Smart Hydrogels in Tissue Engineering and Regenerative Medicine
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".
Deadline for manuscript submissions: closed (5 July 2022) | Viewed by 9774
Special Issue Editors
2. AMIBM-Aachen-Maastricht-Institute for Biobased Materials, Maastricht University, 186260 Geleen, The Netherlands
Interests: biohybrid and medical textiles; gas exchange membranes; pre-vascularization
Interests: elastin-like polypeptides; silk; protein polymers; bioprocessing; tissue engineering; cardiovascular implants
Special Issue Information
Dear Colleagues,
The limited capability of humans to self-heal and self-repair has been met with the development of engineered scaffolds to replace damaged tissue and organs. Of particular interest among tissue replacements are “smart hydrogels”. On one hand, the term “hydrogel” refers to the capability of a system to retain aqueous media while maintaining a defined three-dimensional structure. On the other hand, the term “smart” evokes the capability of the system to sense the environment in which it is located, and to experience changes accordingly.
A smart hydrogel intended as tissue replacement should interact with the complex environment of the human body (e.g., including parameters such as pH, temperature, biological cues), and subsequently elicit a response that can facilitate tissue restoration. In addition to the intrinsic milieu of the human body, external stimulation (e.g., electric and magnetic fields) can also be used as a tool to modulate the hydrogel performance.
The consecution of relevant “smart hydrogel”-based implants requires a deep understanding of (i) the intricate environment of the human body, and (ii) the “cross-talk” between the tissue replacement and the native tissue. An additional pivotal aspect to progress in this mission is the development of dedicated materials, able to accurately response to relevant stimuli with prospects of its application in tissue regeneration.
This Special Issue aims to highlight current progress in “smart hydrogel”-driven strategies in tissue restoration and to expand our understanding of how to modulate material–host interaction.
Prof. Dr. Stefan Jockenhoevel
Dr. Alicia Fernandez-Colino
Guest Editors
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