Recent Advances in Hepatic-Targeted Drug Delivery Systems

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 367

Special Issue Editors


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Guest Editor
“Aurel Ardelean” Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania
Interests: regenerative medicine; phytotherapy; liver fibrosis; drug delivery systems
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Guest Editor
Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 Timișoara, Romania
Interests: molecular signaling; inflammation pathways; phytotherapy; liver fibrosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue titled “Recent Advances in Hepatic-Targeted Drug Delivery Systems”. The liver, as the largest visceral organ in the human body, plays a variety of crucial roles in processes including metabolism, detoxification, protein synthesis, and bile secretion. Consequently, the treatment of liver diseases has always been a focal point in medical research. Hepatic-targeted drug delivery systems leverage the physiological characteristics of the liver to innovatively deliver therapeutic agents directly to the liver, thereby enhancing efficacy and minimizing side effects on other organs.

In this Special Issue of Pharmaceutics, we invite authors to submit original research articles or reviews in the fields of hepatic chronic diseases. Research areas may include (but are not limited to) the following topics:

  • Nano Drug Delivery Systems: Exploring the applications of nanoparticles for enhancing liver targeting, improving drug stability, and controlling drug release;
  • Phytotherapies: Investigating how active components from plants can enhance their pharmacological effects through hepatic-targeted delivery systems;
  • Gene Delivery Systems: Analyzing the applications of gene therapy in liver diseases and how hepatic targeting techniques can improve the efficiency and safety of gene delivery;
  • Personalized Medicine: Discussing how individual differences can be utilized to customize drug delivery strategies for optimal treatment outcomes in liver therapy;
  • Potential of Combination Therapies: Exploring the combination of different drugs and treatment methods, as well as their synergistic effects, in hepatic-targeted delivery.

We look forward to receiving your contributions.

Dr. Cornel Baltă
Dr. Oana-Maria Boldura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hepatic drug delivery
  • phytotherapy
  • nanomedicine
  • lipid complexes
  • targeted therapies
  • liver diseases
  • drug vehicles
  • biomaterials
  • hepatocellular carcinoma
  • liposome
  • polymeric nanoparticles
  • lipid nanoparticles
  • hepatic stellate cell

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Published Papers

This special issue is now open for submission.
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