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Compounds to Prevent and Control Foodborne and Waterborne Viruses

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".

Deadline for manuscript submissions: closed (1 June 2021) | Viewed by 3115

Special Issue Editor


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Guest Editor
Department of Microbiology and Ecology, University of Valencia, Valencia, Spain
Interests: food microbiology; water quality; food safety; enteric viruses; food processing; natural compounds

Special Issue Information

Dear Colleagues,

Contamination of food and water by human pathogenic viruses is a global public health concern. Despite vaccination and prevention campaigns controlled the impact of diseases caused by some viruses such as influenza, poliomyelitis, and measles, a significant number of viral food- and waterborne outbreaks still occur, with human norovirus recognized as the most common causative agent worldwide. Known (e.g., hepatitis A virus, rotaviruses, astroviruses), emerging (e.g., Aichi virus, Sapovirus), and re-emerging (e.g., hepatitis E virus) viruses represent underestimated risks in the food chain and water supply system.

The risk of cross-contamination can occur at any point in the chain: primary production, harvest manipulation, post-harvest processing, food service, handling surfaces, and sewage-polluted irrigation water or biosolids. Therefore, natural and chemical compounds exerting antiviral activity represent keystones in prevention and control strategies for foodborne and waterborne viruses.

The current Special Issue will publish original research and review papers on antiviral compounds of natural and synthetic origin and their application in food, water disinfection practices, and food–contact surface decontamination.

Dr. Walter Randazzo
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Natural compounds
  • Antivirals
  • Foodborne virus
  • Waterborne virus
  • Enteric virus
  • Food safety
  • Water disinfection
  • Surface decontamination
  • Prevention and control

Published Papers (1 paper)

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Research

15 pages, 1421 KiB  
Article
The Effect of GD1a Ganglioside-Expressing Bacterial Strains on Murine Norovirus Infectivity
by Yifan Zhu, Hiroki Kawai, Satoshi Hashiba, Mohan Amarasiri, Masaaki Kitajima, Satoshi Okabe and Daisuke Sano
Molecules 2020, 25(18), 4084; https://doi.org/10.3390/molecules25184084 - 7 Sep 2020
Cited by 3 | Viewed by 2732
Abstract
In this study, we investigated the impact of GD1a-expressing bacterial strains on the infectivity of murine norovirus (MNV). Eligible bacterial strains were screened from a sewage sample using flow cytometry, and their genetic sequences of 16S rRNA were determined. The enzyme-linked immunosorbent assay [...] Read more.
In this study, we investigated the impact of GD1a-expressing bacterial strains on the infectivity of murine norovirus (MNV). Eligible bacterial strains were screened from a sewage sample using flow cytometry, and their genetic sequences of 16S rRNA were determined. The enzyme-linked immunosorbent assay (ELISA) was employed to analyze the binding between bacteria and MNV particles, and the plaque assay was used to assess the effects of GD1a-positive and negative strains on MNV infectivity. The result from ELISA shows that MNV particles are able to bind to both GD1a-positive and negative bacterial strains, but the binding to the GD1a-positive strain is more significant. The infectivity assay result further shows that the MNV infectious titer declined with an increasing concentration of GD1a-positive bacteria. The addition of anti-GD1a antibody in the infectivity assay led to the recovery of the MNV infectious titer, further confirming that the binding between MNV particles and bacterial GD1a ganglioside compromises MNV infectivity. Our findings highlight the role indigenous bacteria may play in the lifecycle of waterborne enteric viruses as well as the potential of exploiting them for virus transmission intervention and water safety improvement. Full article
(This article belongs to the Special Issue Compounds to Prevent and Control Foodborne and Waterborne Viruses)
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