Replication and Pathogenesis of Influenza Viruses

Dear Colleagues,

Influenza viruses are able to cause seasonal influenza epidemics and even pandemics (e.g., 2009 Influenza A virus (novel H1N1)). Even with the availability of seasonal influenza vaccines and antiviral agents, seasonal epidemics caused by influenza viruses still result in 3 to 5 million severe cases, particularly among infants and older adults, and thousands of deaths globally each year. Therefore, more studies on the influenza viral life cycle, including cross-species transmission, are necessary.

The Special Issue will highlight recent advances in the mechanistic understanding of the replication and pathogenesis of influenza viruses. Both reviews and research articles are welcome. Topics can include but are not limited to the following:

1. Expressional regulation and functional characterization of various viral gene products;
2. Replication and pathogenesis of various influenza viruses;
3. Interactions between influenza viruses and other pathogens (other viruses or bacteria);
4. Interactions between influenza viruses and host cells, including antiviral immune responses;
5. Countermeasures to combat influenza viral infection (e.g., vaccine development and antiviral agents).

Dr. Shih-Yen Lo
Guest Editor

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