Development of Chromatographic Methods Hyphenated Systems to Mass Spectrometry
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: closed (30 October 2022) | Viewed by 2609
Special Issue Editors
Interests: separation science; liquid chromatography; mass spectrometry; sample preparation; miniaturized separation systems; sorbent development
Special Issue Information
Dear Colleagues,
The separation techniques, especially liquid chromatography (LC), have been widely used over the last years, and they are essential in many laboratories being used in the routine analysis or else for new molecule discovery. Undoubtedly, the hyphenation of the mass spectrometry systems (MS) with LC equipment, and the improvement on the LC-MS systems technology support the extensive use of these separation techniques.
The potential of separation techniques hyphenated with the MS system afforded the determination of trace level content in complex samples. The LC-MS methodologies brought considerable contributions to different scientific fields such as environmental, pharmaceutical, clinical, food and forensic fields.
The consolidation of separation science hyphenated to mass spectrometry also contributed to the miniaturization of separation systems development and reduce all analytical processes. However, the complexity of some samples and the need to investigate thousands of compounds exceeds the capacity of just one separation step. Thus, multidimensional liquid chromatography methods could provide a way to clarify these very complex matrixes.
In this Special Issue, we welcome original research articles and reviews on the development of LC-MS methodologies (conventional, miniaturized, or multidimensional) for all science fields, considering that the LC-MS method was essential to problem investigation.
Prof. Dr. Andrea Rodrigues Chaves
Dr. Boniek Gontijo Vaz
Guest Editors
Manuscript Submission Information
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Keywords
- separation science
- liquid chromatography
- mass spectrometry
- sample preparation
- miniaturized separation systems
- sorbent development
