Search Results (746)

The search for more sustainable alternatives to traditional organic solvents, in the frame of the green chemistry approach, is leading to an increasing interest toward the exploration of deep eutectic solvents (DESs), especially natural-based ones (NADESs). The great ferment in the use of DESs as innovative media for many applications and in the research of novel types of DESs is not matched by an equal rigor in their characterization and in the study of their physico-chemical characteristics. Nevertheless, it is evident how comparative studies encompassing the investigation of a wide range of properties in relationship with the DESs structures would be beneficial for a rational development of the field. In this work a panel of DESs featuring choline acetate, L-carnitine and L-proline as hydrogen bond acceptor constituents (HBAs) and ethylene glycol, glycerol and levulinic acid as hydrogen bond donor constituents (HBDs) in 1:2 and 1:3 molar ratios have been prepared and characterized. Their density, viscosity and optical properties have been thoroughly investigated at various temperatures, analyzing the influence of their composition in terms of type of HBA, type of HBD and molar ratio on their properties. All the proposed DESs have also been thermally characterized by TGA and DSC, providing a description of their thermal behavior in a wide range of temperature and determining their thermal stability and thermal degradation profile. Full article

Background/Objectives: Workplace conflict and aggression pose significant psychosocial risks across diverse professional sectors. This protocol outlines a novel, university-based educational intervention. Developed by a multidisciplinary team from the University Hospital of Pisa, Italy, including occupational physicians and a psychiatrist specializing in work and organizational psychology, its primary purpose is to enhance conflict prevention and crisis management skills. While initially developed and tested within the veterinary sector due to its identified vulnerabilities, the intervention is inherently generalizable to any high-stress professional environment characterized by intense client, customer, or public interactions. Methods: The intervention integrates didactic instruction with active, immersive learning through tailored role-playing scenarios simulating real-world challenging encounters. This study protocol details the structured methodology for evaluating the immediate effectiveness of this training. We are using a specifically developed efficacy scale to assess outcomes. Results: The results demonstrate a significant improvement in all assessed skills from the pre-training to the post-training evaluation. For every item on the scale, the median scores increased, indicating a positive shift in overall group performance. The p-value for each item was <0.001, confirming that the observed improvements were statistically significant. These results demonstrate enhanced conflict resolution skills, improved communication, and an increased sense of self-efficacy among participants. Conclusions: This protocol offers a comprehensive and generalizable approach to addressing workplace psychosocial risks through an innovative educational intervention. A key future goal involves advancing this training methodology by integrating virtual reality (VR) environments with AI-driven avatars for role-playing, aiming to achieve a more realistic and impactful learning experience and sustained behavioral change. Full article

Alzheimer’s disease is a growing global health concern, demanding innovative solutions for early detection, continuous monitoring, and patient support. This article reviews recent advances in Smart Wearable Medical Devices (SWMDs), Internet of Things (IoT) systems, and mobile applications used to monitor physiological, behavioral, and cognitive changes in Alzheimer’s patients. We highlight the role of wearable sensors in detecting vital signs, falls, and geolocation data, alongside IoT architectures that enable real-time alerts and remote caregiver access. Building on these technologies, we present LumiCare, a conceptual, context-aware mobile system that integrates multimodal sensor data, chatbot-based interaction, and emerging 6G network capabilities. LumiCare uses machine learning for behavioral analysis, delivers personalized cognitive prompts, and enables emergency response through adaptive alerts and caregiver notifications. The system includes the LumiCare Companion, an interactive mobile app designed to support daily routines, cognitive engagement, and safety monitoring. By combining local AI processing with scalable edge-cloud architectures, LumiCare balances latency, privacy, and computational load. While promising, this work remains at the design stage and has not yet undergone clinical validation. Our analysis underscores the potential of wearable, IoT, and mobile technologies to improve the quality of life for Alzheimer’s patients, support caregivers, and reduce healthcare burdens. Full article

This study investigates the impact of employee well-being, work flexibility, and innovative work behavior on job performance among full-time and gig workers in digital businesses. A comparative analysis was conducted to examine potential differences between the two groups. A structured questionnaire was administered to 201 full-time employees in digital business system development and 199 gig workers from the IT Support Thailand group on Facebook using convenience sampling. The data were analyzed using multiple group structural equation modeling (MG-SEM) via partial least squares (PLS). The findings reveal that work flexibility boosts innovative work behavior, with gig workers showing greater adaptability than full-time employees. Innovative work behavior is positively linked to job performance, underscoring creativity’s role in organizational success. However, employee well-being and work flexibility did not demonstrate a significant direct effect on job performance. This study employed a sample of full-time and gig workers in Thai digital businesses, which may limit the generalizability of our findings to other industries or sectors. To enhance external validity, future research is recommended, including comparative studies across diverse employment forms and industries. Moreover, the adoption of a mixed-methods approach is encouraged to provide a more comprehensive understanding and broaden the scope of inquiry across multiple national contexts. Our findings underscore the need for policies that promote flexibility, well-being, and innovation to boost job performance. Digital business managers should foster adaptability, creativity, and support for both full-time and gig workers. An inclusive, balanced work environment can enhance performance, innovation, and satisfaction, helping organizations stay competitive in fast-changing markets. This study contributes to digital business research by examining the interplay between employee well-being, work flexibility, and innovative work behavior in determining job performance across different employment types. Full article

Geopolymers represent an innovative and environmentally sustainable alternative to traditional construction materials, offering significant potential for reducing anthropogenic CO₂ emissions. Among these, phosphoric acid-activated metakaolin-based systems have attracted increasing attention for their chemical and thermal resilience. In this study, we present a comprehensive structural and mechanical evaluation of metakaolin-based geopolymers synthesized across a wide range of Al/P molar ratios (0.8–4.0). Six formulations were systematically prepared and analyzed using X-ray powder diffraction (XRPD), small-angle X-ray scattering (SAXS), Fourier-transform infrared spectroscopy (FTIR), solid-state nuclear magnetic resonance (ssNMR), and complementary mechanical testing. The novelty of this work lies in the integrated mapping of composition–structure–property relationships across the broad Al/P spectrum under controlled synthesis, combined with the rare application of SAXS to reveal composition-dependent nanoscale domains (~18–50 nm). We identify a stoichiometric window at Al/P ≈ 1.5, where complete acid consumption leads to a structurally homogeneous AlVI–O–P network, yielding the highest compressive strength. In contrast, acid-rich systems exhibit divergent flexural and compressive behaviors, with enhanced flexural strength linked to hydrated silica domains arising from metakaolin dealumination, quantitatively tracked by ²⁹Si MAS NMR. XRPD further reveals the formation of uncommon Si–P crystalline phases (SiP₂O₇, Si₅P₆O₂₅) under low-temperature curing in acid-rich compositions. Together, these findings provide new insights into the nanoscale structuring, phase evolution, and stoichiometric control of silica–alumino–phosphate geopolymers, highlighting strategies for optimizing their performance in demanding thermal and chemical environments. Full article

In the race toward next-generation electronics and energy systems, ceramic nanocomposites have taken center stage due to their remarkable dielectric and ferroelectric functionalities. By pushing the boundaries of nanoscale engineering, recent studies have shown how microstructural control and interfacial design can unlock unprecedented levels of polarization, permittivity, and frequency stability. This review presents a critical and up-to-date synthesis of the last decade’s progress in ceramic-based nanocomposites, with a special focus on the structure property processing nexus. Diverse processing techniques ranging from conventional sintering to advanced spark plasma sintering and scalable wet-chemical methods are analyzed for their influence on phase purity, grain boundary behavior, and interfacial polarization. The review also explores breakthroughs in lead-free and eco-friendly systems, flexible ferroelectric nanocomposites, and high-k dielectrics suitable for miniaturized devices. By identifying both the scientific opportunities and persistent challenges in this rapidly evolving field, this work aims to guide future innovations in material design, device integration, and sustainable performance. Full article

Corporate team unity and role clarity are crucial for organizational success and human resources. This study examines how job clarity affects employee performance and innovative work behavior (IWB) via organizational citizenship behavior (OCB). Additionally, to determine how artificial intelligence (AI) information and leader-member exchange (LMX) moderate the relationship between job clarity, IWB, and employee performance. This research focused on Pakistan’s Federal Capital Territory (FCT) Islamabad, and Punjab province’s IT sectors. The self-administered questionnaire received data from 555 IT professionals. The suggested model was tested using Smart PLS structural equation modeling. Results showed that job clarity and OCB significantly improve IWB and employee performance. Role clarity, IWB, and employee performance are partly mediated by OCB. In addition, LMX adversely moderates the relationship between job clarity and IWB and employee performance, but not AI information. Emphasis is primarily placed on elucidating the respective roles of the employees in order to ensure that they are aware of the expectations placed upon them. Consequently, they are able to demonstrate task performances that are not stipulated in their job descriptions but directly relate to their performance improvement. The current study reveals that human resources (HR) and management should prioritize job clarity and OCB to boost individual performance and IWB. Full article

Building Information Modeling (BIM) is an innovative and effective solution to transform the Architecture, Engineering, and Construction (AEC) sector, offering advantages that extend across the entire lifecycle of project management. Nonetheless, several obstacles hinder the comprehensive implementation of BIM. As a result of these obstacles, construction enterprises opt to delegate the development and utilization of BIM models to specialized outsourcing providers that focus on BIM services. Since limited research focused on examining the formation mechanisms behind BIM outsourcing process, this paper elucidates the mechanisms that underpin BIM outsourcing behavior by applying Ajzen’s theory of planned behavior (TPB) and integrating transition costs along with institutional pressures theory. The behavioral model underwent empirical validation through the application of partial least squares structural equation modeling (PLS-SEM) on survey data collected from construction engineers working for construction enterprises in China. The results indicated that (1) BIM outsourcing degree is motivated by an organization’s BIM outsourcing intention and BIM application capability; (2) behavioral attitudes, especially external production cost advantage, contributes the most toward achieving a high BIM outsourcing intention, followed by normative pressures; (3) transition cost contributes the most toward achieving a low BIM outsourcing intention. This research expands the theoretical framework of the TPB and provides insight into BIM outsourcing behavior in construction enterprises. Full article

This work establishes the first derivation of geometry-dependent Kirchhoff’s laws via conformal symmetry, enabling new types of self-sustaining circuits unattainable in classical lumped-element theory. Building on Bessel-Hagen’s extension of Noether’s theorem to Maxwell’s equations, we develop a conformal circuit formalism that fundamentally extends traditional circuit theory through two key innovations: (1) Geometry-dependent weighting factors ($w_i\propto a_i^{-1}$) in Kirchhoff’s laws derived from scaling symmetry; (2) A dilaton-like field ($\delta$) mediating energy exchange between circuits and conformal backgrounds. Unlike prior symmetry applications in electromagnetism, our approach directly maps the 15-parameter conformal group to component-level circuit transformations, predicting experimentally verifiable phenomena: (i) $10.2\%$ deviations from classical current division in RF splitters; (ii) $4.2\%$ resonant frequency shifts with $2.67\times$ Q-factor enhancement; (iii) Power-law scaling ($J_z\propto a^{-2}$) in cylindrical conductors. This theoretical framework proposes how conformal symmetry could enable novel circuit behaviors, including potential self-sustaining oscillations, subject to experimental validation. Full article

Sierra Leone possesses distinct educational, economic, and social characteristics. Public universities in the country, funded by the government, are mandated to promote sustainable development, ethical conduct, and social welfare, aligning with national development strategies such as the Midterm National Development Plan and the Education Sector Plan, which emphasize leadership, diversity, and ethical standards to advance sustainable development practices. This study applies Transformational Leadership Theory to investigate the influence of transformational leadership on corporate social responsibility, exploring the mediating role of innovative work behavior and the moderating effect of organizational culture on this relationship. Using a stratified sampling technique, data were collected from 367 employees across six public universities in Sierra Leone and analyzed with SMART PLS software 4.1.1.2. The findings revealed that transformational leadership positively and significantly impacts corporate social responsibility and innovative work behavior, with innovative work behavior partially mediating the relationship between transformational leadership and corporate social responsibility, while organizational culture positively and significantly moderates this relationship. Based on these findings, the study recommends that public universities in Sierra Leone integrate transformational leadership principles into their institutional frameworks to improve organizational outcomes and leadership effectiveness. This can be achieved through leadership development programs emphasizing transformational attributes such as inspirational motivation, individualized consideration, and vision-sharing, alongside mentorship programs for leaders at all levels to strengthen leadership skills and foster an organizational culture aligned with institutional goals. Full article

This review analyzes the Electronic Digital Twin (EDT) tools characterizing the industrial transformation phase from Industry 4.0 to Industry 5.0. The goal is to provide innovative research EDT solutions to integrate in manufacturing production processes. Specifically, this research is focused on the possibility of combining the advanced technologies and electronics and mechatronics of industrial machines with Artificial Intelligence (AI) algorithms. Furthermore, this review provides important elements about possible future implementations of AI-EDTs and some circuital examples to support the understanding of the concept of circuit simulation in EDT models. EDTs are useful to comprehend the modeling concepts functional to the AI application using the output of the circuit simulations. The output of the circuit is used to train the AI model, thus strengthening the capability to classify and predict the real behavior of production machines with a good accuracy. This review discusses perspectives, limits, and advantages of EDTs and is useful to define new research patterns integrating structured EDTs in advanced industrial environments. The focus of this paper is the definition of possible perspectives of EDT implementations, including AI, in data-driven processes in specific strategic areas of industrial research by classifying the scientific topics in six main pillars. This paper is also suitable for the researcher to develop innovative topics for projects scaled into different work packages based on EDT facilities. Full article

Municipal sewage treatment plants generate significant amounts of polluting sludge, which demands innovative valorization approaches to support its sustainable recycling. This work aimed to evaluate the valorization potential of sludge from a municipal sewage treatment plant (STP) as an alternative raw material to traditional limestone in red wall tile formulations. For this purpose, four red wall tile formulations were performed with 0%, 5%, 10%, and 15% weight of STP sludge replacing traditional limestone. The tile formulations prepared by the dry process were characterized to determine their chemical and mineral compositions, thermal analysis, and sintering behavior. The red wall tile pieces were manufactured by pressing and firing at temperatures ranging from 1150 °C to 1180 °C. The effects of STP sludge incorporation and firing temperature on the densification behavior and technological properties were investigated. The results indicated that the STP sludge exhibited good chemical compatibility for use in red wall tile formulations. Water absorption values varied between 16.52% and 19.70%, indicating compliance with the red wall tile production (BIII group). These findings demonstrate the valorization potential of STP sludge in red wall tiles, which offers a relevant recycling option for the sanitation sector and the circular economy. Full article

Therapeutic resistance remains a critical barrier in effective cancer treatment, contributing to disease recurrence, progression, and reduced patient survival. In recent years, natural bioactive compounds have emerged as promising adjuncts in oncology due to their ability to modulate multiple biological processes involved in resistance. This review explores current evidence on the role of natural compounds in influencing cancer cell behavior and their interactions with the tumor microenvironment. By organizing these compounds into chemical families, we provide a structured overview of their potential to enhance the efficacy of standard chemotherapy and reduce resistance-related mechanisms. We also highlight innovative strategies, including combination therapies and advanced drug delivery systems, that aim to improve their clinical applicability. Overall, this work underscores the relevance of integrating natural bioactives into modern cancer therapy and calls for further translational research to bridge preclinical findings with clinical implementation. Full article

The objective of this research is to investigate whether and how leaders’ sense of calling influences employees’ innovative behavior, and to explore the conditions that may define the boundaries of this effect. Based on the theory of interpersonal sensemaking, this research conducted an empirical analysis using data from 186 pairs of supervisor-subordinate matching questionnaires and developed a moderated mediation model. We hypothesized and found that: first, leaders’ calling directly enhanced employees’ innovative behavior; second, the relationship between the leaders’ calling and employees’ innovative behavior was mediated by the employee’s sense of work meaning; third, the supervisor’s organizational embodiment positively regulated the relationship between the leaders’ calling and the employee’s sense of work meaning. Specifically, when the degree of the supervisor’s organizational embodiment is higher, the relationship between the leaders’ calling and the employee’s work meaning will be stronger. At the same time, the supervisor’s organizational embodiment positively regulates the mediating effect. Specifically, when the degree of the supervisor’s organizational embodiment is higher, the mediating effect of the employee’s work meaning is stronger. Full article

Background: Access to healthy food in emerging-economy cities is challenged by last-mile constraints and poor infrastructure. Aligned with the UN SDGs on Zero Hunger and Sustainable Cities, this study examines how a strategically located nanostores network can help close these gaps while fostering local resilience. Focusing on Colombia’s Sabana Centro region, we designed a nanostore network that maximizes spatial coverage, proximity, and affordability. Methods: A competitive facility-location model combined with a discrete choice model captures consumer heterogeneity in price and location preferences. Results: Results show that locating nanostores in peripheral rather than central areas improves equity: the proposed network meets about 65,400 kg of weekly demand—51% fruit, 36% vegetables, 13% tubers—representing 16% of total regional demand and reaching underserved municipalities. This is notable given that existing nanostores already satisfy roughly 37% of household needs. Conclusions: By linking consumer behavior with sustainable spatial planning, the research offers both theoretical insight and practical tools for equitable distribution. Future work should evaluate supportive policies and supply chain innovations to secure nanostores’ long-term viability and community impact. Full article