Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Small-Molecule Inhibitors for Novel Therapeutics
edited by and Simone Giovannuzzi
submission deadline 31 Jan 2025 | Viewed by 189 | Submission Open
Keywords: small molecules; enzyme inhibition/activation; protein modulation; novel therapeutics; high-throughput screening; target proteins; drug delivery
Innovative Approaches to Radiopharmaceuticals: Advances in Design, Labeling, and Applications
edited by Shvan J. Raheem and
submission deadline 31 Jan 2025 | Viewed by 152 | Submission Open
Keywords: radiochemistry; radiopharmaceutical; radiotracers
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Molecular Mechanisms and Treatment of Brain Cancer: Recent Advances and Future Trends
edited by
submission deadline 31 Jan 2025 | Viewed by 148 | Submission Open
Keywords: brain cancer; molecular mechanism; treatment; diagnosis; in vitro; in vivo; models
(This special issue belongs to the Section Pharmacology)
Therapeutic Targets and Therapies for the Treatment of Oral Cancer and Oral Diseases submission deadline 31 Jan 2025 | Viewed by 113 | Submission Open
Keywords: oral cancer; oral and maxillofacial surgery; oral and maxillofacial pathology medicine; periodontics and oral pathology; immunohistochemistry
(This special issue belongs to the Section Pharmacology)
Bone Disorder Therapeutics: Novel Drug Candidates and Treatment Strategies
edited by
submission deadline 31 Jan 2025 | Viewed by 110 | Submission Open
Keywords: bone health; osteoporosis; arthritis; osteoarthritis; bone cancer; regeneration; repair; metabolism; gene therapy; cell therapy
(This special issue belongs to the Section Pharmacology)
Natural Products-Assisted Organic Synthesis in Medicinal Chemistry submission deadline 31 Jan 2025 | Viewed by 109 | Submission Open
Keywords: total organic synthesis; preparative methods of natural products; natural carboxylic acids; derivatives of organic carboxylic acids; amino acids; carbonyl derivatives; phenolic compounds; heterocyclic compounds; antioxidant activity; antifungal activity; antimicrobial activity; anti-inflammatory activity; cytotoxicity; anti-cancer activity; ROS activity; DNA damages; structure-activity studies; DFT calculations for synthetic organic products; molecular docking
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Modulating Mitophagy with Novel Drugs/Compounds
edited by
submission deadline 5 Feb 2025 | Viewed by 84 | Submission Open
Keywords: heart disease; mitochondria; mitophagy; mitochondrial quality control; drug screening
(This special issue belongs to the Section Pharmacology)
New Street Opioids, Their Mixtures and Emerging Interventions
edited by Michael V. Voronkov
submission deadline 10 Feb 2025 | Viewed by 175 | Submission Open
Keywords: fentanyl; naloxone; xylazine; nitazenes; opioid overdose; addiction; polypharmacology; polypharmacy; animal models
(This special issue belongs to the Section Pharmacology)
Selective Histone Deacetylase Isoforms as Potential Therapeutic Targets
edited by
submission deadline 15 Feb 2025 | 4 articles | Viewed by 5768 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Applications of Beehive Products for Wound Repair and Skin Care
edited by Simona Martinotti
submission deadline 15 Feb 2025 | Viewed by 146 | Submission Open
Keywords: anti-aging; antibacterial properties; healing properties; honey; propolis; bee venom; wound repair; skin care
(This special issue belongs to the Section Natural Products)
Natural Products in Health Promotion and Disease Prevention 2024 submission deadline 20 Feb 2025 | 4 articles | Viewed by 3489 | Submission Open
Keywords: natural products; nutraceuticals; bioactive compounds; traditional medicine; drug discovery
(This special issue belongs to the Section Natural Products)
Targeted Therapies for Epilepsy
edited by , and Chiara Lucchi
submission deadline 20 Feb 2025 | 2 articles | Viewed by 2606 | Submission Open
Keywords: epilepsy; temporal lobe epilepsy; neurological disorder; spontaneous recurrent seizures; epileptogenesis; antiepileptogenic medications; antiseizure medications; drug-resistant epilepsy; adverse effects; drug discontinuation
(This special issue belongs to the Section Pharmacology)
Nano-Strategies in Fighting Cancer
edited by Ahmad Sohrabi Kashani and
submission deadline 20 Feb 2025 | 1 articles | Viewed by 2403 | Submission Open
Keywords: nanomedicines; targeted therapy; intracellular diagnosis; cell mechanics; nano-biosensor; nano-bio interaction; mechanobiology; nano-biomechanics; drug delivery; migration
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Inhalation Therapy
edited by and
submission deadline 20 Feb 2025 | 1 articles | Viewed by 1896 | Submission Open
Keywords: inhalation therapy; pulmonary delivery; aerosols; dry powder inhalation; inhalable micro and nanoparticles; pulmonary deposition
(This special issue belongs to the Section Pharmaceutical Technology)
Novel Therapeutics in Hematology
edited by
submission deadline 20 Feb 2025 | 1 articles | Viewed by 496 | Submission Open
Keywords: hematopoietic cell transplantation; cell therapy; acute myeloid leukemia; graft-versus-host disease; hematologic malignancies
(This special issue belongs to the Section Pharmacology)
New Pharmaceuticals in Diagnosis, Prognosis and Treatment of Myelofibrosis and Myeloproliferative Neoplasms
edited by and Calogero Vetro
submission deadline 20 Feb 2025 | Viewed by 115 | Submission Open
Keywords: philadelphia-negative Myeloproliferative neoplasms; JAK2; CALR; MPL; thrombotic risk; new targeted therapies; future landscape in MPN; inhibitors
(This special issue belongs to the Section Medicinal Chemistry)
Tumor Immunopharmacology submission deadline 21 Feb 2025 | Viewed by 363 | Submission Open
Keywords: immunotherapy; immunomodulation; drug development; cytokine receptor antagonist; T-cell based therapies; therapeutic antibodies; drug delivery; cancer vaccine
(This special issue belongs to the Section Pharmacology)
Indole Derivatives as Targeted Melatonin and Serotonin Receptor Ligands submission deadline 23 Feb 2025 | Viewed by 94 | Submission Open
Keywords: melatonin receptors; serotonin receptors; medicinal chemistry; natural products; drug design; antioxidant activity; multi-target compounds
(This special issue belongs to the Section Medicinal Chemistry)
Drug Discovery and Development Targeting NMDA Receptors
edited by
submission deadline 24 Feb 2025 | 1 articles | Viewed by 3013 | Submission Open
Keywords: glutamate; NMDAR antagonist; CNS drug discovery; Depression; neuropathic pain; Ketamine; memory and learning; ionotropic receptors
(This special issue belongs to the Section Medicinal Chemistry)
Development of Novel Radiopharmaceuticals for SPECT and PET Imaging
edited by
submission deadline 24 Feb 2025 | Viewed by 77 | Submission Open
Keywords: oncology; theranostics; inflammation/infection diagnosis; autoimmune diseases; neurodegenerative diseases; cardiovascular diseases
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Bioactive Substances, Oxidative Stress, and Inflammation submission deadline 25 Feb 2025 | 7 articles | Viewed by 17011 | Submission Open
Keywords: bioactive compounds; oxidative stress; chronic inflammation; chronic non-communicable diseases; polyphenol; vitamins; omega-3 fatty acids
(This special issue belongs to the Section Natural Products)
Therapeutic Potential of Natural Products in Internal Diseases
edited by and
submission deadline 25 Feb 2025 | 8 articles | Viewed by 12885 | Submission Open
Keywords: medicinal plants; phytotherapy; herbal treatment; natural products; herbalism; traditional medicine; cardiovascular disease; lung disease; liver disease; gastrointestinal disease; kidney disease; obesity; diabetes; rheumatological disease
(This special issue belongs to the Section Natural Products)
Therapeutic Potential for Cannabinoid and Its Receptor submission deadline 25 Feb 2025 | 7 articles | Viewed by 9843 | Submission Open
Keywords: endocannabinoid system; cannabinoid receptor ligands; medical marihuana; cannabinoid-based therapies
(This special issue belongs to the Section Pharmacology)
The Mode of Action of Herbal Medicines and Natural Products
edited by Hongnan Cao
submission deadline 25 Feb 2025 | 6 articles | Viewed by 9357 | Submission Open
(This special issue belongs to the Section Natural Products)
Natural Products and Their Modifications as Agents Used in the Fight against Pathogens
edited by
submission deadline 25 Feb 2025 | 6 articles | Viewed by 9302 | Submission Open
Keywords: plant extract; natural compounds; multidrug-resistant strains; intestinal microbiota; chemical modyfication; biotransformation
(This special issue belongs to the Section Natural Products)
Gut Microbiota Metabolites in Intestinal Inflammation and Fibrosis submission deadline 25 Feb 2025 | 4 articles | Viewed by 8399 | Submission Open
Keywords: intestinal inflammation; inflammatory bowel diseases; microbiota; microbiome; probiotics; fecal transplantation
(This special issue belongs to the Section Pharmacology)
Neuroprotective Potential of Natural Products: A Shield against Brain Decay submission deadline 25 Feb 2025 | 4 articles | Viewed by 8017 | Submission Open
Keywords: neuroprotection; natural products; extract; oxidative stress; degenerative diseases; adjuvant therapies
(This special issue belongs to the Section Natural Products)
Bioactive Compounds Derived from Plants and Their Medicinal Potential submission deadline 25 Feb 2025 | 9 articles | Viewed by 7166 | Submission Open
Keywords: phytopharmaceutical drugs; activity screening (antimicrobial; antioxidant; anticancer; and immunomodulatory activity); experimental models (in vitro; ex vivo; in vivo; etc.); microfluidic systems
(This special issue belongs to the Section Natural Products)
Small Molecules in Targeted Cancer Therapy and Diagnosis
edited by
submission deadline 25 Feb 2025 | 4 articles | Viewed by 6626 | Submission Open
Keywords: small molecules; cancer therapy; cancer diagnosis; targeted therapy; theranostic agents
(This special issue belongs to the Section Pharmacology)
Pharmacological Therapies for Stress-Related Disorders and Autism Spectrum Disorder
edited by and
submission deadline 25 Feb 2025 | 3 articles | Viewed by 6452 | Submission Open
Keywords: new targets and therapies for stress-related disorders; molecular mechanism of drugs; ASD; PTSD; MDD; antidepressant; depression; animal model for depression; ASD; microbiome; gut-brain axis; brain electrophysiology; neuron activity in ASD
(This special issue belongs to the Section Pharmacology)
Drug and Gene Delivery Strategies for Breast Cancer Therapy
edited by
submission deadline 25 Feb 2025 | 3 articles | Viewed by 6027 | Submission Open
Keywords: drug delivery system; gene delivery; breast cancer; nanoparticles; RNAi; gene therapy; liposomes; micelles
(This special issue belongs to the Section Pharmaceutical Technology)
The Medical Applications of Novel PET Radiopharmaceuticals
edited by and Florent L. Besson
submission deadline 25 Feb 2025 | 4 articles | Viewed by 4904 | Submission Open
Keywords: nuclear medicine; radiotracers; radiopharmaceuticals; positron emission tomography; diagnostics; medical applications
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Psychiatric Drug Treatment and Drug Addiction submission deadline 25 Feb 2025 | 2 articles | Viewed by 3615 | Submission Open
Keywords: drug addiction; drug abuse; psychiatric disorder; drug dependence
(This special issue belongs to the Section Pharmacology)
Advances in Pediatric Drug Formulations submission deadline 25 Feb 2025 | 1 articles | Viewed by 1322 | Submission Open
Keywords: pediatric dosage forms; child-friendly dosage forms; age-appropriate dosage forms; acceptability; administration devices; taste-masking; compounded pediatric formulations
(This special issue belongs to the Section Pharmaceutical Technology)
Small Molecule Drug Discovery: Driven by In-Silico Techniques
edited by
submission deadline 25 Feb 2025 | 1 articles | Viewed by 1282 | Submission Open
Keywords: drug discovery; nutraceuticals; virtual screening; docking; molecular dynamics; pharmacophore; lead compound
(This special issue belongs to the Section Medicinal Chemistry)
Radiopharmaceuticals and Nanotechnology
edited by and Céline Mirjolet
submission deadline 25 Feb 2025 | 1 articles | Viewed by 1257 | Submission Open
Keywords: radiopharmaceutics; nanoparticle; radiation (external beam radiotherapy; nuclear medicine; brachytherapy; PET; SPECT; … ); theranostic; nanomedicine
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Advances in Nuclear Medicine submission deadline 25 Feb 2025 | Viewed by 219 | Submission Open
Keywords: radiopharmaceuticals; PET; SPECT; hybrid imaging modalities; radionuclide therapies; radiotracers; imaging techniques
Flavonoids in Medicinal Chemistry: Trends and Future Directions
edited by
submission deadline 25 Feb 2025 | Viewed by 202 | Submission Open
Keywords: flavonoids; synthesis; natural products; medicinal chemistry; biological activity
(This special issue belongs to the Section Medicinal Chemistry)
Neuropsychiatric Disorders: Pharmacological Aspects submission deadline 25 Feb 2025 | Viewed by 64 | Submission Open
Keywords: neuropsychiatric disorders; DSM-V; pharmacodynamics; innovative therapies; animal models; neuropsychiatric patients; trauma and stress; neurodegeneration; affective disorders; neurodevelopmental disorders; schizophrenia; sleep disorders; comorbidities; cardiovascular; coagulopathies; gastrointestinal; microbiome– gut– brain axis
(This special issue belongs to the Section Pharmacology)
Recent Advancements in Radiochemistry and PET Radiotracer Development: 2nd Edition
edited by Kenneth Dahl and
submission deadline 25 Feb 2025 | Viewed by 36 | Submission Open
Keywords: radiochemistry; labeling; automation; GMP; PET; radiotracer; radioligand; radiopharmaceutical; drug discovery
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Prospects for the Application of Antibiotics in Drug Delivery Systems: New Advances
edited by Magdalena Grazul
submission deadline 25 Feb 2025 | Viewed by 22 | Submission Open
Keywords: antibiotics; drug delivery system; antimicrobial agents; multidrug resistance; novel approaches; drug discovery and development
(This special issue belongs to the Section Pharmaceutical Technology)
Pharmacotherapy for Macular Diseases 2024
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1545 | Submission Open
Keywords: clinical ophthalmology; macular degeneration; retinal diseases
(This special issue belongs to the Section Pharmacology)
Antioxidant and Anti-inflammatory Effects of Natural Product Extracts
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 537 | Submission Open
Keywords: inflammation; oxidative stress; natural products; antioxidant properties; anti-inflammatory properties; omic technologies
(This special issue belongs to the Section Natural Products)
Drug Resistance Against Cancer Treatment submission deadline 28 Feb 2025 | Viewed by 237 | Submission Open
Keywords: multidrug resistance (MDR); chemotherapy; P-glycoprotein (P-gp); ATP-binding cassette (ABC) transporters; molecularly targeted drugs; inherent resistance; acquired resistance; signaling pathways
(This special issue belongs to the Section Pharmacology)
Progress of Hydrogel Applications in Novel Drug Delivery Platforms submission deadline 28 Feb 2025 | Viewed by 199 | Submission Open
Keywords: hydrogels; targeted drug delivery; drug release; drug delivery; smart hydrogels; stimuli-responsive hydrogels; controlled release; hydrogel-based drug delivery; drug carriers
(This special issue belongs to the Section Pharmaceutical Technology)
Advancements in the Study of Biological Activities of Plant Extracts and Components submission deadline 28 Feb 2025 | Viewed by 151 | Submission Open
Keywords: natural products; enzyme kinetics; antioxidants; bioactive compounds; bioactive plant extracts
(This special issue belongs to the Section Natural Products)
Antibiotic Resistance in Gram-Negative Bacteria: The Threat From the Pink Corner, 2nd Edition submission deadline 28 Feb 2025 | Viewed by 91 | Submission Open
Keywords: gram-negative; pseudomonas; acinetobacter; campylobacter; helicobacter; klebsiella; enterobacteriaceae; arcobacter; phages; complementary alternative medicine; antimicrobial peptides; food security; hospital acquired infections; microbiome; gram negative pathogens; antibiotic resistance; virulence and other molecular mechanisms
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Drug Metabolism, Transport, and Pharmacokinetics
edited by Agnieszka Bienert and
submission deadline 28 Feb 2025 | Viewed by 88 | Submission Open
Keywords: pharmacokinetic analysis; analytical methods suitable for pharmacokinetics studies; pharmacogenetics in drug pharmacokinetics; clinical pharmacokinetics; drug concentrations in plasma and tissue; population PK modeling; drug metabolic pathways; drug transport across barriers
(This special issue belongs to the Section Pharmacology)
Recent Advances in Androgen Receptor Modulators
edited by Hong-Yo Kang
submission deadline 28 Feb 2025 | Viewed by 75 | Submission Open
Keywords: androgens; androgen receptor; SARMs; ARDs; prostate cancer; muscle wasting; hypogonadism; selective modulation; pharmacokinetics; tissue specificity; combination therapy; drug resistance; bioavailability; targeted therapy
(This special issue belongs to the Section Pharmacology)
Novel Therapeutic Approaches for Chronic Urticaria: Advances and Challenges
edited by Luis Felipe Ensina
submission deadline 28 Feb 2025 | Viewed by 28 | Submission Open
Keywords: chronic urticaria; current management; biosimilar pharmaceuticals; biologic drugs; monoclonal antibodies; tyrosine kinase inhibitors
(This special issue belongs to the Section Pharmacology)
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