(Poly)phenols: Metabolism and Health

Dear Colleagues,

Most polyphenols cannot be absorbed as they are but need some prior structural modification. The absorption of a minimal part of the ingested polyphenols occurs in the first gastro-intestinal tract, whereas the largest part reaches the colon, where polyphenolic compounds are metabolized by the host microbiota. Polyphenol colonic catabolites are possible biologically active molecules, although their production is strictly related to gut composition, responsible for an important interindividual variability.

The understanding of polyphenol–gut microbiota interactions and the gut microbial bioconversion capability could provide more insight into the human metabolism and the bioavailability of bioactive polyphenols and represents an essential step to further investigate the potential health benefits of polyphenols and their derived metabolites. With the support of Molecules, this Special Issue welcomes manuscripts from human, animal, and in vitro studies on the metabolism of polyphenols and their implication in health and disease prevention.

Dr. Letizia Bresciani
Dr. Anna Tresserra-Rimbau
Guest Editors

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