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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Engineering and Characterisation of Novel Nanomedicine Formulations, 2nd Edition

edited by

Ana Isabel Fraguas-Sánchez

Francisco Bolás-Fernández

and

Raquel Fernández García

submission deadline 25 Apr 2025 | 13 articles | Viewed by 17378 | Submission Open

Keywords: nanoparticles; liposomes; solid lipid nanocapsules; drug targeting; cancer; infectious diseases; nanovaccines

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Novel In Silico Supported Approaches for the Development and Delivery of Drugs for Antimicrobial Therapy and Neurodegenerative Diseases

edited by

Marko Jukić

submission deadline 25 Apr 2025 | Viewed by 311 | Submission Open

Keywords: antibacterials; antibiotics; chemotherapeutics; antivirals; antineurodegenerative; CADD; in silico drug design; drug delivery; in silico modeling; bioinformatics; machine learning; repurposing

(This special issue belongs to the Section Drug Targeting and Design)

Skin Care Products for Healthy and Diseased Skin

edited by Nina Dragićević

submission deadline 30 Apr 2025 | 9 articles | Viewed by 23770 | Submission Open

Keywords: skin care products; skin delivery; healthy skin; diseased skin; nanoparticle-based products; natural emulsifiers

(This special issue belongs to the Section Drug Targeting and Design)

Advances in Nanotechnology-Based Drug Delivery Systems

edited by Carla Serri

submission deadline 30 Apr 2025 | 8 articles | Viewed by 16960 | Submission Open

Keywords: biomaterials; nanomedicine; nanotechnology; formulations; green production technologies; biological macromolecule nanoencapsulation

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Biofunctional Pharmaceutical Additives for Targeted, Improved Bioavailability and Safety of Medicine

edited by

Hamdy Abdelkader

Adel Al-Fatease

and

Zimei Wu

submission deadline 30 Apr 2025 | 8 articles | Viewed by 15507 | Submission Open

Keywords: excipients; in situ forming polymers; modified-release; cyclodextrins; amino acids; eye diseases; diabetes; cancer

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Trends in mRNA Vaccine Development and Applications

edited by

Janos Szebeni

submission deadline 30 Apr 2025 | 2 articles | Viewed by 11318 | Submission Open

Keywords: vaccines; vaccination; modified mRNA; lipid nanoparticles (LNPs); mRNA-LNP; COVID-19 pandemic; SARS-CoV-2; spike protein; immunogenicity; adverse reactions

(This special issue belongs to the Section Gene and Cell Therapy)

3D Printing of Drug Delivery Systems

edited by

Djordje Medarevic

submission deadline 30 Apr 2025 | 6 articles | Viewed by 9360 | Submission Open

Keywords: additive manufacturing; 3D printing; personalized drug delivery systems; tailored drug release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Self-Assembled Amphiphilic Copolymers in Drug Delivery, 2nd Edition

edited by

Ana Cazacu

and

Elena-Laura Ursu

submission deadline 30 Apr 2025 | 5 articles | Viewed by 9271 | Submission Open

Keywords: self-assembly; amphiphilic block copolymers; nanostructures; drug delivery systems; targeted drug delivery; controlled release; kinetics studies; carriers; micelles; polymersomes

(This special issue belongs to the Section Drug Targeting and Design)

Advances in Pharmacokinetics, Pharmacodynamics and Drug Interactions, 2nd Edition

edited by

Kyeong-Ryoon Lee

and

Yoon-Jee Chae

submission deadline 30 Apr 2025 | 4 articles | Viewed by 8564 | Submission Open

Keywords: pharmacokinetics; pharmacodynamics; PK/PD modeling; drug– drug interactions; PBPK model; drug delivery; drug development

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Drug Delivery of Natural Active Principles: Focus on Topical and Oral Applications, 2nd Edition

edited by

Marta Miola

and

Marta Gallo

submission deadline 30 Apr 2025 | 5 articles | Viewed by 8491 | Submission Open

Keywords: natural compounds; topical drug delivery; oral drug delivery; micro- and nano-particles; polymer-; lipid-; oxide-based and hybrid systems; synthesis and characterization; in vitro; in vivo tests

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Mechanism-Based Pharmacokinetic and Pharmacodynamic Modeling

edited by

Artur Świerczek

submission deadline 30 Apr 2025 | 5 articles | Viewed by 6208 | Submission Open

Keywords: PK/PD modeling; disease progression modeling; quantitative system pharmacology; physiologically based modeling

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Kinase Inhibitor for Cancer Therapy, 2nd Edition

edited by

Francesca Musumeci

submission deadline 30 Apr 2025 | 2 articles | Viewed by 5583 | Submission Open

Keywords: kinase inhibitor; cancer; targeted therapy; small molecule; monoclonal antibody; drug delivery; formulation studies

(This special issue belongs to the Section Drug Targeting and Design)

Advances in Pharmacokinetics and Drug Interactions

edited by Stephan Schmidt,

Natalia V. De Moraes

and

Vanessa Bergamin Boralli

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4852 | Submission Open

Keywords: pharmacokinetics; drug interactions; PBPK modeling; drug delivery systems; personalized medicine

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Advances in Polymeric Drug Delivery Systems, 2nd Edition

edited by

Joanna Rydz

and

Barbara Zawidlak-Węgrzyńska

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4622 | Submission Open

Keywords: drug delivery; controlled release; biopolymers; nanopolymers; nanoparticles; (bio)degradable polymers; synthetic polymers; 3D printing; personalized medicine

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanosystems and Antibody/Peptide Modified Drugs for Cancer Treatment

edited by

Juan Manuel López Romero

and

Francisco Sarabia

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4600 | Submission Open

Keywords: antibody; peptide; vectorized drugs; nanocarriers; engineered drugs; improved drug delivery

(This special issue belongs to the Section Drug Targeting and Design)

Therapeutic Drugs and Delivery Strategies for Gastrointestinal Diseases

edited by

Michael A. Firer

and

Hengqi Zheng

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2995 | Submission Open

Keywords: targeted therapy in drug delivery; biologic therapies in inflammatory bowel disease (e.g.; special dosages; administration and delivery); biologic therapies in eosinophilic esophagitis (e.g.; special dosages; administration and delivery); eosinophilic gastrointestinal disease

(This special issue belongs to the Section Clinical Pharmaceutics)

Cyclodextrin-Based Gene and Drug Delivery Applications

edited by

Francesco Trotta

and

Yousef Khazaei Monfared

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2757 | Submission Open

Keywords: cyclodextrin; gene delivery; drug delivery; nanocarriers; biocompatibility; controlled release; targeted therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Drug Delivery across the Blood–Brain Barrier

edited by

Kun Cheng

and Zhen Zhao

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2655 | Submission Open

Keywords: blood– brain barrier (BBB); central nervous system (CNS); drug delivery; neurological disease; nanotechnology; transport mechanism; targeted delivery; BBB permeability; glioblastoma

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing

edited by Carolina Martinez and María Jimena Prieto

submission deadline 30 Apr 2025 | 3 articles | Viewed by 2399 | Submission Open

Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Recent Advances in Pharmaceutical Applications of Functionalized Polysaccharides and Their Derivatives, 2nd Edition

edited by

Peter Foot

Elena Polycarpou

and Federico Buonocore

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2389 | Submission Open

Keywords: functionalized polysaccharides ; nanoparticle characterization; drug delivery; enhanced loading capacity; controlled release properties; anti-microbial and anti-cancer activities; wound management

(This special issue belongs to the Section Biopharmaceutics)

Enhancing Drug Delivery with Bioactive Substances and Solid Dispersion

edited by

Marco Chaud

and Fernanda Isadora Boni

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2294 | Submission Open

Keywords: solid dispersion; amorphous solid dispersion; solid dispersion bioavailability; solid dispersion characterization; ternary solid dispersion; binary solid dispersion

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Exploring the Versatility of Cyclodextrins in Pharmaceutical Formulations

edited by

Łukasz Szeleszczuk

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1957 | Submission Open

Keywords: cyclodextrins; CDs; inclusion complexes; cyclodextrin-based nanosponges; excipients; host– guest complexes; complexes

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Biotechnology Applications and Innovative Approaches for Cancer Prevention and Treatment (BIO-APP)

edited by

and

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1877 | Submission Open

Keywords: applied biochemistry; biotechnologies; cancer; drug delivery; multitarget ligands; theranostics; biomarkers; point-of-care testing; sensitive nanomaterials

(This special issue belongs to the Section Biologics and Biosimilars)

Current Research on Polymeric Nanoparticles for Drug Delivery Applications

edited by Simeon Kolawole Adesina and Funmilola Adesodun Fisusi

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1815 | Submission Open

Keywords: polymeric micelles; dendrimers; nanocapsules; nanospheres

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advanced In Silico Methods and Digital Platforms for the Prediction of ADMET and Pharmacokinetics Properties

edited by

Nicola Gambacorta

and

Daniela Trisciuzzi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1790 | Submission Open

Keywords: ADMET properties prediction; physiologically based pharmacokinetic (PBPK) modeling; in silico digital platform; chemoinformatics; computer-aided drug discovery; predictive toxicology

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Microneedles for Drug and Vaccine Delivery

edited by

Hiep (Ben) Nguyen

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1700 | Submission Open

Keywords: physical enhancement technologies; fabrication; characterization; applications; drug delivery; cosmetic applications; diagnostic; vaccination

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nano-Based Technology for Glioblastoma

edited by

Maria João Ramalho

and Joana Peixoto

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1657 | Submission Open

Keywords: nanoparticles; glioblastoma; blood– brain barrier; diagnosis; therapy; drug delivery; nose-to-brain delivery; targeted delivery; surface modification

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances in Formulation of Nanocarriers for Overcoming Biological Barriers

edited by

Sandra Elisa Haas

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1436 | Submission Open

Keywords: biological barriers; drug delivery; nanocarriers; pharmacokinetics; toxicology; pharmacodynamics

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Hybrid Nanoparticles for Cancer Therapy

edited by Jacy Gameiro

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1378 | Submission Open

Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Application of Silver Nanoparticles in Cancer Treatment

edited by

Serena Mazzucchelli

and Francesco Ragonese

submission deadline 30 Apr 2025 | 1 articles | Viewed by 794 | Submission Open

Keywords: silver nanoparticles; nanomedicine; nanotechnology; cancer therapy; cancer diagnostics; cancer theranostics; tumor targeting; drug delivery systems; in vitro studies; in vivo studies

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Gene Therapy with LNPs, Possibilities, Limitations, New Strategies

edited by Jason Duskey and

Ilaria Ottonelli

submission deadline 30 Apr 2025 | Viewed by 465 | Submission Open

Keywords: gene therapy; lipid nanoparticles; nucleic acid delivery; nuclear targeted LNPs; microfluidic production of LNPs

(This special issue belongs to the Section Gene and Cell Therapy)

Recent Advances in Drug Formulation for Antiviral Therapy

edited by Chiara Medaglia

submission deadline 30 Apr 2025 | Viewed by 302 | Submission Open

Keywords: antiviral drugs development; infection; host-pathogen interactions; functional genomics

(This special issue belongs to the Section Drug Targeting and Design)

Nanoemulsions for Nose-to-Brain Drug Delivery

edited by Clóvis Orlando Pereira Da Fonseca and

Rubiana Mara Mainardes

submission deadline 30 Apr 2025 | Viewed by 242 | Submission Open

Keywords: nanoemulsion; intranasal; pharmacokinetics; nose-to-brain; neurology; olfactory; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Innovations in Drug Delivery, Pharmacometrics, and Clinical Studies in Veterinary Medicine

edited by

Eryvaldo Sócrates Tabosa Do Egito

Frederico Severino Martins

and Marcos Ferrante

submission deadline 30 Apr 2025 | Viewed by 210 | Submission Open

Keywords: veterinary medicine; pharmacometrics; PK/PD modeling; drug delivery; dose optimization

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Advances in Drug Delivery Systems for Leishmaniasis Therapy

edited by Elizabeth Igne Ferreira, Jeanine Giarolla and Soraya Da Silva Santos

submission deadline 30 Apr 2025 | Viewed by 183 | Submission Open

Keywords: delivery systems; leishmanicides; bioactive compounds in Leishmania sp.; advanced systems for drug delivery; oral and topical administration

(This special issue belongs to the Section Drug Targeting and Design)

Design of Hydrogels for Drug Delivery

edited by

Luis Morales-Quintana

and

Bustos Daniel

submission deadline 30 Apr 2025 | Viewed by 161 | Submission Open

Keywords: drug delivery; controlled release; smart hydrogels; computational modelling of hydrogels; molecular simulations of hydrogels; bioresponsive systems; hydrogel fabrication techniques

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advancing Block Co-Polymer Nanomedicines: Innovations in Effective Drug Delivery

edited by

Giulia Bonacucina

and

Nisar Ul Khaliq

submission deadline 30 Apr 2025 | Viewed by 161 | Submission Open

Keywords: pluronic-based nanomedicines and hydrogels; gene delivery; advanced drug delivery systems; radiotherapy and photodynamic therapy; combination therapy; polymeric nanomedicines; immunotherapy; nanogels; small-molecule delivery systems; block co-polymers nanomedicines

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances and Challenges in Nasal Formulation Developments, 2nd Edition

edited by

Daisuke Inoue

submission deadline 10 May 2025 | 8 articles | Viewed by 26120 | Submission Open

Keywords: nasal formulations; intranasal dissolution and permeation; mucosal absorption; excipients for nasal formulations; in vitro dissolution system; in vivo nasal dissolution and absorption

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Dosage Form Design for Oral Administration

edited by

Atheer Awad

and

Hend Abdelhakim

submission deadline 10 May 2025 | 5 articles | Viewed by 11257 | Submission Open

Keywords: controlled release; nanotechnology; peptide and protein; buccal; age-appropriate; taste; packaging; mini-tablets; quality by design; veterinary medicine

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Development of Novel Tumor-Targeting Nanoparticles, 2nd Edition

edited by

Andrea Lancia

Alexander Zaboronok

and

Bryan Mathis

submission deadline 10 May 2025 | 5 articles | Viewed by 8961 | Submission Open

Keywords: nanoparticles; nanoliposomes; nanomicelles; tumor targeting; drug delivery system; cancer; theranostics

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Biopolymer-Based Nanosystem for Drug Delivery, 2nd Edition

edited by

Ildikó Bácskay

and

János Borbély

submission deadline 10 May 2025 | 4 articles | Viewed by 8255 | Submission Open

Keywords: nano-formulations of drugs; antibody drug conjugation (ADC); nanoformulated vaccines; delivery of biologics; biotech risk analysis; assessment of biocompatibility; drug delivery system formulation; characterization of dosage forms; in vitro dissolution studies; SEDDS

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Pharmaceutical Excipients Used in Solid Dosage Forms

edited by

Ivana Aleksić

and

Jelena Djuris

submission deadline 10 May 2025 | 5 articles | Viewed by 8104 | Submission Open

Keywords: solid dosage forms; co-processed excipients; mesoporous materials; multifunctional excipients; directly compressible; high-functionality excipients; bioavailability enhancement; continuous processing; patient compliance; sustainability; poor solubility

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Advances in Anticancer Agent, 2nd Edition

edited by

Noelia Duarte

and

Ana Paula Francisco

submission deadline 10 May 2025 | 4 articles | Viewed by 7304 | Submission Open

Keywords: synthetic/natural anticancer agents; drug design; targeted therapies; hybrid compounds; metastasis; multidrug resistance

(This special issue belongs to the Section Drug Targeting and Design)

Phytocompounds-Based Formulations for Anti-Inflammatory Disorders

edited by Gustavo Costa

submission deadline 10 May 2025 | 1 articles | Viewed by 637 | Submission Open

Keywords: phytocompounds; natural compounds; phytotherapy; plant-based drugs; anti-inflammatory; pharmaceutical forms

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Nanoparticle-Based Drug Formulation for Enhancing Nose-to-Brain Delivery

edited by

Jagdish Singh

and Richard Nii Lante Lamptey

submission deadline 10 May 2025 | Viewed by 299 | Submission Open

Keywords: nanoparticles; nose-to-brain drug delivery; blood– brain barrier (BBB); central nervous system (CNS); neurodegenerative diseases; targeted therapeutics; non-invasive delivery; intranasal administration

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications

edited by

Dong‑Gyun Han

submission deadline 15 May 2025 | 1 articles | Viewed by 962 | Submission Open

Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Stability of Medicines and Novel Approaches for Predicting Drug Stability

edited by

Dolores R. Serrano

and

Juan José Torrado Durán

submission deadline 20 May 2025 | 10 articles | Viewed by 43638 | Submission Open

Keywords: stability; 3D printing; ICH; physical stability; biologicals

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Nucleic-Acid-Based Strategies and Nanotechnology Applications for Targeted Therapy

edited by

Andrea Patrizia Falanga

Stefano D’Errico

and

Monica Terracciano

submission deadline 20 May 2025 | 9 articles | Viewed by 21041 | Submission Open

Keywords: nucleic acids; drug delivery; nanomedicine; biotechnology; material science.

(This special issue belongs to the Section Drug Targeting and Design)

Where Are We Now and Where Is Cell Therapy Headed?

edited by

Andrea Papait

and

Paola Chiodelli

submission deadline 20 May 2025 | 8 articles | Viewed by 17291 | Submission Open

Keywords: stem cells; mesenchymal stromal cells; cell therapy; CAR-T; CAR-NK; cancer; gene therapy; organoids and organ on a chip; extracellular vesicles; secretome

(This special issue belongs to the Section Gene and Cell Therapy)

Natural Nanoparticle for Cancer Diagnosis and Treatment, 2nd Edition

edited by

Serena Mazzucchelli

submission deadline 20 May 2025 | 6 articles | Viewed by 15005 | Submission Open

Keywords: natural nanoparticles; drug delivery; tumor-targeting probes

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

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