Oral Disorders in the Pediatric Population

A special issue of Reports (ISSN 2571-841X). This special issue belongs to the section "Dentistry/Oral Medicine".

Deadline for manuscript submissions: 28 November 2025 | Viewed by 1614

Special Issue Editors


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Guest Editor
Department of Oral Medicine and Oral Pathology, Dental School, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
Interests: oral cancer; oral precancer; salivary diseases and neoplasms; oral manifestations of systemic diseases; oral pigmentation

E-Mail Website
Guest Editor
Department of Oral Medicine and Oral Pathology, Dental School, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
Interests: oral and maxillofacial medicine; oral and maxillofacial pathology; oral and maxillofacial radiology; oral and maxillofacial surgery; periodontology; implantology

Special Issue Information

Dear Colleagues,

Oral diseases in the pediatric population represent a significant public health concern, impacting not only the immediate oral health of children but also their overall physical, emotional, and social development. The prevalence of these disorders, which include dental caries, malocclusion, periodontal diseases, and oral mucosal lesions, has been shown to vary widely across different demographic and socioeconomic groups, underscoring the need for a comprehensive understanding of their epidemiology. These disorders not only contribute to pain and discomfort but can also hinder children’s ability to eat, speak, and socialize effectively, leading to potential long-term consequences, such as poor self-esteem and academic challenges. Furthermore, the effects of oral health on systemic health, particularly in young patients with chronic conditions, highlight the intricate relationship between oral and general health, making it imperative to address these issues holistically.

The aim of this Special Issue is to underline the importance of multidisciplinary approaches, the usefulness of advanced technologies, and the importance of patient safety.

Prof. Dr. Athanasios K. Poulopoulos
Dr. Vasileios Zisis
Guest Editors

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Keywords

  • oral cancer
  • oral precancer
  • salivary diseases and neoplasms
  • oral manifestations of systemic diseases
  • oral autoimmune disorders

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Published Papers (3 papers)

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15 pages, 1583 KB  
Brief Report
Oral Health Status and Parental Awareness in Children with X-Linked Hypophosphatemic Rickets: A Case-Control Study
by Victoria Zlateva, Krasimir Hristov, Zdravka Todorova and Ralitsa Bogovska-Gigova
Reports 2025, 8(3), 151; https://doi.org/10.3390/reports8030151 - 20 Aug 2025
Viewed by 325
Abstract
X-linked hypophosphatemic rickets (XLH) is a rare genetic disorder with a frequency of 1:20,000, caused by mutations in the PHEX gene, resulting in impaired phosphate metabolism and bone mineralization. There is an association between hypophosphatemia and dental issues, though this link is not [...] Read more.
X-linked hypophosphatemic rickets (XLH) is a rare genetic disorder with a frequency of 1:20,000, caused by mutations in the PHEX gene, resulting in impaired phosphate metabolism and bone mineralization. There is an association between hypophosphatemia and dental issues, though this link is not definitively established. This study aims to evaluate the dental status, including oral hygiene, caries prevalence, and malocclusions, as well as parental awareness of dental complications, in children with XLH in Bulgaria, particularly those receiving or about to begin burosumab treatment, and to compare their oral health status with that of healthy children. Eleven children with XLH (seven girls, four boys, aged 2.5–17 years), nine receiving burosumab, were assessed and compared with eleven age- and gender-matched healthy children (seven girls, four boys, aged 2.5–17 years) without XLH or systemic conditions affecting dental health. Parental awareness of dental implications was assessed via a questionnaire, revealing no awareness of potential complications. Oral hygiene, measured using the Oral Hygiene Index-Simplified (OHI-s), was poor in 66.67% of children, with an average of 6.45 ± 5.80 carious lesions per child, and was highest in the 11–16 age group. Malocclusions were observed in 63.64% of children, and spontaneous endodontic infections occurred in 18.18%. Compared with healthy children, patients with XLH had significantly worse oral hygiene (p = 0.013) and a higher caries prevalence (p = 0.001). Children with XLH exhibit poor oral hygiene, a high caries burden, and frequent malocclusions, compounded by a lack of parental awareness of dental risks. These findings underscore the need for targeted dental interventions and education in XLH management, including the integration of routine dental assessments and structured parental education programs into existing clinical protocols to improve oral health outcomes. Full article
(This article belongs to the Special Issue Oral Disorders in the Pediatric Population)
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11 pages, 2735 KB  
Case Report
Management of a Complicated Crown Fracture in a 16-Year-Old Patient: A Case Report
by Ralitsa Bogovska-Gigova
Reports 2025, 8(3), 132; https://doi.org/10.3390/reports8030132 - 1 Aug 2025
Viewed by 451
Abstract
Background and Clinical Significance: Traumatic dental injuries, particularly complicated crown fractures of permanent incisors, are common in adolescents, with maxillary central incisors most frequently affected due to their prominent position. These injuries, often resulting from sports or accidents, require prompt management to [...] Read more.
Background and Clinical Significance: Traumatic dental injuries, particularly complicated crown fractures of permanent incisors, are common in adolescents, with maxillary central incisors most frequently affected due to their prominent position. These injuries, often resulting from sports or accidents, require prompt management to prevent complications such as pulp necrosis or infection, which can compromise long-term prognosis. Fragment reattachment offers a conservative, esthetically favorable approach when the fractured segment is intact, with outcomes comparable to composite restorations. This case report underscores the importance of timely intervention and advanced restorative techniques in pediatric dentistry. Case Presentation: A 16-year-old male presented with a complicated crown fracture of the upper left central incisor sustained during a soccer game. The fracture extended subgingivally with pulp exposure. The patient preserved the fragment in saline. Treatment involved fragment reattachment using a dentin bonding agent and flowable composite resin, followed by single-visit root canal therapy due to delayed presentation (48 h). A glass fiber post was placed to reinforce the restoration due to significant coronal loss. Three years of follow-up visits (1, 3, 6, 12, 24, and 36 months) revealed no clinical or radiographic complications, with the tooth remaining asymptomatic and functional. Conclusions: This case underscores the effectiveness of fragment reattachment when combined with meticulous technique and long-term monitoring. Full article
(This article belongs to the Special Issue Oral Disorders in the Pediatric Population)
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6 pages, 1231 KB  
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A Personalized 3D-Printed CAD/CAM Functional Space Maintainer Following the Premature Loss of a Primary First Molar in a Five-Year-Old Child
by Rasa Mladenovic, Andrija Nedeljkovic, Ljiljana Vujacic, Marko Stevanovic, Vladan Djordjevic, Srbislav Pajic and Kristina Mladenovic
Reports 2025, 8(3), 125; https://doi.org/10.3390/reports8030125 - 29 Jul 2025
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Abstract
Primary teeth play a crucial role in a child’s development, particularly in maintaining space for permanent teeth. The premature loss of a primary tooth can lead to orthodontic issues, making the use of space maintainers essential to ensure proper growth and development of [...] Read more.
Primary teeth play a crucial role in a child’s development, particularly in maintaining space for permanent teeth. The premature loss of a primary tooth can lead to orthodontic issues, making the use of space maintainers essential to ensure proper growth and development of permanent teeth. To preserve space, the fabrication of a space maintainer is necessary. Since conventional space maintainers do not restore masticatory function, this study presents an innovative solution for space preservation following the extraction of the first primary molar through the design of the functional space maintainer KOS&MET (Key Orthodontic System and Materials Enhanced Therapy). The space maintainer was designed using the 3Shape Dental Designer 2023 version software tool and manufactured via additive 3D printing, utilizing a metal alloy with high resistance to masticatory forces. The crown is supported by the primary canine, while an intraoral window is created to monitor the eruption of the successor tooth. This design does not interfere with occlusion and enables bilateral chewing. Masticatory performance was assessed using two-color chewing gum, and the results showed improvement after cementing the space maintainer. This innovative approach not only preserves space for permanent teeth but also enhances masticatory function, contributing to the proper growth and development of the jaws and teeth. Full article
(This article belongs to the Special Issue Oral Disorders in the Pediatric Population)
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