Polyphenols and Cancer Prevention
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".
Deadline for manuscript submissions: closed (15 April 2022) | Viewed by 13531
Special Issue Editor
Interests: breast cancer; natural compounds; polyphenols; antioxidants; chemoprevention; cancer stem cells; chemotherapy; tumor resistance; metastasis; targeted therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Polyphenols are a heterogeneous and abundant naturally occurring compounds which are present in a variety of plants, and their food derivatives, like vegetables, trees, fruits, whole grains, legumes, beverages, oils, nuts, algae, and even fungi. These bioactive molecules, and their metabolites, have been extensively addressed in research by their protective role against chronic diseases including cancer. Such ability of polyphenolic compounds on cancer prevention is attributed to a wide range of activities (including antioxidant capacity, modulation of numerous signaling pathways like TGFβ/SMADs, PI3K/Akt/mTOR, Wnt, or NF-κB, or interaction with microbiota) that promote genome stability, strengthen immune system, reduce inflammation, cell senescence, among other responses that positively influence in the prevention of cancer appearance.
The topics of this special issue of Nutrients include, although not limited to, relevant research of plant polyphenols, as well as their metabolites, food derivatives, and extracts, on modulating (positively/negatively) the effects mediated by any factor that may promote or prevent cancer (environment, lifestyle, genetic predisposition…), including alterations on immune system, tissue microenvironment, and interaction with microbiota. Polyphenols from different origin, other than plants, will also be considered.
Dr. Sergio Granados-Principal
Guest Editor
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Keywords
- polyphenols
- metabolites
- bioactive compounds
- mediterranean diet
- cancer prevention
- risk factors
- immunomodulation
- tissue microenvironment
- microbiota
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