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Nutrients
Special Issues
Cardiovascular Disease, Immune System and Nutrition
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Cardiovascular Disease, Immune System and Nutrition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (22 August 2023) | Viewed by 3577

Special Issue Editor

Dr. Annet Kirabo

E-Mail Website
Guest Editor
Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA
Interests: cardiovascular disease; hypertension; dendritic cells; neo-antigens; isolevuglandins; microbiome

Special Issue Information

Dear Colleagues,

This Special Issue was proposed to clarify the immunotherapeutic approaches used in cardiovascular disease.

Cardiovascular disease is one of the most common throughout the world. With the increase in life stress and the diversification of diet, more and more people, including younger groups, are vulnerable to it. It is well established that innate and adaptive immune responses have an essential role in the development and progression of many cardiovascular diseases. In recent years, significant progress in understanding the impact of diets and nutrient interventions on influencing the immune system and cardiovascular disease has been made.

This Special Issue of Nutrients welcomes original research articles, animal and clinical studies, and review articles on the current state of research.

Dr. Annet Kirabo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular disease
  • hypertension
  • immune system
  • oxidative stress

Published Papers (1 paper)

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Review

16 pages, 4711 KiB  
Review
Glycocalyx–Sodium Interaction in Vascular Endothelium
by Lawrence Fred Sembajwe, Abdul M. Ssekandi, Agnes Namaganda, Haruna Muwonge, Josephine N. Kasolo, Robert Kalyesubula, Annettee Nakimuli, Mwesigwa Naome, Kaushik P. Patel, Sepiso K. Masenga and Annet Kirabo
Nutrients 2023, 15(13), 2873; https://doi.org/10.3390/nu15132873 - 25 Jun 2023
Cited by 3 | Viewed by 3376
Abstract
The glycocalyx generally covers almost all cellular surfaces, where it participates in mediating cell-surface interactions with the extracellular matrix as well as with intracellular signaling molecules. The endothelial glycocalyx that covers the luminal surface mediates the interactions of endothelial cells with materials flowing [...] Read more.
The glycocalyx generally covers almost all cellular surfaces, where it participates in mediating cell-surface interactions with the extracellular matrix as well as with intracellular signaling molecules. The endothelial glycocalyx that covers the luminal surface mediates the interactions of endothelial cells with materials flowing in the circulating blood, including blood cells. Cardiovascular diseases (CVD) remain a major cause of morbidity and mortality around the world. The cardiovascular risk factors start by causing endothelial cell dysfunction associated with destruction or irregular maintenance of the glycocalyx, which may culminate into a full-blown cardiovascular disease. The endothelial glycocalyx plays a crucial role in shielding the cell from excessive exposure and absorption of excessive salt, which can potentially cause damage to the endothelial cells and underlying tissues of the blood vessels. So, in this mini review/commentary, we delineate and provide a concise summary of the various components of the glycocalyx, their interaction with salt, and subsequent involvement in the cardiovascular disease process. We also highlight the major components of the glycocalyx that could be used as disease biomarkers or as drug targets in the management of cardiovascular diseases. Full article
(This article belongs to the Special Issue Cardiovascular Disease, Immune System and Nutrition)
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