Transmission and Pathogenesis of Viral Infectious Disease

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 4030

Special Issue Editor


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Guest Editor
Division of High-Risk Pathogen, Bureau of Infectious Disease Diagnosis Control, Korea Diseases Control and Prevention Agency, Cheongju 28159, Republic of Korea
Interests: viral infection; molecular detection; pathogenesis; phylogenetic analysis

Special Issue Information

Dear Colleagues,

The continuous outbreak of viral infectious diseases such as COVID-19 reminds us of humanity’s endless scientific developments. In addition, for various reasons, the emergence of new viruses and the expansion of the region from the narrow transmission of viruses to international transmission, such as monkeypox viruses, is resulting in very threatening attacks on humans. The newest virus variant is spreading, expanding the area of local infection and impacting high-risk groups vulnerable to infection. Identifying the occurrence of these viral infections, monitoring transmission and continuous observation of mutations can act as essential factors for future human survival.

This Special Issue aims to discuss the accurate diagnosis of various viral infections and the results of molecular epidemiological studies to predict infection through virus gene detection inside vectors, identify the source of infection and identify transmission routes.

Dr. Yoon-Seok Chung
Guest Editor

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Keywords

  • viruses
  • transmission clusters
  • molecular epidemiology
  • phylogenetic analysis
  • pathogenesis
  • viral infectious disease

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Published Papers (1 paper)

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Research

9 pages, 1090 KiB  
Communication
Re-Emergence of HMPV in Gwangju, South Korea, after the COVID-19 Pandemic
by Sun-Ju Cho, Sun-Hee Kim, Hongsu Lee, Yeong-Un Lee, Jeongeun Mun, Sujung Park, Jungwook Park, Ji-Su Park, Kwangho Lee, Cheong-mi Lee, Jinjong Seo, Yonghwan Kim and Yoon-Seok Chung
Pathogens 2023, 12(10), 1218; https://doi.org/10.3390/pathogens12101218 - 4 Oct 2023
Cited by 7 | Viewed by 3455
Abstract
The non-pharmaceutical interventions implemented to prevent the spread of COVID-19 have affected the epidemiology of other respiratory viruses. In South Korea, Human metapneumovirus (HMPV) typically occurs from winter to the following spring; however, it was not detected for two years during the COVID-19 [...] Read more.
The non-pharmaceutical interventions implemented to prevent the spread of COVID-19 have affected the epidemiology of other respiratory viruses. In South Korea, Human metapneumovirus (HMPV) typically occurs from winter to the following spring; however, it was not detected for two years during the COVID-19 pandemic and re-emerged in the fall of 2022, which is a non-epidemic season. To examine the molecular genetic characteristics of HMPV before and after the COVID-19 pandemic, we analyzed 427 HMPV-positive samples collected in the Gwangju area from 2018 to 2022. Among these, 24 samples were subjected to whole-genome sequencing. Compared to the period before the COVID-19 pandemic, the incidence rate of HMPV in 2022 increased by 2.5-fold. Especially in the age group of 6–10 years, the incidence rate increased by more than 4.5-fold. In the phylogenetic analysis results, before the COVID-19 pandemic, the A2.2.2 lineage was predominant, while in 2022, the A2.2.1 and B2 lineage were observed. The non-pharmaceutical interventions implemented after COVID-19, such as social distancing, have reduced opportunities for exposure to HMPV, subsequently leading to decreased acquisition of immunity. As a result, HMPV occurred during non-epidemic seasons, influencing the age distribution of its occurrences. Full article
(This article belongs to the Special Issue Transmission and Pathogenesis of Viral Infectious Disease)
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