Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 10 articles | Viewed by 23777 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro– in vivo correlations; physiologically-based biopharmaceutical models; physiologically-based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing
edited by Carolina Martinez and María Jimena Prieto
submission deadline 30 Nov 2025 | 11 articles | Viewed by 18851 | Submission Open
Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements and Innovations in Antibody Drug Conjugates
edited by , Shivaji Edupuganti and Ebaston Thankarajan
submission deadline 30 Nov 2025 | 5 articles | Viewed by 8915 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Inorganic Nanomaterials for the Development of Drug Delivery and Biomedical Applications
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 8679 | Submission Open
Keywords: inorganic nanoparticles; drug delivery; disease diagnosis; disease treatment; nano-biosensor; cancer theranostics; cancer imaging
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hybrid Nanoparticles for Cancer Therapy
edited by Jacy Gameiro
submission deadline 30 Nov 2025 | 5 articles | Viewed by 7546 | Submission Open
Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Naturally Derived Materials-Based Drug Delivery Systems and Their Biomedical Applications
edited by and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 6932 | Submission Open
Keywords: naturally derived material; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Granulation Processes in Pharmaceutical Formulation Systems
edited by Krunoslav Žižek and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5544 | Submission Open
Keywords: granulation; drug formulation; tableting; process modelling; process optimization; scale-up
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Microneedles for Drug and Vaccine Delivery
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4265 | Submission Open
Keywords: physical enhancement technologies; fabrication; characterization; applications; drug delivery; cosmetic applications; diagnostic; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Brain Tumors Treatment: Current and Future Challenges from Drug Formulations to Delivery Methods
edited by , Sara Badodi and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3503 | Submission Open
Keywords: blood– brain barrier pathophysiology in different tumors; pediatric brain tumors; adult brain tumors; considerations for adult vs. pediatric drug delivery development; nanocarriers and nanoparticles; focused ultrasound; convection enhanced delivery; intranasal delivery; intra-arterial delivery; combination strategies
(This special issue belongs to the Section Drug Targeting and Design)
Natural Compounds in Drug Delivery Systems submission deadline 30 Nov 2025 | 2 articles | Viewed by 3232 | Submission Open
Keywords: natural products; extraction techniques; phytochemical analyses; natural compounds; biological active compounds; new formulations; encapsulated technics; biotechnology; drug delivery systems; bioavailability; pharmacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 30 Nov 2025 | 2 articles | Viewed by 2929 | Submission Open
Keywords: solid dosage forms (tablets; capsules; pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
In Vitro and In Vivo Biopharmaceutics Assessment of Silica-Based Drug Delivery Systems: Characterization, Drug Release, and Biological Performance submission deadline 30 Nov 2025 | 2 articles | Viewed by 2734 | Submission Open
Keywords: drug delivery systems; mesoporous silica nanoparticles; biopharmaceutics evaluation; controlled drug release; drug release kinetics; in vivo performance; in vitro methodologies; pharmaceutical nanotechnology; stimuli-responsive systems; therapeutic efficacy
(This special issue belongs to the Section Biopharmaceutics)
Controlled Delivery of Cosmeceuticals Using Nanotechnology submission deadline 30 Nov 2025 | 1 articles | Viewed by 2618 | Submission Open
Keywords: cosmeceuticals; skin; targeting; cosmetics; nanotechnology; delivery; formulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanosystems for Advanced Diagnostics and Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 2207 | Submission Open
Keywords: nanosystems; theranostics; nanomedicine; molecular imaging; targeted drug delivery; radiolabeled nanoparticles; image guided therapy; smart nanocarriers; nanoradiopharmaceuticals; nanotechnology in diagnostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanoemulsions for Nose-to-Brain Drug Delivery
edited by Clóvis Orlando Pereira Da Fonseca and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2154 | Submission Open
Keywords: nanoemulsion; intranasal; pharmacokinetics; nose-to-brain; neurology; olfactory; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
In Silico Approaches of Drug–Target Interactions
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2043 | Submission Open
Keywords: in silico drug discovery; drug– target interactions; virtual screening; molecular modeling; machine learning in drug design; ADME predictions
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Vaccine Delivery and Vaccine Administration submission deadline 30 Nov 2025 | 1 articles | Viewed by 2040 | Submission Open
Keywords: vaccine delivery; vaccination; vaccine immunity; humoral immune response; cell-mediated immunity; infectious diseases; vaccine administration; novel routes of vaccination; nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Therapeutic Agents and Innovative Delivery Systems Against Infectious Diseases
edited by Sara Consalvi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1990 | Submission Open
Keywords: medicinal chemistry; antibacterials; antivirals; antimicrobials; drug resistance; drug delivery; drug candidate; drug repurposing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Therapeutic Drug Monitoring as a Useful Tool in Therapy Improvement, 3rd Edition submission deadline 30 Nov 2025 | 2 articles | Viewed by 1822 | Submission Open
Keywords: drug– drug interactions; pharmacokinetics; therapeutic drug monitoring; machine learning
(This special issue belongs to the Section Clinical Pharmaceutics)
Alternative Animal Models for Nanoparticle-Based Drug Delivery: Efficacy and Toxicity Assessment submission deadline 30 Nov 2025 | 1 articles | Viewed by 1790 | Submission Open
Keywords: alternative animal models; nanoparticle drug delivery; nanomedicine; toxicity assessment; bioavailability; in vivo models; biodistribution studies; therapeutic efficacy; pharmaceutical testing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Drug Delivery Systems: From Nanotechnology to Smart Devices
edited by Mahdi Ghavami and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1711 | Submission Open
Keywords: smart nanoparticles; innovative drug delivery; ingestible devices; targeted delivery systems; controlled release; microfabrication techniques; nano and microtechnology; biocompatible materials; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Innovations in Advanced Drug Delivery Systems: Overcoming Challenges for Personalized Medicine
edited by Hélcio Silva Dos Santos
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1440 | Submission Open
Keywords: drug administration; polymers; structural characterization; nanoparticles; in silico studies; toxicity; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Drug Delivery Systems for Natural Products submission deadline 30 Nov 2025 | 1 articles | Viewed by 1382 | Submission Open
Keywords: natural products; advanced drug delivery systems; liposomes; niosomes; phytosomes; lipid nanoparticles; smart polymers; biodegradable nanoparticles; polymeric nanoparticles; drug carriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Physiologically Based Biopharmaceutics Modeling
edited by Atsushi Kambayashi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1053 | Submission Open
Keywords: oral drug absorption; bioavailability; bioequivalence; modeling and simulation; physiologically based biopharmaceutics modeling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Engineering and Characterisation of Novel Nanomedicine Formulations, 3rd Edition
edited by and Raquel Fernández García
submission deadline 30 Nov 2025 | 1 articles | Viewed by 716 | Submission Open
Keywords: nanoparticles; liposomes; solid lipid nanocapsules; drug targeting; cancer; infectious diseases; nanovaccines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Carbon-Based Nanomaterials for Pharmaceutical Applications
edited by and Ivana Borišev
submission deadline 30 Nov 2025 | Viewed by 650 | Submission Open
Keywords: carbon-based nanomaterials; drug delivery; fullerenes; graphene; carbon nanotubes; nanodiamonds; carbon dots; biocompatibility; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Anti-Inflammatory Effects from Natural Bioactive Compounds—from Bench to Bedside, 3rd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 559 | Submission Open
Keywords: inflammation; bioproducts; isolated compounds; cytokines; macrophages; autoimmune diseases; in vivo assay; in vitro assay
(This special issue belongs to the Section Drug Targeting and Design)
Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
edited by and Daniel De Vos
submission deadline 30 Nov 2025 | Viewed by 451 | Submission Open
Keywords: phage vector; drug delivery; phage therapy; phage technology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Smart Drug Delivery Systems for Immunotherapeutic Agents submission deadline 30 Nov 2025 | Viewed by 376 | Submission Open
Keywords: immunotherapy; drug delivery systems; nanomedicine; targeted therapy; cancer immunotherapy; lipid nanoparticles; biomaterials; controlled rel ease; immunoengineering; translational medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Metal Nanoparticles in Therapeutics: Pioneering Drug Delivery Systems and Tissue Engineering submission deadline 30 Nov 2025 | Viewed by 290 | Submission Open
Keywords: metal nanoparticles; drug delivery systems; tissue engineering; cancer therapy; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancing Block Co-Polymer Nanomedicines: Innovations in Effective Drug Delivery submission deadline 30 Nov 2025 | Viewed by 276 | Submission Open
Keywords: pluronic-based nanomedicines and hydrogels; gene delivery; advanced drug delivery systems; radiotherapy and photodynamic therapy; combination therapy; polymeric nanomedicines; immunotherapy; nanogels; small-molecule delivery systems; block co-polymers nanomedicines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
A New Generation of Metal Anticancer Drugs
edited by
submission deadline 30 Nov 2025 | Viewed by 244 | Submission Open
Keywords: metal-based drugs; cytotoxicity; cancer; nanoparticles; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Formulation of Lipid-Based Nanocapsules: Drug Release, Permeability, Biocompatibility, and Stability Studies
edited by and Carolina Arrúa
submission deadline 30 Nov 2025 | Viewed by 215 | Submission Open
Keywords: drug delivery; lipid nanocapsules; permeability; biocompatibility; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biocompatible Polymer-Based Nanocarriers and Nanocomposites as Drug Delivery Systems
edited by
submission deadline 30 Nov 2025 | Viewed by 213 | Submission Open
Keywords: biocompatible nanocomposites; polymer-based nanocomposites; drug delivery; controlled-release systems; nanocarriers; nanomedicine; nanocomposite toxicity; vaccines; gene delivery; cancer therapy; neurodegenerative diseases
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Next-Generation Non-Viral Vectors for Gene Therapy and DNA Vaccination
edited by
submission deadline 30 Nov 2025 | Viewed by 213 | Submission Open
Keywords: non-viral vectors; gene therapy; DNA vectors; plasmid vectors; mRNA vectors; lipid nanoparticles (LNPs); cell-free DNA synthesis; gene electrotransfer; targeted gene delivery; non-viral vector manufacturing; clinical translation of gene therapies
(This special issue belongs to the Section Gene and Cell Therapy)
The Preparation of an Exosome/Liposomal Nano-Drug Delivery System and Its Application in the Treatment of Inflammatory Bowel Disease
edited by and
submission deadline 30 Nov 2025 | Viewed by 177 | Submission Open
Keywords: exosomes; liposomes; nano-drug delivery systems; inflammatory bowel disease (IBD); targeted therapy; mucosal drug delivery; drug encapsulation; immunomodulation; nanomedicine; extracellular vesicles; personalized medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
The Exciting Opportunities That Radiopharmaceuticals Have to Offer: Nuclear Medicine Imaging, Therapy and Drug Delivery Systems
edited by Yanli Wang and
submission deadline 30 Nov 2025 | Viewed by 169 | Submission Open
Keywords: PET imaging; theranostics; molecular imaging probes; radionuclide therapy; neuroimaging; radiochemistry
(This special issue belongs to the Section Drug Targeting and Design)
Model-Based Formulation Strategies for Controlled Release of Active Ingredients
edited by , Patrick D. Sinko and
submission deadline 30 Nov 2025 | Viewed by 166 | Submission Open
Keywords: in vitro and in vivo correlation; simultaneous dissolution– absorption evaluation; controlled release; sustained release; drug delivery systems; nanoparticles; micelles; liposomes; nanomaterials; amorphous solid dispersions; molecular dynamics simulations; computational fluid dynamics; computationally designed proteins; computationally designed peptides; pharmacokinetic model; pharmacometric model; 3D printing (personalized medicines/materials development/printing technologies)
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Smart Radiotherapy Biomaterials for Cancer Therapy and Imaging submission deadline 10 Dec 2025 | 1 articles | Viewed by 1294 | Submission Open
Keywords: multifunctional biomaterials; theranostic biomaterials; smart drug delivery systems; nanobiomaterials; cancer radiotherapy; polymer-based biomaterials nanocarriers customizable biomaterials for cancer therapy and imaging smart nanomaterials
(This special issue belongs to the Section Drug Targeting and Design)
PLGA Implants for Controlled Drug Release
edited by Emma Portnoy
submission deadline 10 Dec 2025 | 1 articles | Viewed by 597 | Submission Open
Keywords: nanoparticles; drug delivery; liposomes; lipid nanoparticles; PLGA nanoparticles; PLA nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
edited by Robertas Lazauskas, Dalia Adukauskienė, and Inga Staneviciene
submission deadline 10 Dec 2025 | Viewed by 168 | Submission Open
Keywords: chitosan-based nanoparticles; oxidative stress; targeted drug delivery; biopharmaceutical applications; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Therapeutic Approaches for the Application of Natural Products in Skin Diseases submission deadline 11 Dec 2025 | Viewed by 342 | Submission Open
(This special issue belongs to the Section Biopharmaceutics)
Natural Products with Antimicrobial Activity and Their Pharmaceutical Delivery Systems submission deadline 15 Dec 2025 | 3 articles | Viewed by 2314 | Submission Open
Keywords: antibacterial; antiparasitic; antifungal; antiviral; natural compounds; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Methods of Potentially Improving Drug Permeation and Bioavailability
edited by Wihan Pheiffer, and
submission deadline 20 Dec 2025 | 6 articles | Viewed by 6223 | Submission Open
Keywords: drug permeation; bioavailablity enhancement; drug delivery systems; biological barriers; formulation strategies; in vivo; ex vivo; pharmacokinetics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements in Pro-Regenerative Hydrogel Scaffolds for Tissue Engineering and Regenerative Medicine
edited by and Dubravka P. Živanović
submission deadline 20 Dec 2025 | 2 articles | Viewed by 4852 | Submission Open
Keywords: pro-regenerative scaffolds for tissue engineering; ECM-like hydrogel substitutes; scaffolds for wound healing; scaffolds for bone and cartilage regeneration; scaffolds for nerve reparation; bioactive 3D scaffolds; scaffolds for engineering of 3D tumor tissue; multi-biofunctional scaffolds for tissue regeneration
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Chitosan-Based Nanoparticles for Drug Delivery
edited by Delia Mihaela Raţă
submission deadline 20 Dec 2025 | 2 articles | Viewed by 3655 | Submission Open
Keywords: nanoparticles; drug delivery systems; chitosan-coated liposomes; solid lipid nanoparticles; chitosan nanofibers; conjugated polymers; nanocomposites
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Phytocompounds-Based Formulations for Anti-Inflammatory Disorders
edited by Gustavo Costa
submission deadline 20 Dec 2025 | 1 articles | Viewed by 3323 | Submission Open
Keywords: phytocompounds; natural compounds; phytotherapy; plant-based drugs; anti-inflammatory; pharmaceutical forms
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Amorphous Solid Dispersions
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 866 | Submission Open
Keywords: amorphous solid dispersions; solubility enhancement; bioavailability; hot melt extrusion; ball milling; spray drying; freeze-drying; drug– polymer interactions; stability; pharmaceutical formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Nano-Formulations for Drug Delivery and Cancer Immunotherapy
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 834 | Submission Open
Keywords: nanomedicine; drug delivery systems; cancer immunotherapy; targeted therapy; nanoparticle design; tumor microenvironment; immune checkpoint blockade; combination therapy; stimuli-responsive carriers; clinical translation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Ocular Drug Delivery Systems and Formulations submission deadline 20 Dec 2025 | 1 articles | Viewed by 786 | Submission Open
Keywords: ocular drug delivery; ophthalmic formulations; ophthalmic drug bioavailability; ophthalmic hydrogels; ophthalmic pharmaceutical nanotechnology; ocular therapies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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