Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Products Derived from Fungi and Their Biological Activities
edited by
submission deadline 30 Nov 2024 | Viewed by 270 | Submission Open
Keywords: fungi; medicinal fungi; fruiting bodies; mycelial cultures; bioactive compounds; pro-health activity; mushroom products; natural therapy; natural medicines
(This special issue belongs to the Section Natural Products)
Advances in Peptide Chemistry and Medicinal Application
edited by
submission deadline 30 Nov 2024 | Viewed by 149 | Submission Open
Keywords: peptide-based compounds; peptidomimetics; drug discovery; drug-like properties; target modulation; structure– activity relationship studies; unnatural amino acids; backbone modifications; antibodies; hydrogels
(This special issue belongs to the Section Medicinal Chemistry)
Innovative Applications and Therapeutic Potential of Cannabinoids submission deadline 30 Nov 2024 | Viewed by 68 | Submission Open
Keywords: cannabis; cannabinoids; cannabidiol; tetrahydrocannabinol; endocannabinoid system; biopharmaceuticals; pharmacology; drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
The 20th Anniversary of Pharmaceuticals—How Artificial Intelligence Is Reshaping Pharmaceuticals Technology
edited by
submission deadline 1 Dec 2024 | 6 articles | Viewed by 9041 | Submission Open
Keywords: drug delivery; drug analysis; pharmaceutical technology; controlled release and sustained release; formula design; artificial intelligence
(This special issue belongs to the Section Pharmaceutical Technology)
Inhibition and Treatment in Adhesion, Migration, Invasion, and Metastasis of Cancer Cells
edited by , and Wioletta Zielińska
submission deadline 13 Dec 2024 | Viewed by 108 | Submission Open
Keywords: migration; metastasis; invasion; tumor progression; cell adhesion; cancer; epithelial– mesenchymal transition; cancer therapy
(This special issue belongs to the Section Medicinal Chemistry)
Last Trends of Antileishmanial Drug Discovery and Development submission deadline 14 Dec 2024 | Viewed by 62 | Submission Open
Keywords: leishmania; drugs; parasitic treatment; visceral leishmaniasis; canine leishmaniasis; drug resistance; drug targets
(This special issue belongs to the Section Medicinal Chemistry)
Anticancer Compounds in Medicinal Plants — In Honour of the 20th Anniversary of Pharmaceuticals submission deadline 15 Dec 2024 | 12 articles | Viewed by 10257 | Submission Open
Keywords: natural products; phytochemicals; cancer; secondary metabolites; medicinal plants
(This special issue belongs to the Section Natural Products)
Natural Pharmacons: Biologically Active Plant-Based Pharmaceuticals 2024 submission deadline 15 Dec 2024 | 4 articles | Viewed by 3961 | Submission Open
(This special issue belongs to the Section Natural Products)
The 20th Anniversary of Pharmaceuticals: Advances in Peptide Drug Design and Development: From Sequences to Drug Candidates
edited by Juliana C. C. Dallagnol and David Chatenet
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1496 | Submission Open
Keywords: peptide-based drugs; drug design; therapeutic peptides; peptide synthesis; structure– activity relationship; peptide drug delivery; bioavailability; formulation strategies; peptide therapeutics
(This special issue belongs to the Section Biopharmaceuticals)
Medicinal Plants: A Natural Approach to Inflammatory Diseases and Conditions Related to Oxidative Stress
edited by and Adriano Araujo
submission deadline 15 Dec 2024 | Viewed by 105 | Submission Open
Keywords: medicinal plants; phytocompounds; natural products; inflammatory diseases; oxidative stress
(This special issue belongs to the Section Natural Products)
Recent Advances in Behavioral Psychopharmacology submission deadline 15 Dec 2024 | Viewed by 33 | Submission Open
Keywords: addiction; behavioral models; behavioral pharmacology; cognition; depression; drug abuse; memory; psychoactive drugs
(This special issue belongs to the Section Pharmacology)
Small Molecules as Antimicrobials 2024
edited by
submission deadline 15 Dec 2024 | Viewed by 20 | Submission Open
Keywords: small molecules; antimicrobials; antivirals; antibacterials; antimycobacterials
(This special issue belongs to the Section Medicinal Chemistry)
Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations 2023
edited by
submission deadline 20 Dec 2024 | 3 articles | Viewed by 4211 | Submission Open
Keywords: rheumatic diseases; pathophysiology; therapy; pulmonary fibrosis; pulmonary arterial hypertension (PAH); imaging techniques
(This special issue belongs to the Section Pharmacology)
Wnt Signaling in Cancer: New Advances
edited by
submission deadline 20 Dec 2024 | Viewed by 75 | Submission Open
Keywords: Wnt signaling; cancer; colorectal cancer; cancer stem cells; stem cells; small molecules; oncogenesis
(This special issue belongs to the Section Pharmacology)
Peptide Drug Conjugates and Their Applications submission deadline 20 Dec 2024 | Viewed by 43 | Submission Open
Keywords: peptides; endogenous opioid peptides; peptidomimetics; neuropeptides; peptide– metal complexes; opioid receptors; chemical biology of peptides
(This special issue belongs to the Section Biopharmaceuticals)
The 20th Anniversary of Pharmaceuticals—Emerging Trends in Biopharmaceuticals submission deadline 22 Dec 2024 | 15 articles | Viewed by 26437 | Submission Open
Keywords: proteins; nucleic acids; aptamers; Glycans; macromolecules; antibodies; phages; viruses; therapeutic tools; peptidomimetics
(This special issue belongs to the Section Biopharmaceuticals)
Design, Synthesis and Biological Evaluation with Potential Anti-inflammatory Activity submission deadline 22 Dec 2024 | 2 articles | Viewed by 3538 | Submission Open
Keywords: anti-inflammatory; COX/LOX; IL-6; JAK; STAT3; p38MAPK; TNF-α ; asthma; Alzheimer's disease; cancer
(This special issue belongs to the Section Medicinal Chemistry)
Past, Present and Future Radiotracer Techniques: Radiopharmaceuticals in Cancer Theranostics submission deadline 22 Dec 2024 | 1 articles | Viewed by 1539 | Submission Open
Keywords: diagnostic radiotracers; therapeutic radiopharmaceuticals; theranostics; radiolabeling techniques; GMP compliance; automated synthesis and quality control; pre-clinical studies; translation into clinics and first-in-human studies; clinical trials; regulatory approval
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Therapeutic Potential of Bee Products
edited by Călin Vasile Andriţoiu, and
submission deadline 22 Dec 2024 | Viewed by 712 | Submission Open
Keywords: Apitherapy; bee products; honey; polen; apilarnil; Royal Jelly; polymer delivery system of apitherapy products
(This special issue belongs to the Section Natural Products)
Pharmacotherapy for Schizophrenia: New Advances
edited by Dennis Kätzel and Holger Rosenbrock
submission deadline 22 Dec 2024 | Viewed by 194 | Submission Open
Keywords: schizophrenia; psychosis; pharmaco-resistance; refractory symptoms; cognitive symptoms; negative symptoms; aberrant salience; drug repurposing; target discovery; drug development; translatable biomarkers; endophenotypes; precision medicine; patient stratification; circuit neuroscience; glutamate hypothesis; dopamine hypothesis; oxidative stress
(This special issue belongs to the Section Pharmacology)
New Platforms for Cancer Treatment—Emerging Advances
edited by Fernanda Karoline Vieira da Silva Torchelsen, Maria Alice de Oliveira, Renata Tupinambá Branquinho and
submission deadline 22 Dec 2024 | Viewed by 77 | Submission Open
Keywords: cancer treatment; emerging advances; nanotechnology; nanotheranostics; novel drugs; nanostructures; pre-clinical studies
(This special issue belongs to the Section Pharmaceutical Technology)
Medicinal Plants: Current Insights into Their Biological Activities and Integration with Micro- or Nanotechnologies submission deadline 22 Dec 2024 | Viewed by 46 | Submission Open
Keywords: medicinal plants; plant extracts; bioactive nanomaterials; inorganic materials; organic materials; drug delivery systems
Topoisomerases as Targets for Novel Drug Discovery
edited by
submission deadline 25 Dec 2024 | 7 articles | Viewed by 18397 | Submission Open
Keywords: topoisomerase; type I topoisomerase; type II topoisomerase; DNA Gyrase; DNA topology; catalytic inhibitors; topo II poisons; DNA gyrase inhibitors; Novel bacterial topoisomerase inhibitors (NBTI); anticancer agents; antibacterial agents
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advancements in the Development of Antiprotozoal Agents
edited by Francesco Saccoliti and Alessandro Giraudo
submission deadline 25 Dec 2024 | 1 articles | Viewed by 1460 | Submission Open
Keywords: antiprotozoal; drug discovery; chemotherapy; parasite; protozoa; mechanism of action of antiprotozoal agents
(This special issue belongs to the Section Medicinal Chemistry)
The Pharmacology of Bisphosphonates: New Advances submission deadline 25 Dec 2024 | Viewed by 125 | Submission Open
Keywords: bisphosphonates; bisphosphonic acids; pharmacology of bisphosphonates; pharmacokinetics; pharmacodynamics; hypocalcemia; osteonecrosis; gastrointestinal disturbances; delivery systems of bisphosphonates; bisphosphonate prodrugs; osteoporosis; breast cancer; prostate cancer; hypercalcemia; antiresorptive properties; antibacterial properties; anti-cancer properties; antiparasitic activity; antiprotozoal properties; antiviral properties; effects of drugs on the metabolism and biomechanical properties of bone tissue; properties and effects of bisphosphonates in in vitro and/or in vivo experimental models of bone disorders; different bisphosphonates in an in vitro experimental model of bone disease
(This special issue belongs to the Section Pharmacology)
Recent Advances in Ocular Pharmacology submission deadline 25 Dec 2024 | Viewed by 63 | Submission Open
Keywords: ophthalmology; ocular diseases; drug delivery; drug targeting; controlled drug release; eye drops; biopolymers; nanomedicine; clinical applications; clinical trials
(This special issue belongs to the Section Pharmacology)
Pharmaceutical Potential of Selenium submission deadline 25 Dec 2024 | Viewed by 62 | Submission Open
Keywords: pleiotropic selenium reagents; drug delivery; disease treatment and prevention; selenium metabolism; selenium toxicity
(This special issue belongs to the Section Pharmacology)
Structural and Computationally Driven Molecule Design in Drug Discovery: 2nd Edition submission deadline 25 Dec 2024 | Viewed by 39 | Submission Open
Keywords: structural dynamics studies; computer-aided drug design; molecular dynamics simulations; molecular docking; virtual screening; QSAR; in silico ADMET; artificial intelligence (AI) techniques
(This special issue belongs to the Section Medicinal Chemistry)
Discovering Novel Drugs from Plants
edited by
submission deadline 25 Dec 2024 | Viewed by 34 | Submission Open
Keywords: natural products; drug discovery; bioactive compound; extraction; ethnopharmacology; preclinical test
(This special issue belongs to the Section Natural Products)
In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research, 2nd Edition submission deadline 30 Dec 2024 | 6 articles | Viewed by 9605 | Submission Open
Keywords: nuclear molecular imaging; drug development; in vivo application; biomarkers; nuclear precision medicine
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Computational Predictions of Molecules with Potential Therapeutic Effects
edited by
submission deadline 30 Dec 2024 | Viewed by 31 | Submission Open
Keywords: biophysics; medicinal chemistry; drug discovery; molecular docking; molecular dynamics; structure-activity relationships; computer-aided drug design (CADD)
(This special issue belongs to the Section Medicinal Chemistry)
The 20th Anniversary of Pharmaceuticals—Advances in Natural Products submission deadline 31 Dec 2024 | 4 articles | Viewed by 4587 | Submission Open
(This special issue belongs to the Section Natural Products)
Recent Advances in Psychiatric Medications
edited by and Paweł Zagożdżon
submission deadline 31 Dec 2024 | Viewed by 340 | Submission Open
Keywords: mental health treatment; psychopharmacology; antidepressants; antipsychotics; side effects; safety profiles; treatment resistance; adherence issues
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products in Drug Discovery in the 21st Century: Challenges and Opportunities
edited by
submission deadline 31 Dec 2024 | Viewed by 285 | Submission Open
Keywords: natural products; bioactive natural compounds; marine drugs; medicinal plants; in vitro and in vivo biological activity; pharmacological activity; drug discovery; medicinal and technological applications; medicinal chemistry
(This special issue belongs to the Section Natural Products)
Biomarkers and Therapeutic Targets for Melanoma
edited by
submission deadline 31 Dec 2024 | Viewed by 143 | Submission Open
Keywords: melanoma; tumor microenvironment; tumor metabolism; omics technologies; precision medicine; biomarkers; melanoma treatment approaches; drug resistance
(This special issue belongs to the Section Pharmacology)
Natural Compounds as Potential Anticancer, Anti-inflammatory and Antioxidant Agents in Medicine submission deadline 31 Dec 2024 | Viewed by 133 | Submission Open
Keywords: phytochemistry of plant extracts; plant secondary metabolites; clinical applications; in vitro; in vivo; ex vivo studies; cell and tissue cultures
(This special issue belongs to the Section Natural Products)
Therapeutic Potential of Aldehyde Dehydrogenases submission deadline 31 Dec 2024 | Viewed by 97 | Submission Open
Keywords: ALDH; cancer; cancer stem cells; diabetes; Parkinson’ s disease; Alzheimer’ s disease; ALDH inhibitors; ALDH signaling; CSC-based therapeutics; therapeutic strategies
(This special issue belongs to the Section Medicinal Chemistry)
Current Pharmacotherapy for Viral Hepatitis
edited by
submission deadline 31 Dec 2024 | Viewed by 64 | Submission Open
Keywords: liver; viral hepatitis; HBV; HCV; HDV; therapy
(This special issue belongs to the Section Pharmacology)
Discovery and Development of Novel Analgesics
edited by Ethel Antunes Wilhelm and Angélica Schiavom dos Reis
submission deadline 31 Dec 2024 | Viewed by 45 | Submission Open
Keywords: analgesics; pain management; pain biology; pharmacological potential; preclinical models; therapeutic development; synthetic compounds; natural compounds; neuropathic pain; chemotherapy-induced neuropathy
(This special issue belongs to the Section Medicinal Chemistry)
Glycomimetics and Glycoconjugates in Drug Discovery, 2nd Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 29 | Submission Open
Keywords: glycoconjugates; glycomimetics; carbohydrate– protein interactions; carbohydrate-acting enzymes; medicinal glycochemistry; drug design; drug discovery
(This special issue belongs to the Section Biopharmaceuticals)
Computational Methods in Drug Development
edited by
submission deadline 31 Dec 2024 | Viewed by 17 | Submission Open
Keywords: computational modeling; DNA/RNA and protein; drug discovery and design; systems biology; channels and membranes; biomedical data analysis; artificial intelligence; molecule docking and scoring
(This special issue belongs to the Section Medicinal Chemistry)
Pharmaceutical Application of Essential Oils
edited by
submission deadline 12 Jan 2025 | Viewed by 25 | Submission Open
Keywords: essential oils; bacteria; fungi; alternative therapy; antimicrobial resistance; mechanism of action
(This special issue belongs to the Section Natural Products)
Therapeutic Potential of Chalcone Derivatives
edited by Hélcio Silva Dos Santos
submission deadline 15 Jan 2025 | Viewed by 61 | Submission Open
Keywords: chalcones; pharmacological potential; structural characterization; bioactivity; in silico study; cytotoxicity; quantum chemical calculations; ecapsulation
(This special issue belongs to the Section Pharmacology)
Biological and Pharmacological Research on Indole-3-Carbinol (I3C) and Its Derivatives submission deadline 15 Jan 2025 | Viewed by 31 | Submission Open
Keywords: indole-3-carbinol; natural and synthetic derivatives of I3C; synthetic procedures; biosynthetic processes; in vitro; in vivo and clinical studies; mechanism of action; biological properties; pharmacological properties; potential therapeutic applications in health and disease
(This special issue belongs to the Section Pharmacology)
Exploring the Anticancer and Immunomodulatory Mechanisms of Phytochemicals and Natural Bioactive Compounds
edited by Suyun Lyu
submission deadline 15 Jan 2025 | Viewed by 8 | Submission Open
Keywords: natural products; phytochemicals; anticancer; immunomodulation; bioactive compounds
(This special issue belongs to the Section Pharmacology)
Chemoinformatics and Drug Design, 2nd Edition
edited by Weifan Zheng
submission deadline 20 Jan 2025 | Viewed by 8 | Submission Open
Keywords: artificial intelligence (AI); machine learning (ML); representation learning; cheminformatics; drug discovery; drug repurposing; biological activity prediction; drug– target– disease interactions
(This special issue belongs to the Section Medicinal Chemistry)
Advanced Strategies in Drug Design and Development of Small Molecules as Therapeutic Agents
edited by
submission deadline 25 Jan 2025 | 5 articles | Viewed by 4968 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Sirtuins as Novel Biological Targets for Pharmacological Intervention in Physiology and Pathology submission deadline 25 Jan 2025 | 1 articles | Viewed by 1435 | Submission Open
Keywords: sirtuins; metabolism; cancer; hypoxia; damage recovery; cell death
(This special issue belongs to the Section Pharmacology)
Novel Anti-proliferative Agents, 2nd Edition
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 2566 | Submission Open
Keywords: medicinal chemistry; drug discovery; natural compounds; synthetic compounds; organic synthesis; bioactivity; anticancer drugs; antiproliferative activity
(This special issue belongs to the Section Medicinal Chemistry)
Hsp90 Inhibitors: Progress, Challenges, and Opportunities in Drug Discovery and Development submission deadline 31 Jan 2025 | Viewed by 92 | Submission Open
Keywords: Hsp90; drug discovery; synthesis; chaperone; therapeutic potential; cancer treatment; neurodegenerative diseases; infection resistance mechanisms; research advancements; therapeutic development
(This special issue belongs to the Section Medicinal Chemistry)
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