New Strategies for the Synthesis and Modification of Peptides and Proteins

Dear Colleagues,

The ability to synthesize peptides and proteins and site-specifically decorate them with a multitude of chemical agents has revolutionized research in the life sciences, allowing the preparation of sophisticated molecular tools and paving the way to countless applications, especially in biomedicine. The research field highlighted in this Special Issue is fervent and in continuous development, leading—in a few decades—to an impressive expansion of the portfolio of chemistries available to synthesize and selectively modify peptides and proteins.

This Special Issue is intended to offer a showcase for presenting novel and straightforward chemical and enzymatic methods allowing protein and peptide synthesis and/or modification and showing the results of research studies performed using these synthetic or semi-synthetic biomolecules. Modifications of interest include, but are not limited to, post-translational modifications, dyes, imaging probes, drugs, polymers and unnatural amino acids. We are also interested in the discussion of innovative strategies for conjugating peptides/proteins to biomaterials and nanoparticles. As a consequence, the applications of interest are not limited to biomedicine but we are also expecting papers reporting exciting results in biomaterial and biosensor science, chemical biology and structural biology. All types of contributions, such as research or review articles, covering the topic area are welcome.

Dr. Luca D. D'Andrea
Dr. Lucia De Rosa
Guest Editors

Manuscript Submission Information

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