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Recent Developments in the Production and Application of Biosurfactants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 2672

Special Issue Editors


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Guest Editor
Department of Colloid and Lipid Science, Faculty of Chemistry, Gdańsk University of Technology, ul. Narutowicza 11/12, 80-233 Gdańsk, Poland
Interests: ionic liquids; predictive modelling; environmental fate; rhamnolipids; digestion; bile salts
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Assistant Guest Editor
Department of Colloid and Lipid Science, Faculty of Chemistry, Gdańsk University of Technology, ul. Narutowicza 11/12, 80-233 Gdańsk, Poland
Interests: in vitro digestion; in vitro digestion models; biosurfactants; colloids

Special Issue Information

Dear Colleagues,

Microbial biosurfactants, especially rhamnolipids, have found use in a wide variety of applications, from cosmetic and detergent products, to drug delivery and environmental protection and remediation. With their potential environmentally friendly and ecological source, low toxicity, and high stability at different conditions, the continued quest for better targeted production methods as well as novel applications remain a current topic. Therefore, this Special Issue will be devoted to novel developments in the production and design of microbial biosurfactants, and new and insightful applications.

Dr. Christian Jungnickel
Guest Editor

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Keywords

  • biosurfactants
  • rhamnolipids
  • biosurfactant application
  • biosurfactant production
  • green chemistry

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Published Papers (1 paper)

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Research

17 pages, 3432 KiB  
Article
Towards Rational Biosurfactant Design—Predicting Solubilization in Rhamnolipid Solutions
by Ilona E. Kłosowska-Chomiczewska, Adrianna Kotewicz-Siudowska, Wojciech Artichowicz, Adam Macierzanka, Agnieszka Głowacz-Różyńska, Patrycja Szumała, Krystyna Mędrzycka, Elżbieta Hallmann, Elena Karpenko and Christian Jungnickel
Molecules 2021, 26(3), 534; https://doi.org/10.3390/molecules26030534 - 20 Jan 2021
Cited by 6 | Viewed by 2349
Abstract
The efficiency of micellar solubilization is dictated inter alia by the properties of the solubilizate, the type of surfactant, and environmental conditions of the process. We, therefore, hypothesized that using the descriptors of the aforementioned features we can predict the solubilization efficiency, expressed [...] Read more.
The efficiency of micellar solubilization is dictated inter alia by the properties of the solubilizate, the type of surfactant, and environmental conditions of the process. We, therefore, hypothesized that using the descriptors of the aforementioned features we can predict the solubilization efficiency, expressed as molar solubilization ratio (MSR). In other words, we aimed at creating a model to find the optimal surfactant and environmental conditions in order to solubilize the substance of interest (oil, drug, etc.). We focused specifically on the solubilization in biosurfactant solutions. We collected data from literature covering the last 38 years and supplemented them with our experimental data for different biosurfactant preparations. Evolutionary algorithm (EA) and kernel support vector machines (KSVM) were used to create predictive relationships. The descriptors of biosurfactant (logPBS, measure of purity), solubilizate (logPsol, molecular volume), and descriptors of conditions of the measurement (T and pH) were used for modelling. We have shown that the MSR can be successfully predicted using EAs, with a mean R2val of 0.773 ± 0.052. The parameters influencing the solubilization efficiency were ranked upon their significance. This represents the first attempt in literature to predict the MSR with the MSR calculator delivered as a result of our research. Full article
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