MicroRNAs in Ocular Infections: Pathogenesis, Diagnostics, and Therapeutics
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: 31 January 2025 | Viewed by 147
Special Issue Editor
Interests: microRNAs in corneal biology; ocular immunity; sensory innervation; neuroimmune interaction; bacterial keratitis; other corneal and ocular diseases
Special Issue Information
Dear Colleagues,
MicroRNAs (miRNAs) are a class of non-coding RNA molecules, approximately 22 nucleotides in length, that negatively regulate gene expression by binding complementary to the 3’ untranslated regions (UTRs) of target mRNAs, including the promotion of mRNA degradation and/or translation inhibition. In recent years, research has revealed that miRNAs play a crucial role in the development and homeostasis of the cornea, as well as the pathogenesis of ocular infectious diseases. miRNAs can influence the progression of ocular infectious diseases by regulating host immune responses, inflammatory reactions, sensory innervation, neuroimmune interaction, and replication of pathogens, as well as host–pathogen interactions. At the same time, researchers have also found that miRNAs have significant application potential in the diagnosis and treatment of ocular infectious diseases.
This Special Issue welcomes original research papers, review articles, case reports, etc. Submissions should cover the latest research findings and progress in the role of miRNAs in the pathogenesis, diagnostics, and therapeutics of ocular infections. We hope that this Special Issue will provide a platform for researchers in the field of ophthalmology to exchange ideas and promote the development of miRNA research and clinical applications in ocular infectious diseases.
Dr. Shunbin Xu
Guest Editor
Manuscript Submission Information
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Keywords
- microRNAs
- ocular infection
- diagnosis
- pathogenesis
- therapeutics
- microbial keratitis
- bacterial keratitis
- fungal keratitis
- viral keratitis
- herpes simplex keratitis
- endophthalmitis
- ocular immunity
- neuroimmune interaction
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