and applied research makes analytical chemistry a dynamically developing area. The current high level of mechanical engineering and microelectronics is accelerating advancements in instrumental analytical techniques. Approaches to analytical data processing are being improved under the dictation of their increasing volume and with the possibilities of dramatically developing informatics. The optimization and validation of analytical procedures are becoming quicker and automated. However, sophisticated instrumentation, although supported by artificial intelligence, is not self-saving. Experience and thorough knowledge of possibilities and risks throughout the whole analytical procedure from the design of the experiment to the sampling, sample treatment, and analysis and data processing remain essential for successful research to be achieved. The integration of the entire analytical process and its transfer into practice is the subject of applied analytical chemistry.

This Special Issue aims to cover recent progress and trends in applied analytical chemistry. Papers focused on novel sampling and sample treatment procedures and the utilization of up-to-date techniques and methods in analytical practice are welcome to be submitted. Moreover, progressive approaches in the design of experiments and data processing proven in real situations fit within the scope of this Special Issue. Emphasis should be placed on the integrity of the whole analytical process. This Special Issue is open to all types of analytical techniques and the application of their (synergistic) combinations, with particular focus on the following, but not limited to, areas:

  • Food production;
  • Forensic practice and archaeology;
  • Environmental monitoring;
  • Clinical practice;
  • Quality control in industry;
  • Analysis of plant material.

Dr. Petr Bednar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food production
  • forensic practice and archaeology
  • environmental monitoring
  • clinical practice
  • quality control in industry
  • analysis of plant material

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Related Special Issue

Published Papers (2 papers)

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Research

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15 pages, 2426 KiB  
Article
Regulatory Effects of Chlormequat Chloride on the Yield and Chemical Composition of Angelica sinensis Radix
by Honghan Qin, Juan Xu, Xiaojun Ma, Rongchang Wei and Zuliang Luo
Molecules 2024, 29(19), 4725; https://doi.org/10.3390/molecules29194725 - 6 Oct 2024
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Abstract
Chlormequat chloride (CCC), as a commonly used plant growth regulator in the production of rhizomatous medicinal herbs, can effectively control the bolting phenomenon in Angelica sinensis, significantly increasing the yield of underground rhizomes (medicinal part). However, its specific effects on the intrinsic [...] Read more.
Chlormequat chloride (CCC), as a commonly used plant growth regulator in the production of rhizomatous medicinal herbs, can effectively control the bolting phenomenon in Angelica sinensis, significantly increasing the yield of underground rhizomes (medicinal part). However, its specific effects on the intrinsic quality of Angelica sinensis, especially medicinal components, require further investigation. The objective of this study is to conduct a thorough examination of CCC residue and its influence on the yield and medicinal components of Angelica sinensis. By spraying different concentrations of CCC on Angelica sinensis, we systematically monitored the final yield of Angelica sinensis Radix (ASR) in each treatment group and the residual concentration of CCC in ASR. Using UPLC-QTOF-MS technology, we conducted an in-depth analysis of the metabolic profile of ASR. Subsequently, UFLC-MS/MS was employed to accurately quantify the changes in the content of nine key active components in ASR. The results of this study indicate that the application of CCC significantly improves the yield of ASR, with the best effect observed at 0.1 g/L, resulting in a yield increase of 24.8%. Meanwhile, the residual amount of CCC in ASR is positively correlated with the application concentration, with the residual levels as high as 7.12 mg/kg in the high-concentration treatment group. Metabolomic analysis preliminarily identified 21 chemical components in ASR, including four organic acids and 13 phthalides. It is worth noting that the quantitative analysis results indicate significant changes in active components such as butylphthalide, Z-ligustilide, and ferulic acid after the application of CCC. Specifically, high-concentration CCC significantly increased the content of butylphthalide and levistolide A, while low-concentration CCC significantly promoted the accumulation of coniferyl ferulate and senkyunolide A, accompanied by a significant decrease in Z-ligustilide and ferulic acidy. In conclusion, while CCC use can increase yield, the associated increase in residues and imbalanced composition ratios may threaten the quality and safety of ASR. Therefore, it is crucial to control the amount of CCC used rationally to balance yield enhancement and quality assurance. Full article
(This article belongs to the Special Issue Applied Analytical Chemistry: Second Edition)
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Review

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31 pages, 7846 KiB  
Review
Perspectives in Aptasensor-Based Portable Detection for Biotoxins
by Congying Li, Ziyuan Zhu, Jiahong Yao, Zhe Chen and Yishun Huang
Molecules 2024, 29(20), 4891; https://doi.org/10.3390/molecules29204891 (registering DOI) - 15 Oct 2024
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Abstract
Biotoxins are pervasive in food and the environment, posing significant risk to human health. The most effective strategy to mitigate the risk arising from biotoxin exposure is through their specific and sensitive detection. Aptasensors have emerged as pivotal tools, leveraging aptamers as biorecognition [...] Read more.
Biotoxins are pervasive in food and the environment, posing significant risk to human health. The most effective strategy to mitigate the risk arising from biotoxin exposure is through their specific and sensitive detection. Aptasensors have emerged as pivotal tools, leveraging aptamers as biorecognition elements to transduce the specificity of aptamer-target interactions into quantifiable signals for analytical applications, thereby facilitating the meticulous detection of biotoxins. When integrated with readily portable devices such as lateral flow assays (LFAs), personal glucose meters (PGMs), smartphones, and various meters measuring parameters like pH and pressure, aptasensors have significantly advanced the field of biotoxin monitoring. These commercially available devices enable precise, in situ, and real-time analysis, offering great potential for portable biotoxin detection in food and environmental matrices. This review highlights the recent progress in biotoxin monitoring using portable aptasensors, discussing both their potential applications and the challenges encountered. By addressing these impediments, we anticipate that a portable aptasensor-based detection system will open new avenues in biotoxin monitoring in the future. Full article
(This article belongs to the Special Issue Applied Analytical Chemistry: Second Edition)
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