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Editorial Board Members' Collection Series: Recent Developments in Electrospinning

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (20 May 2024) | Viewed by 8963

Special Issue Editors


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Guest Editor
Faculty of Engineering and Mathematics, Bielefeld University of Applied Sciences and Arts, Interaktion 1, 33619 Bielefeld, Germany
Interests: biopolymers; electrospinning; magnetism; spintronics; optics; dye-sensitized solar cells (DSSCs); smart textiles
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Guest Editor
1. Head of the Laboratory of Natural Polymers, Institute of Macromolecular Compounds of the Russian Academy of Sciences, St. Petersburg, Russia
2. Head of the Analytical Chemistry Department, Almazov National Medical Research Centre, St. Petersburg, Russia
Interests: polysaccharides; biomaterials; tissue engineering; drug delivery; gene delivery; nanomedicine; nanocomposites; electrospinning
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Food Engineering Research Institute (FoodUPV), Universitat Politècnica de València (UPV), Camino de Vera s/n, 46022 Valencia, Spain
Interests: bio-based and biodegradable polymers; green composites; polymerization of biopolymers; processing of bioplastics; nanofibers obtained by electrospinning; sustainable polymer technologies for food preservation; controlled release of active compounds in plastic formulations; biopolymers for food packaging; bioeconomy; circular economy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
N. N. Semenov Federal Research Center for Chemical Physics Academy of Science, 119991 Moscow, Russia
Interests: biodegradable polymers; transport phenomena; electrospun fibers; controlled release; polymer blends; composites; water in macromolecular systems; sorption; gas permeability
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Special Issue "Editorial Board Members' Collection Series: Recent Developments in Electrospinning" is triggered by the growing interest in the development, fabrication, and application of electrospinning materials in various fields, including tissue engineering, regenerative medicine, wound healing, drug and gene delivery, cosmetics, packaging, textile manufacturing, filtration, environmental  remediation, catalysis, among others. The aim of this Special Issue is to provide broad coverage of research progress as well as current literature reviews on fundamental and applied aspects of electrospinning for various applications. 

We invite active experts to participate in discussions on improvements in electrospinning technologies and innovations in electrospun polymers and polymeric composites. We hope that this Special Issue will provide a unique platform for disseminating new concepts and applications of electrospinning toward inspiring and motivating further research in this exciting field.

Prof. Dr. Andrea Ehrmann
Dr. Yury A. Skorik
Dr. Francesco Lopresti
Prof. Dr. Sergio Torres-Giner
Prof. Dr. Alexey L. Iordanskii 
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • electrospinning process design
  • electrospun materials
  • nanomaterials
  • ultrathin materials
  • tissue engineering
  • regenerative medicine
  • drug and gene delivery
  • wound healing
  • environmental remediation
  • filtration
  • enzyme immobilization
  • catalysis
  • packaging
  • cosmetics
  • non-woven textile

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Published Papers (5 papers)

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Research

21 pages, 3652 KiB  
Article
Biocomposites Based on Electrospun Fibers of Poly(3-hydroxybutyrate) and Nanoplatelets of Graphene Oxide: Thermal Characteristics and Segmental Dynamics at Hydrothermal and Ozonation Impact
by Svetlana G. Karpova, Anatoly A. Olkhov, Ivetta A. Varyan, Natalia G. Shilkina, Alexander A. Berlin, Anatoly A. Popov and Alexey L. Iordanskii
Polymers 2023, 15(20), 4171; https://doi.org/10.3390/polym15204171 - 20 Oct 2023
Viewed by 1427
Abstract
In order to create new biodegradable nanocomposites for biomedicine, packaging, and environmentally effective adsorbents, ultra-thin composite fibers consisting of poly(3-hydroxybutyrate) (PHB) and graphene oxide (GO) were obtained by electrospinning. Comprehensive studies of ultrathin fibers combining thermal characteristics, dynamic electron paramagnetic resonance (ESR) probe [...] Read more.
In order to create new biodegradable nanocomposites for biomedicine, packaging, and environmentally effective adsorbents, ultra-thin composite fibers consisting of poly(3-hydroxybutyrate) (PHB) and graphene oxide (GO) were obtained by electrospinning. Comprehensive studies of ultrathin fibers combining thermal characteristics, dynamic electron paramagnetic resonance (ESR) probe measurements, and scanning electron microscopy (SEM) were carried out. It is shown that at the addition of 0.05, 0.1, 0.3, and 1% OG, the morphology and geometry of the fibers and their thermal and dynamic characteristics depend on the composite content. The features of the crystalline and amorphous structure of the PHB fibers were investigated by the ESR and DSC methods. For all compositions of PHB/GO, a nonlinear dependence of the correlation time of molecular mobility TEMPO probe (τ) and enthalpy of biopolyether melting (ΔH) is observed. The influence of external factors on the structural-dynamic properties of the composite fiber, such as hydrothermal exposure of samples in aqueous medium at 70 °C and ozonolysis, leads to extreme dependencies of τ and ΔH, which reflect two processes affecting the structure in opposite ways. The plasticizing effect of water leads to thermal destruction of the orientation of the pass-through chains in the amorphous regions of PHB and a subsequent decrease in the crystalline phase, and the aggregation of GO nanoplates into associates, reducing the number of GO-macromolecule contacts, thus increasing segmental mobility, as confirmed by decreasing τ values. The obtained PHB/GO fibrillar composites should find application in the future for the creation of new therapeutic and packaging systems with improved biocompatibility and high-barrier properties. Full article
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16 pages, 4795 KiB  
Article
Hydrogen Bond-Induced Activation of Photocatalytic and Piezophotocatalytic Properties in Calcium Nitrate Doped Electrospun PVDF Fibers
by F. F. Orudzhev, D. S. Sobola, Sh. M. Ramazanov, K. Častková, D. A. Selimov, A. A. Rabadanova, A. O. Shuaibov, R. R. Gulakhmedov, M. G. Abdurakhmanov and K. M. Giraev
Polymers 2023, 15(15), 3252; https://doi.org/10.3390/polym15153252 - 30 Jul 2023
Cited by 7 | Viewed by 2251
Abstract
In this study, polyvinylidene fluoride (PVDF) fibers doped with hydrated calcium nitrate were prepared using electrospinning. The samples were analyzed using scanning electron microscopy (SEM), X-ray diffraction (XRD), optical spectroscopy, X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FTIR), Raman, and photoluminescence (PL) spectroscopy. [...] Read more.
In this study, polyvinylidene fluoride (PVDF) fibers doped with hydrated calcium nitrate were prepared using electrospinning. The samples were analyzed using scanning electron microscopy (SEM), X-ray diffraction (XRD), optical spectroscopy, X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FTIR), Raman, and photoluminescence (PL) spectroscopy. The results are complementary and confirm the presence of chemical hydrogen bonding between the polymer and the dopant. Additionally, there was a significant increase in the proportion of the electroactive polar beta phase from 72 to 86%. It was shown that hydrogen bonds acted as a transport pathway for electron capture by the conjugated salt, leading to more than a three-fold quenching of photoluminescence. Furthermore, the optical bandgap of the composite material narrowed to the range of visible light energies. For the first time, it the addition of the salt reduced the energy of the PVDF exciton by a factor of 17.3, initiating photocatalytic activity. The calcium nitrate-doped PVDF exhibited high photocatalytic activity in the degradation of methylene blue (MB) under both UV and visible light (89 and 44%, respectively). The reaction rate increased by a factor of 2.4 under UV and 3.3 under visible light during piezophotocatalysis. The catalysis experiments proved the efficiency of the membrane design and mechanisms of catalysis are suggested. This study offers insight into the nature of chemical bonds in piezopolymer composites and potential opportunities for their use. Full article
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20 pages, 4553 KiB  
Article
Electrospun Scaffolds Enriched with Nanoparticle-Associated DNA: General Properties, DNA Release and Cell Transfection
by Vera Chernonosova, Marianna Khlebnikova, Victoriya Popova, Ekaterina Starostina, Elena Kiseleva, Boris Chelobanov, Ren Kvon, Elena Dmitrienko and Pavel Laktionov
Polymers 2023, 15(15), 3202; https://doi.org/10.3390/polym15153202 - 27 Jul 2023
Cited by 2 | Viewed by 1550
Abstract
Biomaterial-mediated, spatially localized gene delivery is important for the development of cell-populated scaffolds used in tissue engineering. Cells adhering to or penetrating into such a scaffold are to be transfected with a preloaded gene that induces the production of secreted proteins or cell [...] Read more.
Biomaterial-mediated, spatially localized gene delivery is important for the development of cell-populated scaffolds used in tissue engineering. Cells adhering to or penetrating into such a scaffold are to be transfected with a preloaded gene that induces the production of secreted proteins or cell reprogramming. In the present study, we produced silica nanoparticles-associated pDNA and electrospun scaffolds loaded with such nanoparticles, and studied the release of pDNA from scaffolds and cell-to-scaffold interactions in terms of cell viability and pDNA transfection efficacy. The pDNA-coated nanoparticles were characterized with dynamic light scattering and transmission electron microscopy. Particle sizes ranging from 56 to 78 nm were indicative of their potential for cell transfection. The scaffolds were characterized using scanning electron microscopy, X-ray photoelectron spectroscopy, stress-loading tests and interaction with HEK293T cells. It was found that the properties of materials and the pDNA released vary, depending on the scaffold’s composition. The scaffolds loaded with pDNA-nanoparticles do not have a pronounced cytotoxic effect, and can be recommended for cell transfection. It was found that (pDNA-NPs) + PEI9-loaded scaffold demonstrates good potential for cell transfection. Thus, electrospun scaffolds suitable for the transfection of inhabiting cells are eligible for use in tissue engineering. Full article
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16 pages, 13312 KiB  
Article
Effect of Recombinant Spidroins Self-Assembly on Rheological Behavior of Their Dispersions and Structure of Electrospun Nanofibrous Materials
by Timur Kh. Tenchurin, Roman V. Sharikov, Sergei I. Belousov, Dmitry R. Streltsov, Sergey N. Malakhov, Evgeny V. Yastremsky, Yuri M. Chesnokov, Lyubov I. Davydova, Vladimir G. Bogush and Sergei N. Chvalun
Polymers 2023, 15(14), 3001; https://doi.org/10.3390/polym15143001 - 10 Jul 2023
Viewed by 1342
Abstract
The effect of primary amino acid sequence in recombinant spidroins on their spatial organization is crucial for the fabrication of artificial fibers and fibrous materials. This study focuses on the rheological properties of aqueous and alcoholic solutions of recombinant analogs of natural spidroins [...] Read more.
The effect of primary amino acid sequence in recombinant spidroins on their spatial organization is crucial for the fabrication of artificial fibers and fibrous materials. This study focuses on the rheological properties of aqueous and alcoholic solutions of recombinant analogs of natural spidroins (rS1/9 and rS2/12), as well as the structure of their films and nanofibrous materials. Non-Newtonian flow behavior of aqueous solutions of these proteins was observed at certain concentrations in contrast to their solutions in hexafluoroisopropanol. The secondary structure of recombinant spidroins was addressed by IR spectroscopy, whereas their self-organization in various solvents was studied by AFM and cryo-TEM. The influence of the solvent on the structure and properties of the films and nanofibrous materials produced by electrospinning has been established. Full article
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17 pages, 3721 KiB  
Article
Electrospun Poly-L-Lactic Acid Scaffolds Surface-Modified via Reactive Magnetron Sputtering Using Different Mixing Ratios of Nitrogen and Xenon
by Pavel V. Maryin, Tuan-Hoang Tran, Anastasia A. Frolova, Mikhail A. Buldakov, Evgeny L. Choinzonov, Anna I. Kozelskaya, Sven Rutkowski and Sergei I. Tverdokhlebov
Polymers 2023, 15(13), 2969; https://doi.org/10.3390/polym15132969 - 6 Jul 2023
Cited by 4 | Viewed by 1521
Abstract
Controlled regeneration processes involving tissue growth using the surface and structure of scaffolds, are actively used in tissue engineering. Reactive magnetron sputtering is a versatile surface modification method of both metal and polymer substrates, as the properties of the formed coatings can be [...] Read more.
Controlled regeneration processes involving tissue growth using the surface and structure of scaffolds, are actively used in tissue engineering. Reactive magnetron sputtering is a versatile surface modification method of both metal and polymer substrates, as the properties of the formed coatings can be modified in a wide range by changing the process parameters. In magnetron sputtering, the working gas and its composition have an influence on the chemical composition and physical characteristics of the obtained coatings. However, there are no studies addressing the influence of the nitrogen/xenon gas mixture ratio in direct current magnetron sputtering on the deposition rate, physicochemical and in vitro properties of surface-modified biocompatible poly-L-lactic acid scaffolds. In this study, the application of mixtures of nitrogen and xenon in various ratios is demonstrated to modify the surface of non-woven poly-L-lactic acid scaffolds by direct current magnetron sputtering of a titanium target. It has been found that the magnetron sputtering parameters chosen do not negatively influence the morphology of the prepared scaffolds, but increase the hydrophilicity. Moreover, quantitative spectroscopic analysis results indicate that the formed coatings are primarily composed of titanium oxide and titanium oxynitride compounds and is dependent on the gas mixture ratio only to a certain extent. Atomic force microscopy investigations of the roughness of the fibers of the electrospun scaffolds and the thickness of the coatings formed on them show that the considerable variations observed in the intrinsic fiber reliefs are due to the formation of a fine layer on the fiber surfaces. The observed decrease in roughness after plasma modification is due to temperature and radiation effects of the plasma. In vitro experiments with human osteosarcoma cells show that the scaffolds investigated here have no cytotoxic effect on these cells. The cells adhere and proliferate well on each of the surface-modified electrospun scaffolds, with stimulation of cell differentiation in the osteogenic direction. Full article
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