Advanced Dendritic and Hyperbranched Polymers
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3714
Special Issue Editors
Interests: nanomaterials with antimicrobial properties; nanocarriers of antimicrobial proteins; polymer modification of proteins; toxicity of nanomaterials
Special Issue Information
Dear Colleagues,
Antibacterial resistance has become a global threat; of particular importance are multidrug-resistant (MDR) bacteria, with a broad spectrum of virulence factors. Multidrug resistance is overrepresented in Gram-negative bacteria, where the outer and inner membranes are effective barriers against most antibacterial agents. Recently, there has been a noticeable trend towards targets in the outer membrane in preclinical projects. Most solutions are currently focused on finding the best permeabilizer of the bacterial membrane as the main mechanism of action to kill bacteria. Recent studies have shown the great potential of dendritic polymers, which may represent a new class of bacterial membrane permeabilizers. In this regard, the mechanisms of permeabilization of the outer bacterial membrane due to dendritic and hyperbranched polymers have now become of significant interest. We believe that knowledge of how dendritic polymers disrupt the bacterial membrane to carry out antibacterial activities is crucial in order to further develop potent and effective antibacterial agents.
For this Special Issue, we invite submissions in the form of manuscripts focusing on dendritic and hyperbranched polymers that could be applied in biomedicine as new bacterial membrane permeabilizer agents.
Dr. Karol Ciepluch
Dr. Javier Sánchez-Nieves
Guest Editors
Manuscript Submission Information
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Keywords
- dendritic polymers
- hyperbranched polymers
- antimicrobial polymers
- nanobiotics
- bacterial membrane permeabilization
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