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Effect of Protein and Peptide Supplementation on Physical Performance and...
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Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition)

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Proteins and Amino Acids".

Deadline for manuscript submissions: closed (25 May 2024) | Viewed by 2585

Special Issue Editors

Dr. Lei Zhao

E-Mail Website
Guest Editor
Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
Interests: protein; bioactive peptide; nutraceutical and functional food; phytochemicals; bioavailability
Special Issues, Collections and Topics in MDPI journals
Dr. Liang Zhao

E-Mail Website
Guest Editor
Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
Interests: antioxidant activity;natural product chemistry;non-alcoholic fatty liver disease;retinal degeneration;apoptosis;polyphenols;ethanol;gut microbiology;electrocardiogram;flavonoids
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As one of the major nutrient groups in the human diet, food proteins play an important role in human health and wellbeing. In addition to providing a source of energy and amino acids for the synthesis of body proteins, food proteins play vital roles in many physiological processes, such as structure, function, synthesis, restoration, and transportation. Protein hydrolysates composed of small peptides are absorbed more rapidly than free amino acids and intact proteins and can improve protein retention in the human body. Protein and peptide supplementation are also proposed as an effective dietary strategy in prevention and/or adjunctive treatment of various lifestyle- and ageing-related diseases (e.g., type 2 diabetes, hypertension, dyslipidemia, cancer, liver disease, sarcopenia, and cardiovascular disease).

Considering the success of the previous Special Issue entitled “Effect of Protein and Peptide Supplementation on Physical Performance and Health Status”, we are pleased to announce that we are launching a second volume on this topic. The planned Special Issue entitled “Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition)” will include original studies and review articles focusing on the impact of proteins, peptides, and products enriched with these supplements on human physical performance and health status, as well as their absorption, distribution, metabolism, and excretion.

Dr. Lei Zhao
Dr. Liang Zhao
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • protein
  • peptide
  • protein hydrolysates
  • health benefits
  • physical performance
  • absorption
  • metabolism

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Published Papers (2 papers)

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Research

10 pages, 1280 KiB  
Article
Effect of Oral Skim Milk Administration on Skeletal Muscle Protein Synthesis after Total Gastrectomy in Rat
by Atsushi Sawada, Ryo Takagi, Junya Takegaki, Naoki Fukao, Koki Okumura and Satoshi Fujita
Nutrients 2024, 16(15), 2390; https://doi.org/10.3390/nu16152390 - 23 Jul 2024
Viewed by 562
Abstract
Leucine is a branched-chain amino acid that is present in protein, and it is an essential factor in activating the mechanistic target of the rapamycin complex 1 signaling pathway and increasing muscle protein synthesis. However, the loss of digestive function after total gastrectomy [...] Read more.
Leucine is a branched-chain amino acid that is present in protein, and it is an essential factor in activating the mechanistic target of the rapamycin complex 1 signaling pathway and increasing muscle protein synthesis. However, the loss of digestive function after total gastrectomy leads to impaired protein absorption, potentially failing to stimulate muscle protein synthesis. Therefore, this study aimed to investigate whether muscle protein synthesis is enhanced by oral skim milk administration after total gastrectomy. Male Sprague Dawley rats were divided into total gastrectomy (TG) and sham surgery (S) groups. After five weeks postoperatively, we orally administered skim milk to achieve 3.1 g protein/kg body weight and collected blood and gastrocnemius muscle. The gastrocnemius muscle weight was significantly lower in the TG group than in the S group (p < 0.05). The increase in plasma leucine concentration was significantly lower in the TG group than in the S group (p < 0.05). The skeletal muscle protein synthesis and the phosphorylation of p70S6K and 4E-BP1 showed a similar increase in both groups. Even after TG, muscle protein synthesis was stimulated by consuming skim milk, accompanied by a sufficient rise in plasma leucine concentration. Full article
(This article belongs to the Special Issue Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition))
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14 pages, 3357 KiB  
Article
Antibacterial Effect of Sesame Protein-Derived Peptides against Escherichia coli and Staphylococcus aureus: In Silico and In Vitro Analysis
by Zehui Zhu, Fei Pan, Ou Wang, Liang Zhao and Lei Zhao
Nutrients 2024, 16(1), 175; https://doi.org/10.3390/nu16010175 - 4 Jan 2024
Cited by 1 | Viewed by 1727
Abstract
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins with pepsin, trypsin, and chymotrypsin was performed with the online server BIOPEP-UWM. The CAMPR3 online [...] Read more.
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins with pepsin, trypsin, and chymotrypsin was performed with the online server BIOPEP-UWM. The CAMPR3 online server was used to predict the antimicrobial effect of peptides. The ToxinPred, PepCalc, and AllergenFP tools were utilized to forecast the physicochemical properties, toxicity, and allergen of the peptides. Molecular docking analysis showed that six cationic antimicrobial peptides could directly interact with the key sites of dihydropteroate synthase, whereas Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg exhibited the strongest binding affinity. In vitro antibacterial experiment showed the minimum inhibitory concentration (MIC) of Ser-Thr-Ile-Arg against Escherichia coli and Staphylococcus aureus was 1024 and 512 µg/mL, respectively. Meanwhile, MIC of Ala-Gly-Gly-Val-Pro-Arg against both bacterial species was 512 µg/mL. Our results suggest that peptides from sesame possess the ability to potentially hinder bacterial activity. Full article
(This article belongs to the Special Issue Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition))
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