Opioids and Their Receptors
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (28 February 2024) | Viewed by 370
Special Issue Editor
Interests: pain pharmacology; chronic pain; inflammatory pain; chemotherapy induced neuropathic pain; trauma-induced neuropathic pain, glial cells; hyperalgesia; allodynia; in vivo approach; in vitro approach; therapeutic agents; pharmacological mechanism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Opioids, such as morphine, are the oldest analgesic drugs that we know of and are widely used as therapeutic agents against moderate to severe acute and chronic pain. However, these analgesics are characterized by several limitations, such as the development of analgesic tolerance, addiction, and others adverse effects that often result in patients non-compliance. All clinically used opioids are μ-opioid receptor agonists, and the major adverse effects are directly or potentially connected to this receptor. The aim of this Special Issue is to highlight recent advances in the basic pharmacology of opioids, with particular attention paid to the mitigation of their side effects and to the development of new safer medications in order to manage pain as well as addiction and overdose prevention.
This Special Issue welcomes original articles, communications, and review articles on recent advances and emerging concepts in opioid drug discovery and, more generally, opioid research.
Dr. Laura Micheli
Guest Editor
Manuscript Submission Information
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Keywords
- opioid pharmacology
- opioid receptors
- opioid side effects
- opioid hyperalgesia
- opioid for cancer and non-cancer treatment
- acute and chronic pain
- CNS disorders
- natural and synthetic compounds
