The Role of Bioactive Compounds in the Prevention of Rheumatoid Arthritis
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 15 July 2024 | Viewed by 2233
Special Issue Editor
Interests: bioactive compounds; phytochemicals; natural products as health promoters; chronic diseases; circular economy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Rheumatoid arthritis (RA) is a multifactorial disease that involves both genetic predisposition and environmental components. In 2019, there were 18 million RA patients worldwide. Aproximately 70% of RA patients are women, and 55% are older than 55 years. Thirteen million people with rheumatoid arthritis experience severity levels (moderate or severe) that could benefit from rehabilitation. RA is characterized by chronic inflammation of the synovial membrane that lines the joints, damage to the cartilage, and erosion of the bone. Bioactive compounds are dietary ingredients that provide beneficial health effects to functional foods and nutraceuticals. These compounds exhibit antioxidant and anti-inflammatory activities, as well as additional preventative properties. Bioactive compounds found in natural food products can control arthritic inflammation through multiple pathways, for example the inhibition of effector molecules (e.g., cytokines and chemokines), induction of anti-inflammatory mediators (e.g., IL-4, IL-10), regulation of the Th17/Treg balance, and modulation of osteo-immune cross-talk.
Dr. Luís Manuel Lopes Rodrigues Da Silva
Guest Editor
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Keywords
- bioactive compounds
- functional foods
- nutraceuticals
- rheumatoid arthritis
- anti-inflamatory activity
- anti-inflammatory mediators