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Bioactive Compounds from Grape and Wine

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 3394

Special Issue Editor


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Guest Editor
Department of Agricultural Sciences, Grape and Wine Science Division, University of Naples “Federico II”, Viale Italia, 83100 Avellino, Italy
Interests: grape and wine polyphenols; wine oxidation; wine sensory active compounds; wine health active compounds; wine technology

Special Issue Information

Dear Colleagues,

Numerous are the aspects to consider when dealing with grape and wine compounds that are capable of modulating some human metabolic processes, resulting in beneficial effects. These compounds are transferred from grape to wine during winemaking and include a heterogeneous class of grape phytochemicals and metabolites derived from microbial transformations, having different chemical structures (they comprise mainly phenolic compounds, but also melatonin, terpenoids, etc.). The final health effect is, therefore, the result of a combination of different factors: the distribution of bioactive compounds in the grape cluster; their concentration in different wine types; their daily intake; their bioavailability and in vivo activity and stability. In addition, numerous agronomical, microbial, and technological practices can affect their concentration in grape and wine.

This Special Issue aims to attract contributions on all aspects of the chemistry and potential health activity of these grape and wine compounds, including the factors having an effect on their concentration in grape and wine and on their bioavailability.

Prof. Dr. Angelita Gambuti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • grape
  • wine
  • bioactive compounds
  • antioxidant activity
  • anti-inflammation activity
  • antimicrobial effect
  • anticancer activity

Published Papers (1 paper)

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Research

14 pages, 2292 KiB  
Article
Evolution of Flavanol Glycosides during Red Grape Fermentation
by Marie Zerbib, Guillaume Cazals, Marie-Agnès Ducasse, Christine Enjalbal and Cédric Saucier
Molecules 2018, 23(12), 3300; https://doi.org/10.3390/molecules23123300 - 12 Dec 2018
Cited by 1 | Viewed by 2978
Abstract
Monomeric and dimeric flavanol glycosides were quantified by UHPLC-MRM in Syrah (SYR) and Grenache (GRE) grapes and in their corresponding wines for the first time. Quantities were extremely variable depending on grape tissue (seeds or skins) and during fermentation. Overall, 22 monomeric and [...] Read more.
Monomeric and dimeric flavanol glycosides were quantified by UHPLC-MRM in Syrah (SYR) and Grenache (GRE) grapes and in their corresponding wines for the first time. Quantities were extremely variable depending on grape tissue (seeds or skins) and during fermentation. Overall, 22 monomeric and dimeric mono- and diglycosides were determined with concentrations ranging from 0.7 nanograms to 0.700 micrograms per gram of grape tissue, and 0 to 60 micrograms per liter for wines. The evolution of the glycosides’ composition during winemaking suggests that almost all these compounds originate in the grapes themselves and display different extraction kinetics during winemaking. One isomer of the monomeric (epi) flavanol monoglycosides seemed to be biosynthesized by yeasts during wine fermentation. The sharp decrease in concentration of some isomers at the late stages of fermentation or after pressing suggests that some grape glycosidase activities convert these compounds into non-glycosylated flavanols. Full article
(This article belongs to the Special Issue Bioactive Compounds from Grape and Wine)
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