Medicinal Chemistry of Metal Complexes: Design, Synthesis and Evaluation
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 25 June 2025 | Viewed by 68
Special Issue Editors
Interests: coordination complexes; inorganic biochemistry; medicinal chemistry; biological activity; drug design
Interests: antitumor drugs; molecular oncology; drug targeting; medicinal chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: bioactive compounds; antioxidants; phytochemistry; food chemistry; functional food
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Special Issue Information
Dear Colleagues,
Metal-based drugs and metal complexes continue to be of great interest in medicinal chemistry due to their diversity in biological application. They can play a key role in various biochemical processes in living beings and are essential for catalysis, photochemistry, etc., in biological systems.
Throughout history, metal-based drugs have been used, but the discovery of cisplatin was a breakthrough moment that motivated researchers to design and synthesize more metal complexes for use in biological treatment. Platinum-based drugs, especially cisplatin, are undoubtedly the most commonly used metal complexes in the treatment of cancer, but a large number of complex compounds based on other metals (palladium, gold, ruthenium, silver, tin, rhodium, etc.) are also used as antitumor drugs.
This Special Issue, “Medicinal Chemistry of Metal Complexes: Design, Synthesis and Evaluation”, focuses on the growing knowledge in coordination chemistry that is crucial for the design of new compounds for therapeutic and diagnostic use, such as in cancer, diabetes, Parkinson’s and Alzheimer’s disease therapy, or any other use of metal-based drugs as possible medicines for a biological targets in living organisms. The evaluation can additionally refer to any interesting features of metal complexes such as their optical, magnetic, electrical, crystal or even nanostructure properties.
Here, we welcome original research articles and reviews. It is of great value to clearly organize the presented data, so that the article is easy to read even for researchers outside this field.
We look forward to receiving your contributions.
Dr. Bojana B. Zmejkovski
Prof. Dr. Goran Kaluđerović
Dr. Nebojša Pantelić
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metal complexes
- medicinal chemistry
- bioinorganic chemistry
- coordination chemistry
- organometallics
- metal-based drugs
- biological activity
- toxicology
- biomedical application
- drug delivery
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