Zebrafish Neural Development in Toxicological Studies
A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Anatomy, Histology and Pathology".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 701
Special Issue Editors
Interests: animal anatomy; animal welfare; functional morphology; neuronal development; oxidative stress; sustainable animal production; zebrafish
Special Issues, Collections and Topics in MDPI journals
Interests: toxicology; zebrafish; oxidative stress; biochemistry; behavior; development; mitochondria; ecotoxicology
Special Issues, Collections and Topics in MDPI journals
Interests: toxicity studies; ecotoxicology, biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development of the central nervous system is a complex process dependent on genetic and molecular mechanisms that coordinate cells from proliferation to tissue organization. The key features of these mechanisms are phylogenetically conserved. Over the years, animal models have been widely used to study the neurotoxicological impact of different compounds. In addition to rodents, the zebrafish has gained popularity as a translational animal model. In particular, the zebrafish embryo transparency, fast brain development, and its organizational homology with higher vertebrates are important advantages to in vivo studies. Recent research has highlighted the need for a comprehensive neurotoxicity assessment for different compounds, to avoid risks to the environment or animal/human health/welfare. This can be based on the reactive oxygen species, gene expression patterns, cell death, neural morphogenesis and behavioural endpoints.
Therefore, we are pleased to invite all experts in the field of developmental neurotoxicity who work with zebrafish to contribute to this Special Issue of Veterinary Sciences with original research or review articles.
The contributions should be focused on the use of zebrafish, as a neural development model, for screening the safety of environmental compounds or others used in animals and humans, contributing with important information for the One Health and One Welfare approach.
Dr. Carlos Alberto e Silva Venâncio
Dr. Luís Félix
Dr. Sandra Mariza Monteiro
Guest Editors
Manuscript Submission Information
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Keywords
- animal model
- behavioural
- brain development
- cell death
- compounds screening
- morphogenesis
- neurotoxicity
- one health
- oxidative stress
- zebrafish
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