Unlocking the Formulation Potential of Cyclodextrins and Their Derivatives—2nd Edition
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2811
Special Issue Editors
Interests: drug–protein binding; drug-cyclodextrins interaction, characterization and effect on drug solubility/dissolution/absorption; development and in vitro–in vivo evaluation of novel dosage forms with optimized absorption (GI/nasal/pulmonary); PK/PD studies and dosage individualization
Special Issues, Collections and Topics in MDPI journals
Interests: drug delivery systems; liposomes; polymers; nanotechnology; fractals
Special Issues, Collections and Topics in MDPI journals
Interests: development and in vitro–in vivo evaluation of novel nasal dosage forms with optimized absorption; characterization and effect on drug solubility/dissolution/absorption; pharmacokinetic studies
Special Issue Information
Dear Colleagues,
Cyclodextrins are water-soluble, biocompatible macrocyclic oligosaccharides made of α-d-glucopyranose units joined by α(1–4) linkages. These versatile molecules were discovered over a century ago. From then to now, cyclodextrins and their derivatives have served as drug delivery systems with several applications due to their added value in drug delivery precision and targeting.
This Special Issue constitutes the continuation of “Cyclodextrins and Their Derivatives: A Basis for New Drug Formulations—Volume I” and delves into the applications of cyclodextrins and their derivatives for the design and development of innovative drug formulations. This volume will focus on the different stages of cyclodextrin-based formulation development, spanning from initial conceptualization to their clinical applications. Special attention will be given to the drug–cyclodextrin interactions during pre-formulation studies as well as in the formulation process. Additionally, different routes of administration will be elucidated, emphasizing the importance of incorporating cyclodextrins in the formulation. Manuscripts featuring in vivo assessments of cyclodextrin-based formulations are strongly encouraged. This Special Issue places paramount significance on PK/PD studies of cyclodextrins and their derivatives. Both original manuscripts and reviews are welcome!
Prof. Dr. Georgia N. Valsami
Dr. Natassa Pippa
Guest Editors
Dr. Paraskevi Papakyriakopoulou
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- cyclodextrins
- cyclodextrin-drug interactions
- formulations
- drug loading
- release kinetics
- routes of administration
- in vitro-in vivo evaluation
- PK/PD studies
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