Novel Antinociceptive Agent against Persistent Pain
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 13000
Special Issue Editor
Interests: pain pharmacology; chronic pain; inflammatory pain; chemotherapy induced neuropathic pain; trauma-induced neuropathic pain, glial cells; hyperalgesia; allodynia; in vivo approach; in vitro approach; therapeutic agents; pharmacological mechanism
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Special Issue Information
Dear Colleagues,
Effective pain therapy is one of society’s principal needs. Persistent and neuropathic pain represent a significant clinical problem and, as chronic conditions, can cause distress and seriously affect a patient’s quality of life. This condition is often refractory to conventional therapy. Analgesics that are used to treat different persistent pain conditions are usually marked by the onset of a several side-effects, and the great majority of patients obtain only partial relief. Therefore, the necessity of new analgesics is clear. Medicinal chemistry is continuously called to face the novel challenges that arise from the steady trickle of scientific breakthroughs to discover new, increasingly safe and effective drugs. This Special Issue of Molecules welcomes previously unpublished manuscripts covering all aspects of pharmacology and chemistry of antinociceptive drugs, in particular the development of novel pain-relieving molecules which are active against different persistent pain conditions.
Dr. Laura Micheli
Guest Editor
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Keywords
- Chronic pain
- Drug development
- Glial cells
- Inflammatory pain
- Medicinal chemistry
- Neuropathic pain
- Pain
- Pharmacodynamics
- Visceral pain
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