Immune Response of the Host and Vaccine Development

Dear Colleagues,

Vaccines are the key element to efficiently control infectious diseases. They offer what other treatments cannot accomplish—protection. Recently, during the COVID-19 pandemic, thanks to the enormous commitment of researchers from around the world, tremendous progress has been achieved in vaccine development, especially in the field of virus-vectored and mRNA vaccines. Nonetheless, beyond the pandemic, various infectious diseases that we have been aware of for a long time remain dangerous. Successful immunoprophylactic strategies directed against multiple viruses, bacteria, and parasites are still desperately needed. Those pathogens elicit different immune mechanisms in their hosts. Immunization efficacy strictly depends on the proper activation of the host immune system, and therefore, these two aspects of vaccine research should be investigated in parallel. We hope that this Special Issue will offer new insights into the field and help to combine the knowledge on the immune response of the host with vaccine development.

We invite our colleagues in science to submit original as well as review articles related to:
•    Immune response to pathogen infections;
•    Vaccine antigen identification and validation of its vaccine potential;
•    Vaccine formulations: whole pathogen, subunit, vectored, DNA, mRNA;
•    Vaccine delivery, i.a., edible vaccines;
•    Adjuvant use;
•    Host response to vaccination.

Dr. Ewa Długosz
Dr. Agnieszka Wesołowska
Guest Editors

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