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Nutrients
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Nutritionally Relevant Constituents and Biological Activity of Novel Foods
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Nutritionally Relevant Constituents and Biological Activity of Novel Foods

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 700

Special Issue Editors

Dr. Valentina Melini

E-Mail Website
Guest Editor
CREA-Research Centre for Food and Nutrition, Rome, Italy
Interests: bioactive compounds; phenolic compounds; antioxidants; cereals; pseudocereals; functional foods; novel foods; HPLC; analytical methods
Special Issues, Collections and Topics in MDPI journals
Dr. Francesca Melini

E-Mail
Guest Editor
CREA Research Centre for Food and Nutrition, Via Ardeatina 546, I-00178 Roma, Italy
Interests: food quality; pseudocereals; legumes; cereals; bioactive compounds; gluten-free products; food by-products; fermented foods
Special Issues, Collections and Topics in MDPI journals
Dr. Francesca Luziatelli

E-Mail Website
Guest Editor
Department for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), Tuscia University, Via S. C. De Lellis snc, 01100 Viterbo, Italy
Interests: food quality; metabolism; metabolic engineering; metagenomics; microbial communities

Special Issue Information

Dear Colleagues,

Due to innovation and globalization, an increasing number of foodstuffs have entered the European Union (EU) market and contributed to meeting the growing demands of consumers for dietary alternatives which are good for the planet and good for our health. Foodstuffs produced with new technologies or derived from new sources, newly synthesized/isolated compounds, and traditional foods from non-EU countries that were not consumed to a significant degree within the EU before 15 May 1997 are among the main categories of novel foods (NF).

The aim of this Special Issue is to bring together original research papers or reviews on novel foods, with special attention given to nutritional information, bioactive compounds and antinutritional factors, proposed uses and use levels, allergenicity, anticipated intake and ADME. Since several novel foods have been investigated for their potential health benefits, in terms of antioxidant activity, cardiovascular disease prevention, modulation of immune response and prevention of age-related cognitive decline, studies on these aspects are also welcome.

Dr. Valentina Melini
Dr. Francesca Melini
Dr. Francesca Luziatelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • novel foods
  • grains
  • insects
  • microalgae
  • mushrooms
  • fermented foods
  • UV-treated foods
  • alternative proteins
  • novel carbohydrates
  • sugar substitutes
  • fibers
  • human identical milk oligosaccharides
  • quality and compositional data
  • nutritionally relevant constituents
  • biological activity
  • bioavailability
  • stability
  • consumers acceptance

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Published Papers (1 paper)

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Research

14 pages, 2717 KiB  
Article
Effect of Purified Resveratrol Butyrate Ester Monomers against Hypertension after Maternal High-Fructose Intake in Adult Offspring
by You-Lin Tain, Chih-Yao Hou, Hong-Tai Tzeng, Shu-Fen Lin, Guo-Ping Chang-Chien, Wei-Chia Lee, Kay L. H. Wu, Hong-Ren Yu, Julie Y. H. Chan and Chien-Ning Hsu
Nutrients 2024, 16(18), 3132; https://doi.org/10.3390/nu16183132 - 17 Sep 2024
Abstract
Background: Offspring hypertension arising from adverse maternal conditions can be mitigated through dietary nutritional supplementation, including resveratrol. Previously, we identified derivatives of resveratrol butyrate ester (RBE), specifically 3,4′-di-O-butanoylresveratrol (ED2) and 3-O-butanoylresveratrol (ED4), demonstrating their superior antioxidant capabilities compared to RBE itself. This study [...] Read more.
Background: Offspring hypertension arising from adverse maternal conditions can be mitigated through dietary nutritional supplementation, including resveratrol. Previously, we identified derivatives of resveratrol butyrate ester (RBE), specifically 3,4′-di-O-butanoylresveratrol (ED2) and 3-O-butanoylresveratrol (ED4), demonstrating their superior antioxidant capabilities compared to RBE itself. This study sought to assess the protective impact of maternal supplementation with ED2 or ED4 on offspring hypertension in a rat model subjected to a high-fructose (HF) diet during pregnancy and lactation. Methods: Female Sprague–Dawley rats were distributed into distinct dietary groups throughout pregnancy and lactation: (1) standard chow; (2) HF diet (60%); (3) HF diet supplemented with ED2 (25 mg/L); and (4) HF diet supplemented with ED4 (25 mg/L). Male offspring were euthanized at the age of 12 weeks. Results: The maternal HF diet induced hypertension in the offspring, which was mitigated by perinatal supplementation with either ED2 or ED4. These protective effects were attributed to the antioxidant properties of ED2 and ED4, resulting in an increased availability of nitric oxide (NO). Additionally, supplementation with ED2 was connected to an increased abundance of Bifidobacterium and Clostridium genera, which was accompanied by a decrease in Angelakisella and Christensenella. On the other hand, ED4 supplementation shielded rat offspring from hypertension by elevating concentrations of short-chain fatty acids (SCFAs) and their receptors while reducing trimethylamine-N-oxide (TMAO) levels. Conclusions: These findings highlight the potential of purified RBE monomers, ED2 and ED4, as preventive measures against hypertension resulting from a maternal high-fructose diet. Further research is warranted to explore their clinical applications based on these promising results. Full article
(This article belongs to the Special Issue Nutritionally Relevant Constituents and Biological Activity of Novel Foods)
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