Frontier of Protein Crystallography II

Dear Colleagues,

Protein crystallography continues to develop vigorously and today there are over 120,000 structures deposited at the Protein Data Bank (PDB), 90% of which are from X-ray data. The technological developments behind this rapid growth involve all crucial steps of the pipeline “from gene to structure”: from the developments of wet lab technologies, including recombinant DNA techniques, protein purification, and crystallization; to innovative hardware technology, for example, brilliant light sources such as synchrotrons and X-ray free-electron lasers (XFEL) together with high-frame-rate and ultra-sensitive detectors. An important impetus to protein crystallography has also been provided by soft technology: theoretical foundations, computational algorithms, and software development. The bio-crystallography integrated with cryo-electron microscopy is a major research trend in structural biology.

Our First volume is successful and attracts a lot of attention. This research field is still full of possibilities. This Special Issue will focus on covering frontier technologies and methodologies in protein crystallography, as well as their novel applications.

Prof. Dr. Silvano Geremia
Guest Editor

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