The Role of Fatty Acids in Diet, Gut Microbiota, and Metabolic Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 15 January 2025 | Viewed by 134
Special Issue Editor
Interests: cancer biology; nutritional biochemistry; nutrition and cancer; gut microbiome and metabolites; phytonutrients and chronic disease prevention
Special Issue Information
Dear Colleagues,
This Special Issue explores the critical role that dietary fatty acids play in modulating gut microbiota and metabolites and their subsequent impact on metabolic health. The gut microbiota and their metabolites significantly influence host metabolism, immune function, and health. Dietary fatty acids, including saturated fats, monounsaturated fats, and polyunsaturated fats (PUFAs), affect the composition and function of gut microbiota and their metabolites in various manners.
Key Topics Covered:
- Types of Dietary Fatty Acids:
Saturated Fatty Acids (SFAs): typically found in animal fats and some plant oils, SFAs can alter the gut microbiota composition, often leading to reduced microbial diversity and increased inflammation, contributing to metabolic disorders like obesity and insulin resistance.
Monounsaturated Fatty Acids (MUFAs): present in olive oil and avocados, MUFAs are associated with beneficial effects on gut microbiota, promoting microbial diversity and reducing inflammation.
Polyunsaturated Fatty Acids (PUFAs): Including omega-3 and omega-6 fatty acids, PUFAs play a crucial role in maintaining gut health. Omega-3 fatty acids, found in fish oil and flaxseed, have anti-inflammatory properties and affect gut microbiota metabolites. Conversely, excessive omega-6 fatty acid intake, common in processed foods, can promote inflammation and negatively affect gut health.
- Topics of health implications:
The research topics on health implications can cover various aspects, which are briefly outlined below. These topics focus on the regulation of chronic diseases such as obesity, metabolic syndrome, inflammatory diseases, cardiovascular diseases, stroke, hepatic diseases, renal diseases, and more.
Conclusion:
This Special Issue emphasizes the importance of dietary fatty acids in the modulation of gut microbiota and metabolites and influencing metabolic health. It underscores the need for balanced dietary fat intake to promote a healthy gut microbiome and reduce the risk of metabolic and inflammatory diseases.
Prof. Dr. Feng-Yao Tang
Guest Editor
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Keywords
- dietary fatty acids
- gut microbiota
- metabolites
- metabolic health
- chronic diseases
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