Two-Dimensional Gas Chromatography
A special issue of Separations (ISSN 2297-8739).
Deadline for manuscript submissions: closed (30 April 2016) | Viewed by 28691
Special Issue Editor
Special Issue Information
Dear Colleagues,
Over the past decade, comprehensive two-dimensional gas chromatography (GC×GC) has become a well-established and valuable technique for separating and analysing complex mixtures. GC×GC has been applied in many fields where conventional one-dimensional (1D) separations were traditionally used for volatile and semi-volatile analysis, including flavour and fragrance, environmental studies, metabolomics, pharmaceuticals, petroleum products, and forensic science. Compared to 1D GC, GC×GC provides enhanced sensitivity and superior separation power due to increased peak capacity. An additional dimension of information can be added by employing detection systems such as time-of-flight mass spectrometers (TOFMS). The ongoing evolution of GC×GC has included advances in modulation, data handling and application development. Improved quantitative data analysis is necessary to move the use of GC×GC from research laboratories to more widespread use in commercial laboratories. Discussion at recent scientific meetings has focused on reaching a near-theoretical peak capacity and the implementation of high resolution TOFMS. This Special Issue invites contributions that highlight the latest research and advancements in GC×GC technology, and demonstrate the range of applications and fields for which its use is particularly beneficial.
Prof. Dr. Shari Forbes
Guest Editor
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Keywords
- multidimensional chromatography
- GC×GC
- HRTOFMS
- complex mixture characterisation
- non-targeted analysis
- chemometrics
- data handling strategies/software
- chromatographic alignment
- peak capacity
- biomarker discovery
- application development
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