Brain Theranostics: Focus on Drug Delivery and Outcomes
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 12822
Special Issue Editor
Interests: neurodevelopmental biology; neurodegenerative disorders; drug delivery; bioimaging; toxicology; biomarker discovery
Special Issue Information
Dear Colleagues,
Brain theranostics is an emerging research field, integrating “therapeutics” and “diagnostics”. The theranostics approach provides new modalities to improve the diagnostic specificity of brain diseases and to develop and investigate the efficacy of newly developed or repurposed therapeutic compounds, and of targeted and controlled drug delivery schemes. Such a promising field involves concepts associated with the design of probes to image brain diseases, the development of non-invasive bioimaging modalities with high sensitivity and specificity to track biomarkers, the identification of disease-associated mechanisms, and the engineering of delivery platforms such as nanoformulations and extracellular vesicles to improve delivery across the blood–brain barrier (BBB) for effective treatment outcomes.
The objective of this Special Issue is to invite leading experts in the fields of neurodegenerative diseases, neurodevelopmental disorders, neurobehavioral biology, drug-induced neurotoxicity, bioimaging and nanomedicine to discuss their most recent discoveries, and to share their vision for future development in associated topics. Spontaneous submissions are welcome. Both original unpublished research articles and reviews will be considered.
Topics include, but are not limited to:
- New techniques to improve the blood–brain barrier (BBB) penetration of theranostic molecules;
- Sensitive bioimaging modalities for the detection of brain diseases and/or therapeutic efficacy;
- Nanomedicine for the therapy of brain diseases;
- New developments for controlled or targeted drug delivery to the brain;
- Neurodevelopmental neurotoxicity following in utero exposure to therapeutic drugs and new approaches to improve outcomes;
- Neurobehavioral assessments defining brain diseases and therapeutic outcomes;
- Novel mechanisms underlying brain diseases.
Dr. Aditya N. Bade
Guest Editor
Manuscript Submission Information
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Keywords
- brain
- neurodegenerative diseases
- therapeutics
- diagnostics
- nanomedicine
- MRI/SPECT/PET
- blood–brain barrier
- neurotoxicity
- behavioral tests
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