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Polymers
Special Issues
Advances and Applications of Molecularly Imprinted Polymers
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Advances and Applications of Molecularly Imprinted Polymers

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (15 April 2023) | Viewed by 1716

Special Issue Editor

Dr. M. E. Abd El-Aziz

E-Mail Website
Guest Editor
Polymers & Pigments Department, National Research Center, Giza 12622, Egypt
Interests: polymers; biopolymers; nanocomposite; nanomaterials; composite

Special Issue Information

Dear Colleagues,

Polymers are among the materials that impress scientists for their unique properties and the possibility of using them in all aspects of life. Recent years have witnessed great progress in the manufacture of polymers. there are various types of the polymers such as biopolymers, polymers composites, polymers nanocomposites, polymer blends, etc. Smart polymers are one of the most important modern polymer products. This is due to its ability to sense the changes that occur in the surroundings such as a change in temperature, humidity, pH, etc.

Molecularly imprinted polymers (MIPs) are considered the most important type of smart polymers that have artificial receptors for a target molecule, where their synthetic receptors imitative to natural antibodies and enzymes in their function, the mode of action, and ability of recognition. They can be used in several applications such as sensors, membranes, drug delivery, etc. There is a particular interest in designing smart MIPs. The intelligence of these polymers stems from their response to an external stimuli such as temperature, pH, biomolecule, and magnetic field which induced more advanced applications for the MIPs.

Dr. M. E. Abd El-Aziz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • smart polymers
  • molecularly imprinting polymers
  • functional polymers

Published Papers (1 paper)

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Research

12 pages, 1997 KiB  
Article
DNA-Immobilized Special Conformation Recognition of L-Penicillamine Using a Chiral Molecular Imprinting Technique
by Lianming Zhang, Kui Luo, Jingxia Gao and Jianping Li
Polymers 2022, 14(19), 4133; https://doi.org/10.3390/polym14194133 - 2 Oct 2022
Viewed by 1447
Abstract
A new chiral molecularly imprinted polymer (MIP) sensor with dual recognition ability was developed for the highly selective separation of enantiomers with toxic side effects in drugs. The sensor contains double-stranded deoxyribonucleic acid (dsDNA) as the element that immobilizes the chiral molecular conformation: [...] Read more.
A new chiral molecularly imprinted polymer (MIP) sensor with dual recognition ability was developed for the highly selective separation of enantiomers with toxic side effects in drugs. The sensor contains double-stranded deoxyribonucleic acid (dsDNA) as the element that immobilizes the chiral molecular conformation: the dsDNA enables the imprinted cavities to match the three-dimensional structure and functional groups from the chiral molecule. By embedding the spatial orientation of dsDNA in MIPs, one can accurately capture and immobilize the molecular conformation, eliminating the influence of interfering analogues. Herein, L-penicillamine (L-Pen) was selected as the chiral template molecule and embedded into dsDNA to form dsDNA-L-Pen complex, which was then embedded into the MIPs by electropolymerization. After elution, the stereo-selective imprinted cavities were obtained. The ATATATATATAT-TATATATATATA base sequence showed a high affinity for the embedded L-Pen, which endowed the imprinted cavities with a larger number of sites and improved the selectivity toward Pen enantiomers. Under the optimal working conditions, the current response of the MIP/dsDNA sensor exhibited a positive linear relationship with the logarithm of the L-Pen concentration in the range of 3.0 × 10−16 to 3.0 × 10−13 mol/L, and the detection limit was 2.48 × 10−16 mol/L. After the introduction of dsDNA into the MIP, the selectivity of the sensor toward D-Pen increased by 6.4 times, and the sensor was successfully applied in the analysis of L-Pen in penicillamine tablets. Full article
(This article belongs to the Special Issue Advances and Applications of Molecularly Imprinted Polymers)
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