Epigenetic Drug Discovery
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (15 May 2014) | Viewed by 259
Special Issue Editor
Special Issue Information
Dear Colleagues,
There is currently significant interest in the discovery and development of epigenetic drugs for many chronic diseases, including cancer, inflammatory, metabolic and neuro-psychiatric conditions. It is hypothesised that these may modify the transcription of many causative genes implicated in the development and maintenance of such diseases, and hence inhibitors of these proteins may deliver novel disease modifying therapeutics. There are questions, however, around the tolerability or therapeutic index of such agents. In this issue we will discuss the latest developments in both academia and industry.
Prof. Dr. Chas Bountra
Guest Editor
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Keywords
- epigenetics
- drug discovery
- HDACs
- bromodomain inhibitors
- HMT inhibitors
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Related Special Issue
- Epigenetic Therapies and Biomarkers in Pharmaceuticals (6 articles)
