Bioactive Polymer Materials with Antibacterial Properties, 2nd Edition

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 876

Special Issue Editors


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Guest Editor
Department of Food and Nutrition, College of Biotechnology and Natural Resource, Chung-Ang University, Anseong 17546, Gyeonggi‑do, Republic of Korea
Interests: bioactive materials; nanoparticles; multidrug-resistant microorganisms
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Guest Editor
Department of Food Science and Biotechnology, Gachon University, Seongnam 461-701, Republic of Korea
Interests: antimicrobial agents; nanomaterials; food safety
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Guest Editor
National Institutes of Health (NIH), Bethesda, MD 20892, USA
Interests: biofilm; antibacterial; antibiotic resistant; infectious diseases

Special Issue Information

Dear Colleagues,

This Special Issue entitled “Bioactive Materials with Antibacterial Properties” is devoted to the dissemination of high-quality original research articles or comprehensive reviews. Bioactive materials have a wide range of applications. Bioactive materials with antibacterial properties have attracted significant medical interest. Antibacterial bioactive materials can be obtained from nature or they can be synthesized in different ways. They can be prepared by the simple combination of antibacterial substances with materials such as metals or polymers. The delivery of these bioactive materials kills pathogenic bacteria. Due to the uncontrolled, immoderate and multiple uses of antibiotics and chemotherapeutics, the emergence of multidrug-resistant (MDR) bacteria is a serious threat to the world population. The development of a new antibacterial agent is the decisive solution for this issue. Therefore, bioactive materials with antibacterial properties could be promising agents to control these MDR bacteria. 

We would like to invite researchers to contribute to this Special Issue. Research topics of interest cover (but are not limited to) one or several of the following topics: synthesis/biosynthesis of different bioactive materials; natural compounds with antibacterial properties; synthesis of various nanoparticles with antibacterial properties; anti-biofilm activity; mode of action; mechanisms of antibacterial activity. 

Dr. Md. Amdadul Huq
Dr. Shahina Akter
Dr. Md. Ashrafudoulla
Guest Editors

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Keywords

  • bioactive materials
  • antibacterial properties
  • nanoparticles
  • anti-biofilm activity
  • mechanisms of antibacterial activity

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Published Papers (1 paper)

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Research

20 pages, 5784 KiB  
Article
Alginate Extracted from Azotobacter chroococcum Loaded in Selenium Nanoparticles: Insight on Characterization, Antifungal and Anticancer Activities
by Hebah A. Sindi, Ragaa A. Hamouda, Marwa S. Abdel-Hamid and Nuha M. Alhazmi
Polymers 2024, 16(14), 2065; https://doi.org/10.3390/polym16142065 - 19 Jul 2024
Viewed by 528
Abstract
Cancer is a threatening disease that needs strong therapy with fewer side effects. A lot of different types of chemotherapy or chemo-drugs are used in cancer treatments but have many side effects. The increasing number of antibiotic-resistant microorganisms requires more study of new [...] Read more.
Cancer is a threatening disease that needs strong therapy with fewer side effects. A lot of different types of chemotherapy or chemo-drugs are used in cancer treatments but have many side effects. The increasing number of antibiotic-resistant microorganisms requires more study of new antimicrobial compounds and delivery and targeting strategies. This work aims to isolate and identify Azotobacter sp., and extract alginate from Azotobacter sp. As well as fabricating selenium nanoparticles using ascorbic acid as reducing agent (As/Se-NPs), and loading extracted alginate with selenium nanoparticles (Alg-Se-NCMs). The As/Se-NPs and Alg-Se-NCMs were categorized by TEM, EDX, UV–Vis spectrophotometry, FT-IR, and zeta potential. The antifungal activities of both As/Se-NPs and Alg-Se-NCMs were investigated against some human pathogen fungi that cause skin infection such as Aspergillus niger (RCMB 002005), Aspergillus fumigatus (RCMB 002008), Cryptococcus neoformans (RCMB 0049001), Candida albicans (RCMB 005003), and Penicillium marneffei (RCMB 001002). The anticancer activities were determined against HCT-116 colorectal cancer and Hep G2 human liver cancer cells. UV spectra of As/Se-NPs and Alg-Se-NCMs confirmed a surface plasmon resonance at 269 and 296 nm, and zeta potential has negative charges −37.2 and −38.7 mV,. Both As/Se-NPs and Alg-Se-NCMs were hexagonal, size ranging from 16.52 to 97.06 and 17.29 to 44.2. Alg-Se-NCMs had anticancer activities against HCT-116 and HepG2. The Alg-Se-NCMs possessed the highest antifungal activities against Cryptococcus neoformans, followed by Aspergillus niger, but did not possess any activities against Penicillium marneffei. Alginate-capped selenium nanoparticles can be used as antifungal and anticancer treatments. Full article
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