Imprinting Technology for Advanced Point-of-Care Sensing

Dear Colleagues,

Over the past few decades, imprinting technology has been extensively studied to develop rationally-designed synthetic receptors for incorporation into biomimetic sensor platforms. Various imprinting strategies have been explored, leading to the creation of selective receptors for virtually any target, varying from low molecular weight compounds such as steroids to larger macromolecular entities, such as micro-organisms or whole cells. Detection of the target rebinding is based on a large variety of readout strategies including electrochemical, piezoelectric, optical and thermal sensing approaches. With recent advances in microfabrication, signal processing, wireless transmission and microfluidics, many sensors have evolved from large laboratory scale prototypes to more elegant portable or wearable lab-on-a-chip devices. These high-tech biomimetic sensors could help to enhance advances in life science and medicine through, e.g., personalized medicine, point-of-care diagnostics or e-health. This Special Issue is devoted to publishing new and original research on the development of sensors and systems for the selective detection of medically or forensically relevant targets. We focus especially on wearable and portable sensor systems, or at least technology with the potential for miniaturization, that are preferably fast and open opportunities towards point-of-care applications. Review articles on the use of imprinting technology on point-of-care sensing of specific diseases are also highly welcome.

With kind regards,

Prof. Dr. Thomas J. Cleij
Dr. Bart van Grinsven
Dr. Kasper Eersels
Guest Editors

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