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16 pages, 1983 KB  
Article
Evaluation of the Upper Airway in Class II Patients Undergoing Maxillary Setback and Counterclockwise Rotation in Orthognatic Surgery
by Flávio Fidêncio de Lima, Tayná Mendes Inácio De Carvalho, Bianca Pulino, Camila Cerantula, Mônica Grazieli Correa and Raphael Capelli Guerra
Craniomaxillofac. Trauma Reconstr. 2025, 18(3), 39; https://doi.org/10.3390/cmtr18030039 - 4 Sep 2025
Abstract
Introduction: Maxillary setback in orthognathic surgery has been extensively discussed regarding its effects on bone healing and facial soft tissue profile; however, its impact on upper airway volume remains unclear. Objective: We evaluate the influence of maxillary setback combined with counterclockwise (CCW) rotation [...] Read more.
Introduction: Maxillary setback in orthognathic surgery has been extensively discussed regarding its effects on bone healing and facial soft tissue profile; however, its impact on upper airway volume remains unclear. Objective: We evaluate the influence of maxillary setback combined with counterclockwise (CCW) rotation of the occlusal plane on upper airway dimensions. Methods: A retrospective observational case series was conducted with eight patients diagnosed with Class II malocclusion who underwent orthognathic surgery involving maxillary setback and CCW mandibular rotation. All procedures were performed by the same surgeon. Preoperative (T1) and 6-month postoperative (T2) facial CT scans were analyzed using Dolphin Imaging software11.7 to measure airway volume (VOL), surface area (SA), and linear distances D1, D2 and D3. Statistical analysis was performed using the Wilcoxon test with a 5% significance level. Results: Significant skeletal changes were observed, including 10.2 mm of mandibular advancement, 5.2 mm of hyoid advancement, and 4.1° of CCW rotation. Although increases in airway volume and surface area were noted, they did not reach statistical significance (p = 0.327 and p = 0.050, respectively), but suggesting a favorable trend toward airway adaptation. Conclusions: Maxillary setback combined with CCW rotation appears to safely correct Class II skeletal deformities without compromising upper airway space. These preliminary findings highlight the technique’s potential for both functional and aesthetic outcomes, warranting further long-term studies. Full article
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26 pages, 4297 KB  
Article
Numerical Simulation of Transient Two-Phase Flow in the Filling Process of the Vertical Shaft Section of a Water Conveyance Tunnel
by Shuaihui Sun, Jinyang Ma, Bo Zhang, Yangyang Lian, Yulong Xiao and Denglu Zhong
Processes 2025, 13(9), 2832; https://doi.org/10.3390/pr13092832 - 4 Sep 2025
Abstract
Long-distance water conveyance systems require controlled filling after initial operation or maintenance. This process is complex and challenging to manage accurately. It involves transient two-phase flow with rapid velocity and pressure changes, which can risk pipeline damage. Studying the filling process is thus [...] Read more.
Long-distance water conveyance systems require controlled filling after initial operation or maintenance. This process is complex and challenging to manage accurately. It involves transient two-phase flow with rapid velocity and pressure changes, which can risk pipeline damage. Studying the filling process is thus essential to ensure the safe and efficient operation of the system. Combining a specific engineering case, this work investigates gas–liquid two-phase flow in tunnel sections during filling. We employ a coupled Volume of Fluid (VOF) multiphase model and a Realizable k-ε turbulence model for our simulations. Hydraulic parameters (flow patterns, pressure, velocity) are analyzed using the results. Key findings indicate that higher filling flow rates destabilize the process. Gas retention behavior in low-pressure caverns varies, and gas–liquid eruptions occur at shaft water surfaces. Increased flow rates also intensify phase–pattern transitions, elevate peak pressure and velocity values, and amplify pressure pulsations and velocity fluctuations. Furthermore, faster gas transport in low-pressure caverns triggers flow instability, compromising exhaust efficiency. Full article
(This article belongs to the Section Process Control and Monitoring)
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25 pages, 6835 KB  
Article
Hydro-Topographic Contribution to In-Field Crop Yield Variation Using High-Resolution Surface and GPR-Derived Subsurface DEMs
by Jisung Geba Chang, Martha Anderson, Feng Gao, Andrew Russ, Haoteng Zhao, Richard Cirone, Yakov Pachepsky and David M. Johnson
Remote Sens. 2025, 17(17), 3061; https://doi.org/10.3390/rs17173061 - 3 Sep 2025
Abstract
Understanding spatial variability in crop yields across fields is critical for developing precision agricultural strategies that optimize productivity while reducing negative environmental impacts. This variability often arises from a complex interplay of topographic features, soil characteristics, and hydrological conditions. This study investigates the [...] Read more.
Understanding spatial variability in crop yields across fields is critical for developing precision agricultural strategies that optimize productivity while reducing negative environmental impacts. This variability often arises from a complex interplay of topographic features, soil characteristics, and hydrological conditions. This study investigates the influence of hydro-topographic factors on corn and soybean yield variability from 2016 to 2023 at the well-managed experimental sites in Beltsville, Maryland. A high-resolution surface digital elevation model (DEM) and subsurface DEM derived from ground-penetrating radar (GPR) were used to quantify topographic factors (elevation, slope, and aspect) and hydrological factors (surface flow accumulation, depth from the surface to the subsurface-restricting layer, and distance from each crop pixel to the nearest subsurface flow pathway). Topographic variables alone explained yield variation, with a relative root mean square error (RRMSE) of 23.7% (r2 = 0.38). Adding hydrological variables reduced the error to 15.3% (r2 = 0.73), and further combining with remote sensing data improved the explanatory power to an RRMSE of 10.0% (r2 = 0.87). Notably, even without subsurface data, incorporating surface-derived flow accumulation reduced the RRMSE to 18.4% (r2 = 0.62), which is especially important for large-scale cropland applications where subsurface data are often unavailable. Annual spatial yield variation maps were generated using hydro-topographic variables, enabling the identification of long-term persistent yield regions (LTRs), which served as stable references to reduce spatial anomalies and enhance model robustness. In addition, by combining remote sensing data with interannual meteorological variables, prediction models were evaluated with and without hydro-topographic inputs. The inclusion of hydro-topographic variables improved spatial characterization and enhanced prediction accuracy, reducing error by an average of 4.5% across multiple model combinations. These findings highlight the critical role of hydro-topography in explaining spatial yield variation for corn and soybean and support the development of precise, site-specific management strategies to enhance productivity and resource efficiency. Full article
(This article belongs to the Section Remote Sensing in Agriculture and Vegetation)
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14 pages, 855 KB  
Article
Physical Activity and Physical Function One Year After Hospital Discharge for COVID-19
by Eva Arents, Fien Hermans, Lies Glorie, Bihiyga Salhi, Cedric Bosteels, Eric Derom, Wim Janssens, Eva Van Braeckel, Natalie Lorent, Yannick Vande Weygaerde, Thierry Troosters and Heleen Demeyer
J. Clin. Med. 2025, 14(17), 6206; https://doi.org/10.3390/jcm14176206 - 2 Sep 2025
Abstract
Background: Immediately after discharge from hospital, COVID-19 patients have poor physical function and impaired performance in activities of daily living. Persisting symptoms and cognitive impairments have been reported, but the long-term impact on objectively measured physical activity (PA) in patients hospitalized for COVID-19 [...] Read more.
Background: Immediately after discharge from hospital, COVID-19 patients have poor physical function and impaired performance in activities of daily living. Persisting symptoms and cognitive impairments have been reported, but the long-term impact on objectively measured physical activity (PA) in patients hospitalized for COVID-19 is not clear. Methods: A prospective cohort study was conducted to compare objectively measured PA and physical function 12 months post discharge in patients who were hospitalized for COVID-19 with age- and sex-matched healthy controls and to elucidate the impact of ICU admission on these outcomes. PA was objectively assessed using accelerometry in patients, healthy controls, and in a subset of partners of patients. Additionally, lung function, physical function (six-minute walk distance (6 MWD) and isometric quadriceps and handgrip force), symptom experience, and health-related quality of life (HRQoL) were evaluated in patients with and without ICU admission. Results: Included in the study were 101 patients (60 ± 10 years, 69% male), 36 healthy controls (60 ± 9 years, 58% male), and 14 partners (55 ± 8 years, 21% male). Daily step count and movement intensity (MI) during walking in patients were significantly lower compared with healthy controls (6726 ± 328 vs. 8155 ± 555 n.day−1, p = 0.03 and 1.99 ± 0.04 vs. 2.21 ± 0.07 min/s2.day−1, p = 0.005). PA levels of patients and their partners were comparable. Physical function, symptom experience, HRQoL, and PA levels were comparable in patients with and without ICU admission (p > 0.05). Daily step count was weakly positively associated with 6 MWD (r = 0.30). Conclusions: One year post discharge, patients had lower PA levels than healthy controls. ICU admission did not affect physical function, symptoms, HRQoL or activity levels. Full article
(This article belongs to the Section Respiratory Medicine)
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13 pages, 2338 KB  
Article
High-Accuracy Deep Learning-Based Detection and Classification Model in Color-Shift Keying Optical Camera Communication Systems
by Francisca V. Vera Vera, Leonardo Muñoz, Francisco Pérez, Lisandra Bravo Alvarez, Samuel Montejo-Sánchez, Vicente Matus Icaza, Lien Rodríguez-López and Gabriel Saavedra
Sensors 2025, 25(17), 5435; https://doi.org/10.3390/s25175435 - 2 Sep 2025
Abstract
The growing number of connected devices has strained traditional radio frequency wireless networks, driving interest in alternative technologies such as optical wireless communications (OWC). Among OWC solutions, optical camera communication (OCC) stands out as a cost-effective option because it leverages existing devices equipped [...] Read more.
The growing number of connected devices has strained traditional radio frequency wireless networks, driving interest in alternative technologies such as optical wireless communications (OWC). Among OWC solutions, optical camera communication (OCC) stands out as a cost-effective option because it leverages existing devices equipped with cameras, such as smartphones and security systems, without requiring specialized hardware. This paper proposes a novel deep learning-based detection and classification model designed to optimize the receiver’s performance in an OCC system utilizing color-shift keying (CSK) modulation. The receiver was experimentally validated using an 8×8 LED matrix transmitter and a CMOS camera receiver, achieving reliable communication over distances ranging from 30 cm to 3 m under varying ambient conditions. The system employed CSK modulation to encode data into eight distinct color-based symbols transmitted at fixed frequencies. Captured image sequences of these transmissions were processed through a YOLOv8-based detection and classification framework, which achieved 98.4% accuracy in symbol recognition. This high precision minimizes transmission errors, validating the robustness of the approach in real-world environments. The results highlight OCC’s potential for low-cost applications, where high-speed data transfer and long-range are unnecessary, such as Internet of Things connectivity and vehicle-to-vehicle communication. Future work will explore adaptive modulation and coding schemes as well as the integration of more advanced deep learning architectures to improve data rates and system scalability. Full article
(This article belongs to the Special Issue Recent Advances in Optical Wireless Communications)
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16 pages, 685 KB  
Article
Physical Activity Telecoaching in Post-Surgical NSCLC Patients: A Mixed-Methods Pilot Study Exploring Feasibility, Acceptability and Actual Usage
by Eva Arents, Sarah Haesevoets, Fien Hermans, Kirsten Quadflieg, Dries Cops, Maarten Criel, David Ruttens, Veerle Surmont, Bihiyga Salhi, Eric Derom, Thierry Troosters, Dieter Stevens, Chris Burtin and Heleen Demeyer
Cancers 2025, 17(17), 2886; https://doi.org/10.3390/cancers17172886 - 2 Sep 2025
Abstract
Background: Patients with early-stage (I–IIIA) resectable non-small cell lung cancer (NSCLC) often experience reduced physical activity (PA) after surgery. PA telecoaching may support a more active lifestyle, but evidence in this population is limited. Objective: To evaluate acceptability, feasibility, safety, and actual usage [...] Read more.
Background: Patients with early-stage (I–IIIA) resectable non-small cell lung cancer (NSCLC) often experience reduced physical activity (PA) after surgery. PA telecoaching may support a more active lifestyle, but evidence in this population is limited. Objective: To evaluate acceptability, feasibility, safety, and actual usage of an automated and manual PA telecoaching program following surgery for NSCLC. Methods: In this multicenter, single-blind study, patients received either an eight-week automated coaching program (ACP) with a customized smartphone app or a manual coaching program (MCP) with weekly phone calls from a coach. Both groups used an activity tracker, linked to their smartphone, to monitor steps and receive feedback. Primary outcomes included acceptability, feasibility, safety and usage, assessed via questionnaires and interviews. Secondary outcomes included objectively measured PA (accelerometry), functional exercise capacity (six-minute walk distance) and symptoms (dyspnea, fatigue) and quality of life, evaluated via questionnaires. Results: Nineteen patients (12 males; 68 ± 6 years; baseline daily steps 7820 ± 2799) were included. The majority (18/19) found the intervention enjoyable, and a minority (6/19) reported minor smartphone issues. All patients wore the activity tracker consistently. No adverse events occurred. The ACP required significantly less coach contact time compared to the MCP (25 ± 14 vs. 54 ± 15 min, p = 0.0003). No other differences in primary outcomes were observed between groups. Changes in secondary outcomes were limited in both groups. Conclusion: PA telecoaching is feasible, well accepted, and safe in patients with NSCLC post-surgery, with excellent activity tracker adherence. The ACP required less coach involvement. However, increasing PA remains challenging, and no conclusions can be made about the effectiveness of telecoaching. Future research should explore longer interventions in larger populations to assess efficacy and long-term outcomes. Full article
(This article belongs to the Section Cancer Survivorship and Quality of Life)
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17 pages, 1180 KB  
Article
Optimized DSP Framework for 112 Gb/s PM-QPSK Systems with Benchmarking and Complexity–Performance Trade-Off Analysis
by Julien Moussa H. Barakat, Abdullah S. Karar and Bilel Neji
Eng 2025, 6(9), 218; https://doi.org/10.3390/eng6090218 - 2 Sep 2025
Abstract
In order to enhance the performance of 112 Gb/s polarization-multiplexed quadrature phase-shift keying (PM-QPSK) coherent optical receivers, a novel digital signal processing (DSP) framework is presented in this study. The suggested method combines cutting-edge signal processing techniques to address important constraints in long-distance, [...] Read more.
In order to enhance the performance of 112 Gb/s polarization-multiplexed quadrature phase-shift keying (PM-QPSK) coherent optical receivers, a novel digital signal processing (DSP) framework is presented in this study. The suggested method combines cutting-edge signal processing techniques to address important constraints in long-distance, high data rate coherent systems. The framework uses overlap frequency domain equalization (OFDE) for chromatic dispersion (CD) compensation, which offers a cheaper computational cost and higher dispersion control precision than traditional time-domain equalization. An adaptive carrier phase recovery (CPR) technique based on mean-squared differential phase (MSDP) estimation is incorporated to manage phase noise induced by cross-phase modulation (XPM), providing dependable correction under a variety of operating situations. When combined, these techniques significantly increase Q factor performance, and optimum systems can handle transmission distances of up to 2400 km. The suggested DSP approach improves phase stability and dispersion tolerance even in the presence of nonlinear impairments, making it a viable and effective choice for contemporary coherent optical networks. The framework’s competitiveness was evaluated by comparing it against the most recent, cutting-edge DSP methods that were released after 2021. These included CPR systems that were based on kernels, transformers, and machine learning. The findings show that although AI-driven approaches had the highest absolute Q factors, they also required a large amount of computing power. On the other hand, the suggested OFDE in conjunction with adaptive CPR achieved Q factors of up to 11.7 dB over extended distances with a significantly reduced DSP effort, striking a good balance between performance and complexity. Its appropriateness for scalable, long-haul 112 Gb/s PM-QPSK systems is confirmed by a complexity versus performance trade-off analysis, providing a workable and efficient substitute for more resource-intensive alternatives. Full article
(This article belongs to the Section Electrical and Electronic Engineering)
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4 pages, 156 KB  
Editorial
Sustainable Maritime Transportation in Fluctuating Market: Technologies, Innovations, and Challenges
by Guangnian Xiao and Lang Xu
J. Mar. Sci. Eng. 2025, 13(9), 1690; https://doi.org/10.3390/jmse13091690 - 2 Sep 2025
Viewed by 13
Abstract
Maritime transport, carrying over 80% of global trade volume, remains the most energy-efficient mode for long-distance cargo transportation [...] Full article
24 pages, 6760 KB  
Article
Research on the Coordinated Differential Protection Mechanism of a Hybrid DC Multi-Infeed System
by Panrun Jin, Wenqin Song, Huilei Zhao and Yankui Zhang
Eng 2025, 6(9), 217; https://doi.org/10.3390/eng6090217 - 2 Sep 2025
Viewed by 35
Abstract
In order to meet the needs of grid integration of various renewable energy sources and promote long-distance power transmission, a hybrid multi-infeed DC system architecture consisting of a line-commutated converter (LCC) and a modular multilevel converter (MMC) is constructed. Focusing on the issue [...] Read more.
In order to meet the needs of grid integration of various renewable energy sources and promote long-distance power transmission, a hybrid multi-infeed DC system architecture consisting of a line-commutated converter (LCC) and a modular multilevel converter (MMC) is constructed. Focusing on the issue of traditional differential protection refusing to operate under high-resistance grounding faults and failing under symmetrical faults, a dual-criteria protection mechanism is proposed in this paper. By integrating current differential and voltage criterion, the accurate identification of various types of AC line faults can be realized. A hybrid DC system simulation model was built on MATLAB, the sampled data was decoupled, and the differential quantity was calculated to test the dual-criteria protection mechanism. The simulation results show that the proposed protection mechanism can effectively identify various faults within the hybrid DC multi-feed system area and faults outside the area and has robustness to complex working conditions such as high-resistance grounding and three-phase short circuits, which improves the sensitivity, selectivity, and adaptability of the protection. This method is designed for AC line protection under the disturbance of multi-infeed DC systems. It is not directly applicable to pure DC microgrids. The concept can be extended to AC/DC hybrid microgrids by adding DC-side protection criteria and re-calibrating thresholds. Full article
(This article belongs to the Section Electrical and Electronic Engineering)
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13 pages, 3256 KB  
Article
Characteristics of GaN-Based Micro-Light-Emitting Diodes for Mbps Medium-Long Distance Underwater Visible Light Communication
by Zhou Wang, Yijing Lin, Yuhang Dai, Jiakui Fan, Weihong Sun, Junyuan Chen, Siqi Yang, Shiting Dou, Haoxiang Zhu, Yan Gu, Jin Wang, Hao Zhang, Qiang Chen and Xiaoyan Liu
Nanomaterials 2025, 15(17), 1347; https://doi.org/10.3390/nano15171347 - 2 Sep 2025
Viewed by 138
Abstract
To promote the development of long-distance high-speed underwater optical wireless communication (UWOC) based on visible light, this study proposes a high-bandwidth UWOC system based on micro-light-emitting-diodes (micro-LEDs) adopting the Non-Return-to-Zero On-Off Keying (NRZ-OOK) modulation. The numerical simulations reveal that optimizing the structural parameters [...] Read more.
To promote the development of long-distance high-speed underwater optical wireless communication (UWOC) based on visible light, this study proposes a high-bandwidth UWOC system based on micro-light-emitting-diodes (micro-LEDs) adopting the Non-Return-to-Zero On-Off Keying (NRZ-OOK) modulation. The numerical simulations reveal that optimizing the structural parameters of gallium nitride (GaN)-based micro-LED through dimensional scaling and quantum well layer reduction may significantly enhance optoelectronic performance, including modulation bandwidth and luminous efficiency. Moreover, experimental validation demonstrated maximum real-time data rates of 420 Mbps, 290 Mbps, and 250 Mbps at underwater distances of 2.3 m, 6.9 m, and 11.5 m, respectively. Furthermore, the underwater audio communication was successfully implemented at an 11.5 m UWOC distance at an ultra-low level of incoming optical power (12.5 µW) at the photodetector (PD) site. The channel characterization yielded a micro-LED-specific attenuation coefficient of 0.56 dB/m, while parametric analysis revealed wavelength-dependent degradation patterns, exhibiting positive correlations between both attenuation coefficient and bit error rate (BER) with operational wavelength. This study provides valuable insights for optimizing underwater optical systems to enhance real-time environmental monitoring capabilities and strengthen security protocols for subaquatic military communications in the future. Full article
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22 pages, 2039 KB  
Article
ML and Statistics-Driven Route Planning: Effective Solutions Without Maps
by Péter Veres
Logistics 2025, 9(3), 124; https://doi.org/10.3390/logistics9030124 - 1 Sep 2025
Viewed by 131
Abstract
Background: Accurate route planning is a core challenge in logistics, particularly for small- and medium-sized enterprises that lack access to costly geospatial tools. This study explores whether usable distance matrices and routing outputs can be generated solely from geographic coordinates without relying [...] Read more.
Background: Accurate route planning is a core challenge in logistics, particularly for small- and medium-sized enterprises that lack access to costly geospatial tools. This study explores whether usable distance matrices and routing outputs can be generated solely from geographic coordinates without relying on full map-based infrastructure. Methods: A dataset of over 5000 Hungarian postal locations was used to evaluate five models: Haversine-based scaling with circuity, linear regression, second- and third-degree polynomial regressions, and a trained artificial neural network. Models were tested on the full dataset, and three example routes representing short, medium, and long distances. Both statistical accuracy and route-level performance were assessed, including a practical optimization task. Results: Statistical models maintained internal consistency, but systematically overestimated longer distances. The ANN model provided significantly better accuracy across all scales and produced routes more consistent with map-based paths. A new evaluation method was introduced to directly compare routing outputs. Conclusions: Practical route planning can be achieved without GIS services. ML-based estimators offer a cost-effective alternative, with potential for further improvement using larger datasets, additional input features, and the integration of travel time prediction. This approach bridges the gap between simplified approximations and commercial routing systems. Full article
(This article belongs to the Section Artificial Intelligence, Logistics Analytics, and Automation)
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15 pages, 10812 KB  
Review
The Yellow Sea Green Tides: Spatiotemporal Dynamics of Long-Distance Transport and Influencing Factors
by Fanzhu Qu, Bowen Sun, Ling Meng and Tao Zou
Diversity 2025, 17(9), 614; https://doi.org/10.3390/d17090614 - 1 Sep 2025
Viewed by 46
Abstract
Since 2007, the Yellow Sea has experienced the world’s largest green tides, with Ulva prolifera O.F. Müller as the dominant species. Those blooms severely impacted the local tourism and aquaculture, resulting in significant economic losses, as well as negative social and ecological consequences. [...] Read more.
Since 2007, the Yellow Sea has experienced the world’s largest green tides, with Ulva prolifera O.F. Müller as the dominant species. Those blooms severely impacted the local tourism and aquaculture, resulting in significant economic losses, as well as negative social and ecological consequences. Unlike other global green tides, those in the Yellow Sea are characterized by long-distance drifting and an astonishing scale. These destructive events display significant temporal and spatial variability, which is largely driven by dynamic environmental conditions and human activities. In this review, we summarize recent advancements in understanding the spatiotemporal patterns of long-distance transport, the interannual variability in bloom size, and the underlying mechanisms driving these fluctuations. Additionally, we highlight important knowledge gaps that need further investigation to support the development of effective management strategies for mitigating the impacts of green tides in the Yellow Sea. Full article
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11 pages, 3793 KB  
Communication
Electronic Properties of Parallel-Aligned Arrays of Carbon Nanotubes
by Bartosz Brzostowski and Jacek Wojtkiewicz
Materials 2025, 18(17), 4095; https://doi.org/10.3390/ma18174095 - 1 Sep 2025
Viewed by 127
Abstract
We present results of electronic properties’ DFT calculations, i.e., band structure, density of states and energy gap for arrays of parallel-ordered infinitely long small-diameter carbon nanotubes (CNTs). It turns out that if the distance between CNTs is sufficiently large (of the order 7.5 [...] Read more.
We present results of electronic properties’ DFT calculations, i.e., band structure, density of states and energy gap for arrays of parallel-ordered infinitely long small-diameter carbon nanotubes (CNTs). It turns out that if the distance between CNTs is sufficiently large (of the order 7.5 Å or greater), the electronic properties of arrays are very close to isolated CNTs. However, when CNTs in arrays are forced to be at a distance of the order of 5 Å, they undergo radical structural rearrangements, leading to completely different structures: graphite-like or three-dimensional lattice intermediates between graphite and diamond. Electronic properties are also rebuilt in a drastic manner. Full article
(This article belongs to the Special Issue Electronic, Optical, and Structural Properties of Carbon Nanotubes)
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12 pages, 310 KB  
Article
A Centrally Peripheral Publisher: The Fostering of the Hui Literary Field in Post-Mao China
by Mario De Grandis
Humanities 2025, 14(9), 178; https://doi.org/10.3390/h14090178 - 1 Sep 2025
Viewed by 145
Abstract
In recent decades, Chinese literary studies has shifted away from center–periphery models, favoring frameworks that emphasize multiplicity and decentralization. While this turn has opened space for new perspectives, it risks overlooking persistent hierarchies that continue to shape literary careers, where certain publishers remain [...] Read more.
In recent decades, Chinese literary studies has shifted away from center–periphery models, favoring frameworks that emphasize multiplicity and decentralization. While this turn has opened space for new perspectives, it risks overlooking persistent hierarchies that continue to shape literary careers, where certain publishers remain more central to an author’s advancement than others. This essay reconsiders the center–periphery framework through an analysis of Huizu wenxue, a literary journal published in Changji, Xinjiang Uygur Autonomous Region. Despite its geographic distance from China’s dominant literary hubs, Huizu wenxue has long served as a key platform for Hui literature. Drawing on interviews, as well as textual and paratextual analysis, I demonstrate how the journal functions both as a launchpad for emerging Hui authors and as an institutional anchor for a nationwide Hui literary community. Through dedicated columns that showcase new Hui talent and events that foster professional networks, Huizu wenxue has, since its inception, continually played a central role in shaping Hui literary production and supporting authors’ careers. Because it operates from the margins of the People’s Republic of China’s yet wields significant influence within Hui literary circles, I argue that Huizu wenxue is best understood as a “peripheral center.” Full article
(This article belongs to the Section Literature in the Humanities)
14 pages, 3484 KB  
Article
Multiparametric Quantitative Ultrasound as a Potential Imaging Biomarker for Noninvasive Detection of Nonalcoholic Steatohepatitis: A Clinical Feasibility Study
by Trina Chattopadhyay, Hsien-Jung Chan, Duy Chi Le, Chiao-Yin Wang, Dar-In Tai, Zhuhuang Zhou and Po-Hsiang Tsui
Diagnostics 2025, 15(17), 2214; https://doi.org/10.3390/diagnostics15172214 - 1 Sep 2025
Viewed by 171
Abstract
Objectives: The FibroScan–aspartate transaminase (AST) score (FAST score) is a hybrid biomarker combining ultrasound and blood test data for identifying nonalcoholic steatohepatitis (NASH). This study aimed to assess the feasibility of using quantitative ultrasound (QUS) biomarkers related to hepatic steatosis for NASH [...] Read more.
Objectives: The FibroScan–aspartate transaminase (AST) score (FAST score) is a hybrid biomarker combining ultrasound and blood test data for identifying nonalcoholic steatohepatitis (NASH). This study aimed to assess the feasibility of using quantitative ultrasound (QUS) biomarkers related to hepatic steatosis for NASH detection and to compare their diagnostic performance with the FAST score. Methods: A total of 137 participants, comprising 71 individuals with NASH and 66 with non-NASH (including 49 normal controls), underwent FibroScan and ultrasound exams. QUS imaging features (Nakagami parameter m, homodyned-K parameter μ, entropy H, and attenuation coefficient α) were extracted from backscattered radiofrequency data. A weighted QUS parameter based on m, μ, H, and α was derived via linear discriminant analysis. NASH was diagnosed based on liver biopsy findings using the nonalcoholic fatty liver disease activity score (NAS). Diagnostic performance was evaluated using the area under the receiver operating characteristic curve (AUROC) and compared with the FAST score using the DeLong test. Separation metrics, including the complement of overlap coefficient, Bhattacharyya distance, Kullback–Leibler divergence, and silhouette score, were used to assess inter-group separability. Results: All QUS parameters were significantly elevated in NASH patients (p < 0.05). AUROC values for individual QUS features ranged from 0.82 to 0.91, with the weighted QUS parameter achieving 0.91. The FAST score had the highest AUROC (0.96), though differences with the weighted QUS and homodyned-K parameters were not statistically significant (p > 0.05). Separation metrics ranked the FAST score highest, closely followed by the weighted QUS parameter. Conclusions: QUS biomarkers can be repurposed for NASH detection, with the weighted QUS parameter offering diagnostic accuracy comparable to the FAST score and serving as a promising, blood-free alternative. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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