Advances in Alphavirus and Flavivirus Research, 2nd Edition

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 937

Special Issue Editors


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Guest Editor
Department of Paediatrics, University of Oxford, Headington, Oxford OX3 9DU, UK
Interests: alphaviruses; flaviviruses: Chagas; bacteria; vaccines; diagnostics; immunology; immunoassays
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. The Jenner Institute, ORCRB, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK
2. Instituto Politécnico Nacional, IPN. Av. Luis Enrique Erro s/n. Unidad Adolfo López Mateos, Mexico City, Mexico
Interests: plasmodium vivax; pre-erythrocytic malaria vaccines; flavivirus vaccines; alphavirus-based vaccines; zika vaccines; dengue vaccines; chikungunya vaccines; VLP; recombinant viral vectors; chimpanzee adenovirus (ChAdOx); MVA
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue, Advances in Alphavirus and Flavivirus Research (https://www.mdpi.com/journal/viruses/special_issues/alphavirus_flavivirus_research).

As we have seen during the last decade and the most recent pandemics, the emergence or re-emergence of zoonotic viral diseases has become one of the most important public health concerns globally. In particular, mosquito-borne viruses such as Dengue (DENV), Zika (ZIKV), and Chikungunya (CHIKV) viruses have emerged in recent decades, affecting millions of people worldwide. These alphaviruses and flaviviruses can be classified into a broader category of arboviruses, and they cause significant disease burdens and public health concerns. This Special Issue entitled “Advances in Alphavirus and Flavivirus Research” is devoted to publishing advances made in alphavirus and flavivirus research.

We welcome the submission of all types of articles, including short reports, original research, and reviews, for this Special Issue. We look forward to receiving your contributions.

Dr. Young Chan Kim
Dr. Arturo Reyes-Sandoval
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • arbovirus
  • alphavirus
  • flavivirus
  • Chikungunya
  • Mayaro
  • Zika
  • dengue
  • diagnostics
  • surveillance
  • vaccine
  • antivirals
  • animal models

Published Papers (1 paper)

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Research

16 pages, 2174 KiB  
Article
Elucidation of the Epitranscriptomic RNA Modification Landscape of Chikungunya Virus
by Belinda Baquero-Pérez, Enrico Bortoletto, Umberto Rosani, Anna Delgado-Tejedor, Rebeca Medina, Eva Maria Novoa, Paola Venier and Juana Díez
Viruses 2024, 16(6), 945; https://doi.org/10.3390/v16060945 - 12 Jun 2024
Viewed by 745
Abstract
The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral [...] Read more.
The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral RNA modification in infected human cells. Among the 32 distinct RNA modifications analysed by mass spectrometry, inosine was found enriched in the genomic CHIKV RNA. However, orthogonal validation by Illumina RNA-seq analyses did not identify any inosine modification along the CHIKV RNA genome. Moreover, CHIKV infection did not alter the expression of ADAR1 isoforms, the enzymes that catalyse the adenosine to inosine conversion. Together, this study highlights the importance of a multidisciplinary approach to assess the presence of RNA modifications in viral RNA genomes. Full article
(This article belongs to the Special Issue Advances in Alphavirus and Flavivirus Research, 2nd Edition)
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