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30 Results Found

  • Article
  • Open Access
2 Citations
2,330 Views
21 Pages

29 July 2023

For more than a decade, researchers and practitioners have been working to advance the implementation of virtual design and construction (VDC) and building information modeling (BIM) in the construction industry. Based on the product-organization-pro...

  • Article
  • Open Access
14 Citations
5,858 Views
15 Pages

Modifying a Paediatric Rational Prescribing Tool (POPI) for Use in the UK

  • Fenella Corrick,
  • Imti Choonara,
  • Sharon Conroy and
  • Helen Sammons

20 February 2019

Rational prescribing tools can be used by individual prescribers, organisations, and researchers to evaluate the quality of prescribing for research and quality improvement purposes. A literature search showed that there is only one tool for evaluati...

  • Article
  • Open Access
3 Citations
4,102 Views
19 Pages

Maximum Electrical Power Extraction from Sources by Load Matching

  • Sigmund Singer,
  • Shlomi Efrati,
  • Meir Alon and
  • Doron Shmilovitz

1 December 2021

This paper describes the matching of various loads to sources (including nonlinear ones). The purpose of matching is to extract the maximum available power from the source. This has particular importance for renewable sources and energy-harvesting de...

  • Article
  • Open Access
5 Citations
2,010 Views
14 Pages

26 November 2024

The protein transition motivates the use of plant proteins, but their application in food emulsions is challenging, especially when high concentrations of oil and salt are needed for formulation and sensory properties. In the present work, we connect...

  • Review
  • Open Access
13 Citations
5,041 Views
13 Pages

Paediatric Rational Prescribing: A Systematic Review of Assessment Tools

  • Fenella Corrick,
  • Sharon Conroy,
  • Helen Sammons and
  • Imti Choonara

Rational prescribing criteria have been well established in adult medicine for both research and quality improvement in the appropriate use of medicines. Paediatric rational prescribing has not been as widely investigated. The aims of this review wer...

  • Article
  • Open Access
50 Citations
8,952 Views
22 Pages

6 November 2020

Understanding the spatial distribution of populations at a finer spatial scale has important value for many applications, such as disaster risk rescue operations, business decision-making, and regional planning. In this study, a random forest (RF)-ba...

  • Article
  • Open Access
31 Citations
6,430 Views
11 Pages

Recent meta-analyses of positive organizational psychology interventions (POPIs) suggest that interventions that target and improve hope, efficacy, resilience, and optimism (HERO) can be highly effective at improving well-being and positive functioni...

  • Article
  • Open Access
11 Citations
5,879 Views
34 Pages

Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients

  • Aikaterini F. Giannopoulou,
  • Eumorphia G. Konstantakou,
  • Athanassios D. Velentzas,
  • Socratis N. Avgeris,
  • Margaritis Avgeris,
  • Nikos C. Papandreou,
  • Ilianna Zoi,
  • Vicky Filippa,
  • Stamatia Katarachia and
  • Dimitrios J. Stravopodis
  • + 12 authors

21 February 2019

Background: Skin cancer represents the most common human malignancy, and it includes BCC, SCC, and melanoma. Since melanoma is one of the most aggressive types of cancer, we have herein attempted to develop a gene-specific intron retention signature...

  • Article
  • Open Access
2 Citations
3,246 Views
20 Pages

Selective Destabilization of Transcripts by mRNA Decapping Regulates Oocyte Maturation and Innate Immunity Gene Expression during Ageing in C. elegans

  • Fivos Borbolis,
  • Dimitra Ranti,
  • Maria-Despina Papadopoulou,
  • Sofia Dimopoulou,
  • Apostolos Malatras,
  • Ioannis Michalopoulos and
  • Popi Syntichaki

21 January 2023

Removal of the 5′ cap structure of RNAs (termed decapping) is a pivotal event in the life of cytoplasmic mRNAs mainly catalyzed by a conserved holoenzyme, composed of the catalytic subunit DCP2 and its essential cofactor DCP1. While decapping w...

  • Review
  • Open Access
13 Citations
7,131 Views
26 Pages

The Yin/Yang Balance of Communication between Sensory Neurons and Macrophages in Traumatic Peripheral Neuropathic Pain

  • Roxana-Olimpia Gheorghe,
  • Andreea Violeta Grosu,
  • Melania Bica-Popi and
  • Violeta Ristoiu

16 October 2022

Traumatic peripheral neuropathic pain is a complex syndrome caused by a primary lesion or dysfunction of the peripheral nervous system. Secondary to the lesion, resident or infiltrating macrophages proliferate and initiate a cross-talk with the senso...

  • Review
  • Open Access
13 Citations
4,222 Views
17 Pages

B-cell development is a very orchestrated pathway that involves several molecules, such as transcription factors, cytokines, microRNAs, and also different cells. All these components maintain the ideal microenvironment and control B-cell differentiat...

  • Review
  • Open Access
16 Citations
4,880 Views
20 Pages

Potential Cell-Based and Cell-Free Therapy for Patients with COVID-19

  • Marselina Irasonia Tan,
  • Nayla Majeda Alfarafisa,
  • Popi Septiani,
  • Anggraini Barlian,
  • Mochamad Firmansyah,
  • Ahmad Faizal,
  • Lili Melani and
  • Husna Nugrahapraja

27 July 2022

Since it was first reported, the novel coronavirus disease 2019 (COVID-19) remains an unresolved puzzle for biomedical researchers in different fields. Various treatments, drugs, and interventions were explored as treatments for COVID. Nevertheless,...

  • Article
  • Open Access
3 Citations
3,083 Views
15 Pages

Associations between Body Composition and Vitamin D Status in Children with Overweight and Obesity Participating in a 1-Year Lifestyle Intervention

  • Popi Kasvis,
  • Tamara R. Cohen,
  • Sarah-Ève Loiselle,
  • Tom J. Hazell,
  • Catherine A. Vanstone and
  • Hope A. Weiler

30 July 2022

Background: To examine associations between body composition and vitamin D status in children participating in a lifestyle intervention. Methods: Children (6–12 y, n = 101) with a body mass index (BMI)-for-age >85th percentile were randomize...

  • Review
  • Open Access
24 Citations
6,971 Views
24 Pages

Optimising Water Management in Drylands to Increase Crop Productivity and Anticipate Climate Change in Indonesia

  • Popi Rejekiningrum,
  • Yayan Apriyana,
  • Sutardi,
  • Woro Estiningtyas,
  • Hendri Sosiawan,
  • Helena Lina Susilawati,
  • Anggri Hervani and
  • Annisa Dhienar Alifia

16 September 2022

In the future, Indonesia will become increasingly dependent on dryland agriculture. New adaptive technology innovations able to transform drylands into arable land throughout almost the entire year have been developed to anticipate global climate cha...

  • Article
  • Open Access
869 Views
15 Pages

5 November 2025

Background/Objectives: The growing intersection between nyaope use and HIV infection constitutes a critical public health problem that undermines efforts to achieve universal access to HIV treatment in South Africa. Nyaope use is strongly associated...

  • Article
  • Open Access
7 Citations
5,257 Views
51 Pages

From Proteomic Mapping to Invasion-Metastasis-Cascade Systemic Biomarkering and Targeted Drugging of Mutant BRAF-Dependent Human Cutaneous Melanomagenesis

  • Aikaterini F. Giannopoulou,
  • Athanassios D. Velentzas,
  • Athanasios K. Anagnostopoulos,
  • Adamantia Agalou,
  • Nikos C. Papandreou,
  • Stamatia A. Katarachia,
  • Dimitra G. Koumoundourou,
  • Eumorphia G. Konstantakou,
  • Vasiliki I. Pantazopoulou and
  • Dimitrios J. Stravopodis
  • + 14 authors

22 April 2021

Melanoma is classified among the most notoriously aggressive human cancers. Despite the recent progress, due to its propensity for metastasis and resistance to therapy, novel biomarkers and oncogenic molecular drivers need to be promptly identified f...

  • Article
  • Open Access
20 Citations
6,084 Views
27 Pages

Organismal and Cellular Stress Responses upon Disruption of Mitochondrial Lonp1 Protease

  • Eirini Taouktsi,
  • Eleni Kyriakou,
  • Stefanos Smyrniotis,
  • Fivos Borbolis,
  • Labrina Bondi,
  • Socratis Avgeris,
  • Efstathios Trigazis,
  • Stamatis Rigas,
  • Gerassimos E. Voutsinas and
  • Popi Syntichaki

16 April 2022

Cells engage complex surveillance mechanisms to maintain mitochondrial function and protein homeostasis. LonP1 protease is a key component of mitochondrial quality control and has been implicated in human malignancies and other pathological disorders...

  • Proceeding Paper
  • Open Access
14 Citations
4,783 Views
8 Pages

Energy Benchmarking and Optimization of Wastewater Treatment Plants in Greece

  • Popi Christoforidou,
  • George Bariamis,
  • Maria Iosifidou,
  • Eri Nikolaidou and
  • Petros Samaras

Wastewater treatment, as a crucial component of the urban water environment, consists of several energy-consumptive stages, therefore efficiency and energy savings measures are essential to maintain them as environmentally sustainable and economicall...

  • Article
  • Open Access
4 Citations
2,911 Views
17 Pages

Mitochondrial p38 Mitogen-Activated Protein Kinase: Insights into Its Regulation of and Role in LONP1-Deficient Nematodes

  • Eirini Taouktsi,
  • Eleni Kyriakou,
  • Evangelia Voulgaraki,
  • Dimitris Verganelakis,
  • Stefania Krokou,
  • Stamatis Rigas,
  • Gerassimos E. Voutsinas and
  • Popi Syntichaki

7 December 2023

p38 Mitogen-Activated Protein Kinase (MAPK) cascades are central regulators of numerous physiological cellular processes, including stress response signaling. In C. elegans, mitochondrial dysfunction activates a PMK-3/p38 MAPK signaling pathway (MAPK...

  • Article
  • Open Access
8 Citations
3,845 Views
18 Pages

Analysis of Climate Change Impacts on Agricultural Water Availability in Cimanuk Watershed, Indonesia

  • Nani Heryani,
  • Budi Kartiwa,
  • Hendri Sosiawan,
  • Popi Rejekiningrum,
  • Setyono Hari Adi,
  • Yayan Apriyana,
  • Aris Pramudia,
  • Muhammad Prama Yufdy,
  • Chendy Tafakresnanto and
  • Cahyati Setiani
  • + 5 authors

5 December 2022

Climate change has been affecting agricultural water resources dynamics spatially and temporally. This article presents analysis results of climate change impact on agricultural water availability in Cimanuk Watershed, Indonesia. STREAM was utilized...

  • Review
  • Open Access
43 Citations
16,577 Views
14 Pages

The Transformation of Rice Crop Technology in Indonesia: Innovation and Sustainable Food Security

  • Sutardi,
  • Yayan Apriyana,
  • Popi Rejekiningrum,
  • Annisa Dhienar Alifia,
  • Fadhlullah Ramadhani,
  • Valeriana Darwis,
  • Nanik Setyowati,
  • Dwi Eny Djoko Setyono,
  • Gunawan and
  • Andi Yulyani Fadwiwati
  • + 7 authors

20 December 2022

The growth of the Indonesian population has led to an increase in the demand for rice, which the country has yet to satisfy. Indonesia needs a comprehensive strategy that integrates meaningful efforts to increase its agricultural production. This stu...

  • Article
  • Open Access
9 Citations
3,313 Views
16 Pages

The Effect of P2O5 Fertilizer, Zeolite, and Volcanic Soil Media from Different Altitudes on the Soil Mineral, Growth, Yield, and Asiaticoside Content of Centella asiatica L.

  • Damasus Riyanto,
  • Meksy Dianawati,
  • Sutardi,
  • Heru Susanto,
  • Nugroho Adi Sasongko,
  • Niluh Putu Sri Ratmini,
  • Popi Rejekiningrum,
  • Yustisia,
  • Helena Lina Susilawati and
  • Tri Martini
  • + 6 authors

19 November 2022

Centella asiatica is an herbal plant with many health benefits due to the content of asiaticoside compounds. Factors affecting asiaticoside content are altitude, soil texture, and soil nutrient status. This research aimed to identify the effect of ze...

  • Review
  • Open Access
18 Citations
5,023 Views
18 Pages

The Thermal Stress Coping Network of the Nematode Caenorhabditis elegans

  • Eleni Kyriakou,
  • Eirini Taouktsi and
  • Popi Syntichaki

28 November 2022

Response to hyperthermia, highly conserved from bacteria to humans, involves transcriptional upregulation of genes involved in battling the cytotoxicity caused by misfolded and denatured proteins, with the aim of proteostasis restoration. C. elegans...

  • Review
  • Open Access
1 Citations
1,749 Views
19 Pages

Effects of Ultra-Processed Foods and Food Additives on Disease Activity in Adults with Inflammatory Bowel Disease: A Scoping Review

  • Andrea Soublette Figuera,
  • Sara Alessa,
  • Carolyne Brien,
  • Mary Hendrickson,
  • Popi Kasvis and
  • Talat Bessissow

3 November 2025

Background/Objectives: This scoping review aims to identify and map out the current state of research on the relationship between ultra-processed foods (UPF) intake and disease activity and symptoms in adults with inflammatory bowel disease (IBD). Me...

  • Proceeding Paper
  • Open Access
538 Views
8 Pages

Bending Behavior of the 95% and 99% Alumina Ceramics

  • Sergiu-Valentin Galatanu,
  • Victor Tiberiu Popi,
  • Cosmin-Florin Popa and
  • Liviu Marsavina

30 December 2025

Alumina ceramics, known for their hardness, thermal resistance, and chemical stability, are widely applied in engineering and industry. This study investigates the flexural strength of 95% and 99% alumina ceramics using tubes with two or four cross-s...

  • Article
  • Open Access
2 Citations
2,362 Views
19 Pages

15 May 2023

Diaryl-furanones are specific analytical reagents for the biochemical detection of primary amines by fluorescence techniques. Well-known reagents are fluorescamine (Fluram) and 2-methoxy-2,4-diphenyl-3(2H)-furanone (MDPF), yielding fluorescent produc...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,922 Views
14 Pages

5 January 2021

One of the central elements in systems biology is the interaction between mathematical modeling and measured quantities. Typically, biological phenomena are represented as dynamical systems, and they are further analyzed and comprehended by identifyi...

  • Article
  • Open Access
3 Citations
2,581 Views
11 Pages

A Snapshot of Potentially Inappropriate Prescriptions upon Pediatric Discharge in Oman

  • Alaa M. Soliman,
  • Ibrahim Al-Zakwani,
  • Ibrahim H. Younos,
  • Shireen Al Zadjali and
  • Mohammed Al Za’abi

23 September 2022

Background: Identifying and quantifying potentially inappropriate prescribing (PIP) practices remains a time-consuming and challenging task, particularly among the pediatric population. In recent years, several valuable tools have been developed and...

  • Article
  • Open Access
4 Citations
2,914 Views
16 Pages

Soil Phosphorus Forms in Saline Soil after the Application of Biomass Materials

  • Xuewei Guan,
  • Jinlin Chen,
  • Guangming Liu and
  • Xiuping Wang

25 January 2024

Although the application of biological materials has shown potential in improving the environment of salinized soil, the impact on the transformation of soil phosphorus forms in salinized soil, especially when combined with B. mucilaginosus (BM)...

  • Article
  • Open Access
15 Citations
4,911 Views
15 Pages

Selection of Parental Material to Maximize Heterosis Using SNP and SilicoDarT Markers in Maize

  • Agnieszka Tomkowiak,
  • Jan Bocianowski,
  • Dominika Radzikowska and
  • Przemysław Łukasz Kowalczewski

14 September 2019

The chief aim of plant breeding is to improve varieties so as to increase their yield and breeding traits. One of the first stages of breeding is the selection of parental forms from the available gene pool of existing varieties. To date, costly and...