Innovations in Immunotherapy: Advancements in Cancer Vaccines and Immune Modulation
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Cancer Vaccines and Immunotherapy".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 101
Special Issue Editors
Interests: tumor immunology; pan-cancer; machine learning
Special Issues, Collections and Topics in MDPI journals
Interests: oncology; immunology; glioma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advancements in cancer vaccines aim to educate the immune system to recognize and destroy cancer cells, offering the potential for long-lasting protection against recurrence. Additionally, using model organisms has proven invaluable for discovering and validating immunotherapeutic strategies, enabling researchers to explore novel immune-modulating agents. Multi-omics approaches, integrating genomics, transcriptomics, proteomics, and metabolomics, have become essential in elucidating the complex interactions within tumors and their microenvironments. These comprehensive analyses are crucial for identifying new biomarkers and therapeutic targets, ultimately guiding the development of personalized immunotherapy regimens. Cancer vaccine technologies are still in development, and various formats have been explored in preclinical and clinical studies for off-the-shelf and personalized cancer vaccines. Cancer vaccines face a significant challenge. Shared antigen cancer vaccines can be mass-produced as ready-to-use, reducing production times and costs. In contrast, personalized neoantigen vaccines are treated as a stand-alone drug, demanding rapid drug production, scalability, and cost control needed to enable rapid clinical application. Adopting a synthetic vaccine technology that facilitates fast and cost-effective production is essential to address vaccine complexities. This Special Issue will focus on the advancement of cancer vaccines concentrated in several key areas including identifying immunogenic neoantigens, optimizing vectors and delivery platforms, and using multi-omics and precision medicine in cancer vaccine development.
Dr. Nan Zhang
Dr. Hao Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- multi-omics
- cancer therapy
- precision medicine
- cancer vaccines
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